Daniel Hoyer

ORCID iD
https://orcid.org/0000-0002-1405-7089
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Australia

Sources:
Daniel Hoyer (2016-01-24)

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Daniel Hoyer (2015-04-01)

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Scopus Author ID: 7102283515

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Scopus to ORCID (2015-04-01)

Biography

30 years of drug discovery / development experience in pharmaceutical industry and academia Sandoz: 1979 - 1981; 1983 - 1997; Novartis: 1997 - Nov 2012; Scripps: 2004 - present The University of Melbourne: December 2012 - present Management of pharmacology research groups, drug discovery programmes, compound profiling teams, translational biology. Responsibility for extensive cross disciplinary internal and external interactions / collaborations. Leadership of large learned societies and numerous editorial and academic activities. Establishment of Project Mercury (BioCurate PTY Ltd) between Monash University and University of Melbourne: an $ 80 Mio translational Biomed enterprise with $ 10 Mio support from Vic Govt. Therapeutic / other areas of interest: Sleep disorders, epilepsy, migraine, schizophrenia, anxiety / depression, bipolar disorders, panic, PTSD, Parkinson’s disease / other neurological disorders (MS/ALS/HD/fragile X), irritable bowel syndrome, acromegaly, gastroenteropancreatic and other tumors, hypertension, pulmonary hypertension. PET and other imaging approaches / radiotherapy / electrophysiology / sleep EEG, gene expression profiling, proteomics, SiRNA, epigenetics of mental retardation & Autism Spectrum Disorders. Molecular targets characterised: Monoamine receptors and transporters: 5-HT receptors (all except 5-HT5 and 5-HT6), adrenoceptors (alpha1,2 and beta1,2), dopamine (D2, D3 and D4), 5-HTT, NET, DAT. Peptide and other receptors: Orexin, somatostatin (sst1-sst5), endothelin, CRF, NPS, NPY1,2, neurokinin NK1, sphingolipid S1P1-5, Glutamate (mGluR5, 7), GABAB. Ligand-gated channels and other receptors: 5-HT3, Glutamate (AMPA, Kainate, NMDA), Nicotinic (alpha4beta2, alpha7), GABAA and peripheral benzodiazepine receptors, FMR1 and FMRP.
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