Calogero Raffaele

ORCID iD
https://orcid.org/0000-0002-2848-628X
  • Keywords
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transcriptomics, next generation sequences

Sources:
Calogero Raffaele (2013-03-08)

  • Websites
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B&Gu web page

Sources:
Calogero Raffaele (2015-09-10)

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Scopus Author ID: 7004035394

Sources:
Scopus - Elsevier (2015-09-10)

Biography

EDUCATION: 1984: Laurea in Biological Sciences summa cum laude from Naples University "Federico II" (Italy). 1984-1985: Post-laurea training at Institute of Genetics, General and Molecular Biology (Naples University "Federico II"). 1985-1988: Fellowship at Max Plank Institute fuer Molekulare Genetik in Berlin (Germany). PROFESSIONAL EXPERIENCES: 1989-1992: Researcher at SORIN Biomedica S.p.A. (I). 1992-1998: Associate Professor of Molecular Biology, at Naples University "Federico II". 1998-present: Associate Professor of Molecular Biology at University of Torino. CONSULTANCY ACTIVITIES: 2004-2008: Consultant for the microarray program (AXXAM S.r.l, Milano, I) 2005-2009: Consultant for the microarray program (Nerviano Medical Sciences S.r.l, Nerviano, MI, I) 2010-2013: Consultant for Next generation sequencing application in QC (RBM SERONO, IVREA, I) RESEARCH INTERESTS: 1985 to 1988 As research fellow, At Max Plank Institute, R.A. Calogero was involved in studies concerning the mechanism of initiation of protein synthesis in E. coli. His work allows the definition of the importance of Shine Dalgarno sequence in protein synthesis initiation. 1989 to 1992 As researcher at SORIN Biomedica, R.A. Calogero has worked on protein expression and on the mechanisms involved in RNA-protein interactions in viral genomes (HIV, HCV, HDV). He has set up a lab for protein expression in heterologous systems (Bacteria, Yeast, Insect cells) and purification. An important topic of his work was the expression in heterologous systems, purification of Hepatitis delta antigen and the study of his influence on the interaction with the viral genome. 1992 to 1998 As associate professor of Molecular Biology at Naples University, prof. Calogero has set up a molecular biology/bioinformatics lab at the Dept. of Genetics, Molecular and General Biology in Naples. The focus of the lab was the use of high-throughput approaches to investigate the functionality of peptides able to interfere with the replication cycle of HIV-1 and to develop innovative prokaryotic expression systems. The bioinformatics group was mainly involved in studies on transcription control. 1998-present As associate professor at Medicine School at Torino University, prof. Calogero has set the Genomics and Bioinformatics unit (B&Gu). B&Gu is an interdisciplinary group devoted to the study of multifactorial diseases by mean of high throughput technologies - i.e. microarray, Next Generation Sequencing – and bioinformatics. B&Gu.The main focus of B&Gu are: Identification of biomarkers in the area of oncology and complex diseases. Definition of control mechanisms of carcinogenesis modulated by miRNAs. Developing analytical methods for next generation sequencing applied to RNA-seq Furthermore, B&Gu is involved in research collaborations with university and industry for microarray and NGS data analysis and mining.
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