Florian Markowetz holds degrees in Mathematics and Philosophy from University of Heidelberg and a PhD in Computational Biology from Free University Berlin. He was affiliated with the German Cancer Research Center (DKFZ) in Heidelberg and the Max Planck Institute for Molecular Genetics in Berlin. The Max Planck Society honoured his PhD thesis with an Otto-Hahn medal. He pursued post-doctoral research at Princeton University at the Lewis-Sigler Institute for Integrative Genomics. Since 01/2009 he is a group leader at the CRUK Cambridge Institute at the University of Cambridge. In 2014 he was promoted to tenured senior group leader.
Using experimentation, computation and theory, his lab characterizes the influence of genomic variation on patient phenotypes (like survival) and intermediate phenotypes (like gene expression, transcription factor binding or tissue architecture).