Transcriptome alterations induced by cigarette smoke.
Interaction of cigarette exposure and airway epithelial cell gene expression.
Airway PI3K pathway activation is an early and reversible event in lung cancer development.
Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers.
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium.
The field of tissue injury in the lung and airway.
Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium.
Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer.
Microsensor arrays for saliva diagnostics.
Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression.
State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer.
SIEGE: Smoking Induced Epithelial Gene Expression Database.
Gene expression profiling of human lung tissue from smokers with severe emphysema.
Effects of cigarette smoke on the human airway epithelial cell transcriptome.
Impact of cigarette smoke on the normal airway transcriptome.
Noninvasive method for obtaining RNA from buccal mucosa epithelial cells for gene expression profiling.
"What we've got here is a failure to communicate".
The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.
Gene expression in lung adenocarcinomas of smokers and nonsmokers.
Patterns of allelic loss differ in lung adenocarcinomas of smokers and nonsmokers.
Oligonucleotide microarray analysis of lung adenocarcinoma in smokers and nonsmokers identifies GPC3 as a potential lung tumor suppressor.
Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription.
Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer.
FGF-2 induces surfactant protein gene expression in foetal rat lung epithelial cells through a MAPK-independent pathway.
Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion.
FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium.
Epithelial marker genes are expressed in cultured embryonic rat lung and in vivo with similar spatial and temporal patterns.
Retinoic acid alters the expression of pattern-related genes in the developing rat lung.
Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels.
Two closely related receptor-type tyrosine phosphatases are differentially expressed during rat lung development.
Expression of insulin-like growth factor receptors 1 and 2 in the developing lung and their relation to epithelial cell differentiation.
Retinoic acid induces changes in the pattern of airway branching and alters epithelial cell differentiation in the developing lung in vitro.
Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.
Cloning, characterization, and development expression of a rat lung alveolar type I cell gene in embryonic endodermal and neural derivatives.
Insulin-like growth factors, their binding proteins, and transforming growth factor-beta 1 in oxidant-arrested lung alveolar epithelial cells.
Type I collagen formation in rat type II alveolar cells immortalised by viral gene products.
Effect of floating a gel matrix on mucin release in cultured airway epithelial cells.
Inhibition of lung epithelial cell proliferation by hyperoxia. Posttranscriptional regulation of proliferation-related genes.
Pulmonary alveolar epithelial cell differentiation.
A rat alveolar type II cell line developed by adenovirus 12SE1A gene transfer.
SV40T-immortalized lung alveolar epithelial cells display post-transcriptional regulation of proliferation-related genes.
Lung development: past, present and future.
Growth-related gene expression in type 2 alveolar epithelial cells.
Serum accelerates the loss of type II cell differentiation in vitro.
[3H]thymidine incorporation does not correlate with growth state in cultured alveolar type II cells.
Ontogeny of pulmonary alveolar epithelial markers of differentiation.
Constitutive expression of growth-related mRNAs in proliferating and nonproliferating lung epithelial cells in primary culture: evidence for growth-dependent translational control.
Discovery of the cystic fibrosis gene: the interface of basic science and clinical medicine.
Mechanisms of airway goblet cell mucin release: studies with cultured tracheal surface epithelial cells.
Alveolar cell differentiation markers in human lungs.
Use of primary cell culture to study regulation of airway surface epithelial mucus secretion.
Off and running: a progress report from the AJRCMB.
The pattern of cytokeratin synthesis is a marker of type 2 cell differentiation in adult and maturing fetal lung alveolar cells.
Human pulmonary alveolar type 2 cells contain an apical membrane glycoprotein common to malignant cells.
Identification and characterization of the pulmonary alveolar type II cell Maclura pomifera agglutinin-binding membrane glycoprotein.
Characterization of extended primary and secondary cultures of hamster tracheal epithelial cells.
NHLBI workshop summary. Postnatal lung development in health and disease.
Membrane differentiation markers of airway epithelial secretory cells.
Human neutrophil elastase releases cell surface mucins from primary cultures of hamster tracheal epithelial cells.
Lung cell differentiation.
Ultrastructural immunolocalization of lysyl oxidase in vascular connective tissue.
The lipid interstitial cell of the pulmonary alveolus. Age and species differences.
Alveolar wall basement membranes in bleomycin-induced pulmonary fibrosis.
Cell-to-cell interactions in lung development.
Isolation and characterization of a rat lung fraction enriched in alveolar wall basement membranes.
Rehabilitation of ventilator-dependent subjects with lung diseases. The concept and initial experience.
Influence of maternal diabetes on basement membranes, type 2 cells, and capillaries in the developing rat lung.
Binding of charged ferritin to alveolar wall components and charge selectivity of macromolecular transport in permeability pulmonary edema in rats.
In vitro characteristics of the lipid-filled interstitial cell associated with postnatal lung growth: evidence for fibroblast heterogeneity.
Proliferation of alveolar interstitial cells during postnatal lung growth. Evidence for two distinct populations of pulmonary fibroblasts.
Alterations in lung basement membrane during fetal growth and type 2 cell development.
Alterations in alveolar basement membranes during postnatal lung growth.
Determinants of mechanical properties of rat lung during postnatal development.
Structural features of alveolar wall basement membrane in the adult rat lung.
Isolation and characterization of the lipid-containing interstitial cell from the developing rat lung.
Changes in brain surface pH during acute isocapnic metabolic acidosis and alkalosis.
Influence of methylprednisolone on mouse alveolar type 2 cell response to acute lung injury.
Back to back autoradiography: a method for ultrastructural analysis of light microscopic autoradiographs.
Lung lysyl oxidase activity: relation to lung growth.
Leukocyte larceny: a cause of spurious hypoxemia.
Ultrastructural localization and characterization of proteoglycans in the pulmonary alveolus.
Postnatal formation of alveoli: interstitial events and physiologic consequences.
Ultrastructure of developing alveoli. I. The role of the interstitial fibroblast.
Patterns of pulmonary involvement in systemic amyloidosis.
Localized amyloidosis of the lower respiratory tract.
Regulation of breathing in newborns at high altitude.
Deoxyribonucleic acid synthesis in lung cells during compensatory lung growth after pneumonectomy.
Tobacco smolders on.
Lung elasticity and airway dynamics in Peruvian natives to high altitude.
Clinical and roentgenographic spectrum of pulmonary tuberculosis in the adult.
Airway function in sarcoidosis.
Regional bronchoconstriction in asthma. 133Xenon washout scans following parenteral methacholine.
Relative role of environmental and genetic factors in respiratory adaptation to high altitude.
Lung lysyl oxidase and elastin synthesis during compensatory lung growth.
Time course of and stimuli to compensatory growth of the lung after pneumonectomy.
Lung growth induced by hypoxia.
Hormonal influence on post-pneumonectomy lung growth in the rat.
Compensatory growth of the lung following pneumonectomy.
The small lung of hypopituitarism.
Pulmonary function studies during a 14-day continuous exposure to 5.2 per cent O 2 in N 2 at pressure equivalent to 100 FSW (4 ATA).
Hormone-induced growth of the adult lung.
Effect of artificial airway obstruction on elastic properties of the lung.
Mucociliary clearance after lung denervation and bronchial transection.
Restoration of systemic blood flow to the lung after division of bronchial arteries.
Factors influencing function of the autotransplanted lung.
Acromegalic pneumonomegaly: lung growth in the adult.
Idiopathic alveolar hypoventilation: clinical spectrum.
Longitudinal distribution of vascular resistance in the pulmonary arteries, capillaries, and veins.
Differential reactivity in the pulmonary circulation.
The effect of position on pulmonary function in chronic obstructive lung disease.
Subclinical pulmonary emphysema. Incidence and anatomic patterns.