Cardiomyopathies: classification, clinical characterization, and functional phenotypes.
Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the Myosin motor.
The Conformational State of Actin Filaments Regulates Branching by Actin-related Protein 2/3 (Arp2/3) Complex.
Effects of basic calponin on the flexural mechanics and stability of F-actin.
Structural studies on maturing actin filaments.
Germinal center-specific protein human germinal center associated lymphoma directly interacts with both myosin and actin and increases the binding of myosin to actin.
A Hearing Loss-Associated myo1c Mutation (R156W) Decreases the Myosin Duty Ratio and Force Sensitivity.
Cardiomyopathy-linked myosin regulatory light chain mutations disrupt myosin strain-dependent biochemistry.
The molecular basis of frictional loads in the in vitro motility assay with applications to the study of the loaded mechanochemistry of molecular motors.
The direct molecular effects of fatigue and myosin regulatory light chain phosphorylation on the actomyosin contractile apparatus.
Actin in action and inaction: the differential effects of hypertrophic and dilated cardiomyopathy actin mutations on thin filament regulation.
Removal of the cardiac myosin regulatory light chain increases isometric force production.
The molecular effects of skeletal muscle myosin regulatory light chain phosphorylation.
Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics.
Modulation of actin mechanics by caldesmon and tropomyosin.
Myosin regulatory light chain E22K mutation results in decreased cardiac intracellular calcium and force transients.
Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.
Does the myosin V neck region act as a lever?
Myosin V exhibits a high duty cycle and large unitary displacement.
Changes in myofibrillar structure and function produced by N-terminal deletion of the regulatory light chain in Drosophila.
The effect of removing the N-terminal extension of the Drosophila myosin regulatory light chain upon flight ability and the contractile dynamics of indirect flight muscle.
Role of the elastic protein projectin in stretch activation and work output of Drosophila flight muscles.
The Drosophila projectin mutant, bentD, has reduced stretch activation and altered indirect flight muscle kinetics.
A genetic deficiency that spans the flightin gene of Drosophila melanogaster affects the ultrastructure and function of the flight muscles.
Work production and work absorption in muscle strips from vertebrate cardiac and insect flight muscle fibers.
Phosphorylation-dependent power output of transgenic flies: an integrated study.