Personal information

Verified email domains

Portugal

Biography

Bruno Sarmento graduated in Pharmaceutical Sciences and is PhD in Pharmaceutical Nanotechnology at Univ Porto, in collaboration with Queen’s Univ, Univ Copenhagen and Univ Santiago de Compostela. He was post-doc fellow at Univ Porto in collaboration with Univ Copenhagen. In 2012 he became Associated Researcher at INEB, now part of i3S, Assistant Researched in 2016 and Principal Investigator in 2019, where he leads the Nanomedicines & Translational Drug Delivery group. He is currently invited Associate Professor at IUCS. He was Visiting Professor at UniOeste (BR) between 2015-2017 and at Shanghai Jiao Tong University (CH) between 2022-2024.

His research interests cover cutting-edge drug delivery systems, with a keen focus on nanomedicine. He has made significant and multidisciplinary contributions on engineering nanomedicines, multistage macroplatforms and 3D multicompartmental cell-based models, closely resembling the basic characteristics of healthy and injured tissues, as reliable pre-clinical platforms for drug and nanomedicines efficacy screening.

He has nurtured scientists and innovators by education and training, supervising 20 Post-Docs, 55 PhD and 40 MSc students and 20 researcher assistants. His group holds vary scientific backgrounds, diversity by gender (20% male/80% female), including researchers from more than 15 countries.

He hosted more than 25 mobility/foreigner PhD students, fostering a vibrant exchange of ideas and expertise and resulting in multiple publications in collaboration with international co-authors.

His research garnered international recognition, evident in his publication record of over 500 papers (>23000 citations, H-index 76), and more than 60 invited talks in international meetings in 20 countries. He attracted competitive funding from national (FCT, CCDR-N, CESPU) and international (EC, NIH, CAPES, FAPESP, Crohn’s & Colitis Foundation) grants, and partnership with pharmaceutical industries.

He serves the i3S Board of Directors since 2020, Director-at-Large and Secretary of the Controlled Release Society (CRS) and member of CRS College of Fellows. He is editor of Eur J Pharm Sci and Drug Deliv Transl Res, and Advisory Board of others as J Control Rel and Exp Opin Drug Deliv. He is a regular reviewer for high rank journals (Nat Nanotechnol, Sci Adv, Nat Com, Adv Mat, J Control Rel) and funding agencies (FNRS (BE), FWO(BE), CNCS (RO), FCT (PT), NSC (PL), ANR (FR), CNPq (BR), ERC, MC Actions, PathFinder, FetOpen (EC)).

Activities

Employment (2)

INEB/i3S: Porto, PT

Principal Investigator
Employment
Source: Self-asserted source
Bruno Sarmento

Cooperativa de Ensino Superior Politécnico e Universitário: Gandra, PT

Invited Associate Professor
Employment
Source: Self-asserted source
Bruno Sarmento

Education and qualifications (2)

Universidade do Porto: Porto, PT

2004-01-01 to 2007-10-18 | PhD
Education
Source: Self-asserted source
Bruno Sarmento

Universidade do Porto: Porto, PT

2002-05-02 | Pharm D
Education
Source: Self-asserted source
Bruno Sarmento

Professional activities (2)

European Journal of Pharmaceutical Sciences: Amesterdan, NL

2018-10-01 to present
Membership
Source: Self-asserted source
Bruno Sarmento

Controlled Release Society: New Jersey, US

2018-01-01 to present | Board Member
Membership
Source: Self-asserted source
Bruno Sarmento

Funding (60)

FibHep: um modelo 3D in vitro de fibrose humana em hepatite

2025-02-01 to 2027-01-31 | Grant
Gilead Sciences (Boulogne, FR)
GRANT_NUMBER:

FibHep: um modelo 3D in vitro de fibrose humana em hepatite

Source: check_circle
CIÊNCIAVITAE

A novel biofunctional nanoparticle-based system for immuno-chemotherapy delivery in rectal cancer

2024-01 to 2024-12 | Grant
Cooperativa de Ensino Superior Politécnico e Universitário CRL (Gandra, PT)
GRANT_NUMBER:

ChImuRet_GI2-CESPU-2023

Source: check_circle
CIÊNCIAVITAE

Novas formulações farmacêuticas para fototerapia do cancro retal

2023-03-12 to 2024-09-11 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

2022.04494.PTDC

Source: check_circle
CIÊNCIAVITAE

Oxidative-responsive nanomedicines for managing inflammatory bowel disease

2023-01 to 2024-12 | Grant
Crohn's and Colitis Foundation (NY, NY, US)
Source: Self-asserted source
Bruno Sarmento

Oxidative-responsive nanomedicines for managing inflammatory bowel disease

2023-01 to 2024-12 | Grant
Crohn's & Colitis Foundation (New York, US)
GRANT_NUMBER:

937924/Litwin IBD Pioneers Program

Source: check_circle
CIÊNCIAVITAE

Bridging iRon metabolism and immunE cells at the irrAdiateD tumOUr microenvironmenT to identify novel therapeutic targets in rectal cancer

2022-01-17 to 2024-01-16 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

EXPL/BIA-CEL/1225/2021

Source: check_circle
CIÊNCIAVITAE

Dissect the tumor microenvironment to battle cancer radioresistance and immune escape

2022-01-01 to 2024-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-ONC/4165/2021

Source: check_circle
CIÊNCIAVITAE

RESOLVE: Rational Design of Multivalent Glycocode-Inspired Nanovaccines for Gastric Cancer Immunotherapy

2022-01-01 to 2024-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-OUT/2512/2021

Source: check_circle
CIÊNCIAVITAE

Institute for Research and Innovation in Health - LA

2021-01-01 to 2025-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

LA/P/0070/2020

Source: check_circle
CIÊNCIAVITAE

Glioblastoma Next Top Multi 3D Model for Anti-angiogenic Nanomedicines Efficacy Testing

2021 to present | Grant
N/A (N/A, PT)
GRANT_NUMBER:

2021_GBM_Multi3D_PI2RL_IINFACTS_2021

Source: check_circle
CIÊNCIAVITAE

Molecular Bioengineering in health ERA chair

2021 to 2026 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Proposal 951723 MOBILIsE

Source: check_circle
CIÊNCIAVITAE

Firefighting occupational exposure and early effects on the health of operational forces

2021 to 2024 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PCIF/SSO/0090/2019

Source: check_circle
CIÊNCIAVITAE

RESTORE

2019-02 to present | Contract
European Commission (Bruxels, BE)
GRANT_NUMBER:

H2020-NMBP-TR-IND-2018-814558-2

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Instituto de Investigação e Inovação em Saúde

2019-01-01 to 2019-12-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

UID/BIM/04293/2019

Source: check_circle
CIÊNCIAVITAE

Biological assessment of debris from oral implants

2019 to 2021 | Grant
Cooperativa de Ensino Superior Politécnico e Universitário (Gandra, PT)
GRANT_NUMBER:

IMPLDEBRIS-PL-3RL-IINFACTS-2019

Source: check_circle
CIÊNCIAVITAE

PANCREASMIMETIC - Establishment of a multifunctional stimuli-responsive PANCREAS MIMETIC

2018-10-01 to 2023-04-30 | Grant
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/MED-OUT/30466/2017

Source: check_circle
CIÊNCIAVITAE

2BBone - Sintering-free bifunctional CaP-based biomaterials for bone cancer treatment and regeneration

2018-07 to present | Contract
Ministério da Ciência, Tecnologia e Ensino Superior (Porto, PT)
GRANT_NUMBER:

PTDC/CTM-CER/29940/2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Castanea sativa shells as a new source of active ingredients for Functional Food and Cosmetic applications: a sustainable approach

2018-07 to present | Contract
Ministério da Ciência, Tecnologia e Ensino Superior (Porto, Porto, PT)
GRANT_NUMBER:

PTDC/ASP-AGR/29277/2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

MicroMOB - The microbiome mobility pathway in chronic kidney disease and its role in infection and systemic inflammation

2018-07 to present | Contract
Ministério da Ciência, Tecnologia e Ensino Superior (Porto, Porto, PT)
GRANT_NUMBER:

PTDC/MEC-MCI/29777/2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

New platforms for dermatological phototherapy

2018-07 to present | Contract
Ministério da Ciência, Tecnologia e Ensino Superior (Porto, Porto, PT)
GRANT_NUMBER:

PTDC/BTM-MAT/31143/2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Synthesis of psedoboehmite nanoparticles

2018-07 to present | Contract
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (São Paulo, BR)
GRANT_NUMBER:

22396-4/2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

CA 17140 - Cancer nanomedicine - from the bench to the bedside

2018 to present | Grant
N/A (N/A, PT)
GRANT_NUMBER:

COST Action

Source: check_circle
CIÊNCIAVITAE

Development of antibody-functionalized PLGA-PEG nanoparticles to target the carcinoembryonic antigen receptor on colorectal cancer

2018 to present | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Project PI4AC 2018

Source: check_circle
CIÊNCIAVITAE

European Network of Bioadhesion Expertise: Fundamental Knowledge to Inspire Advanced Bonding Technologies

2018 to present | Grant
N/A (N/A, PT)
GRANT_NUMBER:

COST Action, ENBA CA15216

Source: check_circle
CIÊNCIAVITAE

p28Nano - Cell penetrating p28 peptide-mediated delivery of nanomedicines for cancer treatmen

2018 to 2021 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PTDC/CTM-CER/30034/2017

Source: check_circle
CIÊNCIAVITAE

Tailored microenCAPsulation technology for Extreme Oxygen-Sensitive BACteria with beneficial effects in the gut microbiota: Production, stability and functionality enhancements in various carriers

2018 to 2021 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PTDC/BAA-AGR/31400/2017

Source: check_circle
CIÊNCIAVITAE

Establishment of new muco-interactive nanomicelles as oral delivery systems of camptothecin for colorectal cancer

2017-04 to 2018-03 | Contract
CESPU (Gandra, PT)
GRANT_NUMBER:

MicelCampt-CESPU-2017

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Nano-ThERM: Nanopartículas em Enema Termossensível para o Desenvolvimento de Microbicidas Retais Anti-VIH

2017-01 to 2018-12 | Contract
Gilead Sciences (Lisboa, CA, PT)
GRANT_NUMBER:

PGG/002/2016

Source: Self-asserted source
Bruno Sarmento

Nano-ThERM: Nanopartículas em Enema Termossensível para o Desenvolvimento de Microbicidas Retais Anti-VIH

2017-01 to 2018-12 | Grant
Gilead Sciences Inc (Westminster, US)
GRANT_NUMBER:

PGG/002/2016

Source: check_circle
CIÊNCIAVITAE

Exploring microfluidics-based devices for next-generation probiotics encapsulation

2017 to 2017 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Project PI4AC 2017

Source: check_circle
CIÊNCIAVITAE

NETDIAMOND – New targets in diastolic heart failure: from comorbidities to personalized medicine

2016-12 to 2019-11 | Contract
Ministério da Ciência, Tecnologia e Ensino Superior (Porto, PT)
GRANT_NUMBER:

C441894815-00037491

Source: Self-asserted source
Bruno Sarmento

NETDIAMOND – New targets in diastolic heart failure: from comorbidities to personalized medicine

2016-12 to 2019-11 | Grant
Ministério da Ciência Tecnologia e Ensino Superior (Lisboa, PT)
GRANT_NUMBER:

C441894815-00037491

Source: check_circle
CIÊNCIAVITAE

Instituto de Bioengenieria en Red para el Envejecimento Saludable

2016-09 to 2020-03 | Contract
European Commission (Brussels, BE)
Source: Self-asserted source
Bruno Sarmento

FutForm - Future formulations: Developing future pharmaceuticals through advanced analysis and intersectoral exchange

2016-04 to 2019-03 | Grant
European Commission (Brussels, BE)
Source: Self-asserted source
Bruno Sarmento

Development of biocomposites fibrous scaffolds as topical 5-fluorouracil carriers for inhibiting hypertrophic scar

2016-04 to 2017-03 | Grant
CESPU (Gandra, PT)
GRANT_NUMBER:

ElectrospunnScar-CESPU-2016

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Development of oral strips containing nanoencapsulated bioactive compounds

2016-01 to 2019-12 | Grant
Fundação para a Ciência e Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER:

PTDC/BBB-NAN/3249/2014

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Bioengineered therapies for infectious diseases and tissue regeneration

2016-01 to 2018-12 | Contract
CCDR (Porto, PT)
GRANT_NUMBER:

NORTE-01-0145-FEDER-000012

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

Filmes vaginais contendo nanopartículas carregadas com fármacos como alternativa à profilaxia de pré-exposição oral com tenofovir/emtricitabina

2016-01 to 2017-12 | Grant
Gilead Sciences (Lisboa, PT)
GRANT_NUMBER:

PGG/046/2015

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 3)‎

Bioengineered FcRn-targeting nanoparticles for intestinal delivery of biopharmaceuticals

2016 to present | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Project PI3AC 2016

Source: check_circle
CIÊNCIAVITAE

Instituto de Bioengenieria en Red para el Envejecimento Saludable

2016 to 2019 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

INTERREG (POCTEP), FEDER

Source: check_circle
CIÊNCIAVITAE

FutForm - Future formulations: Developing future pharmaceuticals through advanced analysis and intersectoral exchange, member

2015 to 2019 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

H2020-MSCA-RISE-2015

Source: check_circle
CIÊNCIAVITAE

Development of combination antiretroviral-loaded nanoparticles-in-vaginal film systems for preventing HIV transmission

2014-03 to 2016-02 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER: 123646
GRANT_NUMBER:

VIH/SAU/0021/2011

Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 2)‎

Biomateriais termosensíveis à base de polissacarídeos da flora brasileira para nanoencapsulação de fármacos anticancerígenos

2014 to 2015 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Project R and D in Pharmaceutical Sciences

Source: check_circle
CIÊNCIAVITAE

SO2S— The Singlet Oxygen Strategy: sustainable oxidation procedures for applications in material science, synthesis, wastewater treatment, diagnostics and therapeutics

2013-01 to present | Grant
European Commission (Brussels, BE)
GRANT_NUMBER:

FP7-PEOPLE-2012-ITN, PITN-GA-2012-316975

Source: Self-asserted source
Bruno Sarmento
grade
Preferred source (of 2)‎

NANODAIRY - NANOparticles as Delivery systems of bioactive polyphenolic compounds to DAIRY matrices: evaluation of stability, bioavailability and toxicity.

2012-03 to 2015-02 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER: 117808
GRANT_NUMBER:

PTDC/AGR-ALI/117808/2010

Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 2)‎

InVitroBrain - Development of a humanized dynamic in vitro blood-brain barrier model and a vesicle-based barrier for brain penetration of drugs incorporated in lipid nanoparticles - Closing the gap between in vivo and in vitro properties

2011-07-01 to 2014-06-30 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER: 112277
Source: Self-asserted source
Bruno Sarmento via DimensionsWizard
grade
Preferred source (of 2)‎

Developing of new targets for cancer treatment based on siRNA contained into functionalized nanoparticles

2011 to 2013 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

02-GCQF-CICS-11N- CESPU

Source: check_circle
CIÊNCIAVITAE

Novel Targeted Chitosan-Based Therapeutic Polymeric Nanomedicines for Lung Cancer Applications

2011 to 2013 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

Indo-Portuguese Research Cooperation in Science and Technology 2010-2011

Source: check_circle
CIÊNCIAVITAE

Produção e aplicação de bioprotector com quitosano fúngico na nutrição e conservação de alimentos

2011 to 2012 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

FCT-CAPES (Portugal-Brasil) 2011-2012

Source: check_circle
CIÊNCIAVITAE

Desenvolvimento e validação de um modelo farmacocinético/farmacodinâmico para a individualização das doses de carboplatina e gemcitabina a administrar em doentes idosos com carcinoma de pulmão de não pequenas células avançado

2010-05-01 to 2013-10-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

PTDC/SAU-FCT/104448/2008

Source: check_circle
CIÊNCIAVITAE

NanoFreeze - Freeze-drying approaches for overcoming instability of therapeutic proteins encapsulated into nanoparticles

2010-04-01 to 2013-04-30 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER: 104492
Source: Self-asserted source
Bruno Sarmento via DimensionsWizard
grade
Preferred source (of 2)‎

EncapsDevice: Development of polymeric nanostructures for nasal and pulmonary delivery of peptides and proteins

2010-01 to 2013-06 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER: 100291
GRANT_NUMBER:

PTDC/SAU-FCF/100291/2008

Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 2)‎

Nanoencapsulation of antituberculous drugs in mucoadhesive chitosan nanoparticles for the inhalatory release and the pulmonary targeting of bacterial reservoirs in the treatment of tuberculosis

2010 to 2011 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

FCT-MINCYT (Portugal-Argentina) 2010-2011, PO/09/35

Source: check_circle
CIÊNCIAVITAE

“Development and validation of a pharmacokinetic/pharmacodynamic model to individualize carboplatin and gemcitabine doses elderly patients with advanced non-small cell lung cancer

2009 to 2012 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

PTDC/SAU-FCF/104448/2008

Source: check_circle
CIÊNCIAVITAE

"Estratégias para redução da fagocitose de nanopartículas contendo proteínas terapêuticas pelo de sistema mononuclear fagocitário

2009 to 2010 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

02-GCQF-CICS-09 - CESPU

Source: check_circle
CIÊNCIAVITAE

Polímeros terapêuticos conjugados como transportadores específicos de material genético no tratamento do cancro de pulmão de não-pequenas células

2009 to 2010 | Grant
N/A (N/A, PT)
GRANT_NUMBER:

05-GCQF-CICS- 09

Source: check_circle
CIÊNCIAVITAE

STUDY OF INSULIN INTESTINAL ABSORPTION MECHANISMS USING A NEW IN VITRO HUMAN INTESTINE VERSUS IN VIVO DIABETIC ANIMAL MODELS

2007-11-01 to 2012-10-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BPD/35996/2007

Source: check_circle
CIÊNCIAVITAE

IN VIVO/IN VITRO CORRELATION OF INTESTINAL ABSORPTION OF PROTEINS USING ANIMAL MODELS AND CACO-2 BASED CO-CULTURE CELL LINES

2007-07 to 2011-06 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER: 70651
GRANT_NUMBER:

PTDC/SAU-FCF/70651/2006

Source: check_circle
CIÊNCIAVITAE
grade
Preferred source (of 2)‎

Improvement of insulin oral availability through encapsulation in polyelectrolyte complex nanoparticles

2005-09-01 to 2008-08-31 | Grant
Fundação para a Ciência e a Tecnologia, I.P. (Lisbon, PT)
GRANT_NUMBER: 59940
Source: Self-asserted source
Bruno Sarmento via DimensionsWizard
grade
Preferred source (of 2)‎

IMPROVEMENT OF PEPTIDIC DRUGS ORAL AVAILABILITY THROUGH THEIR ENCAPSULATION IN POLYELECTROLYTES COMPLEXES

2004-01-01 to 2007-10-31 | Contract
Fundação para a Ciência e a Tecnologia (Lisboa, PT)
GRANT_NUMBER:

SFRH/BD/13082/2003

Source: check_circle
CIÊNCIAVITAE

Peer review (21 reviews for 10 publications/grants)

Review activity for ACS applied bio materials. (1)
Review activity for ACS applied materials & interfaces. (5)
Review activity for ACS biomaterials science & engineering. (1)
Review activity for ACS nano. (3)
Review activity for Advanced healthcare materials (2)
Review activity for Advanced materials. (2)
Review activity for Molecular pharmaceutics. (2)
Review activity for Nano letters. (2)
Review activity for Nature communications (2)
Review activity for Nature nanotechnology (1)