Eric Prossnitz completed his Ph.D. degree at the University of California, Berkeley, CA, USA, and subsequently carried out postdoctoral studies at the Scripps Research Institute, La Jolla, CA, USA. He joined the faculty of the Scripps Research Institute in 1994 and was recruited at the University of New Mexico in 1997, where he is the Victor and Ruby Hansen Surface Chair of Cancer Chemical Biology. Prossnitz is currently the co-Director of the Translational Cancer Biology and Signaling Program at the UNM Cancer Center, Director of the Team Science Component of the UNM Clinical and Translational Science Center, and has been a co-Leader of the UNM Center for Molecular Discovery. His major areas of research are in the function of G protein-coupled receptors, including chemoattractant receptors and the estrogen receptor GPR30/GPER with over 200 publications. His studies on the mechanisms of estrogen action and GPER function have elucidated novel biology in the reproductive, immune, cardiovascular, nervous, and endocrine systems as well as in cancer. His efforts also led to the identification of the first selective agonist and antagonist of GPER, both of which are now widely used to assess mechanisms of estrogen action in health and disease.