I am a Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco and a researcher at the San Francisco Veterans Affairs Medical Center. I earned my PhD in Physics from the Ruprecht Karls University of Heidelberg/Germany in 1983. From 1984 to 1992, I developed MRI systems first with Bruker GmbH in Karlsruhe/Germany and later with Varian Associates in Palo Alto, California. In 1993, I joined UCSF.
I study brain diseases such as Alzheimer's and Parkinson's using imaging. My main interest is to improve diagnosis and measure progression of brain diseases. I accomplish this by developing novel computational methods for analyzing brain images using MRI physics as well as modern concepts of probability theory and statistical learning.