Ian Robey

tumor, pH, invasion, sodium bicarbonate


My research program is focused on understanding how extracellular pH influences tumor behavior. I am interested in the mechanisms driving acid-mediated invasion and metastases. Another major goal of my studies is to determine if systemic alkaline buffering is effective as an interventional or adjunctive therapy in the prevention or treatment of cancer. My other research focus is on the role of glycolysis, acidity, and hypoxia in tumor progression. The long-term objective of my project is to advance the preclinical findings on the effects of tumor alkalinization to promote the application of eventual clinical trials. I will establish an independent research program with a collaborative focus on bridging integrative medicine and diagnosis/therapy driven non-invasive imaging methodologies.