Gallstone disease: pathogenesis and management.
Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques.
Temperature-dependent 13C nuclear magnetic resonance studies of human serum low density lipoproteins.
Surface pressure-dependent conformation change of apolipoprotein-derived amphipathic a-helices.
Changes in helical content or net charge of apolipoprotein C-I alter its affinity for lipid/water interfaces.
Apoprotein stability and lipid-protein interactions in human plasma high density lipoproteins.
Effects of taurodihydrofusidate, a bile salt analogue, on bile formation and biliary lipid secretion in the rhesus monkey.
Thermal transitions in human plasma low density lipoproteins.
Surface and solution properties of steroid antibiotics: 3-acetoxylfusidic acid, cephalosporin P1 and helvolic acid.
Conformational and thermodynamic properties of apo A-1 of human plasma high density lipoproteins.
The use of phospholipid vesicles for in vitro studies on cholesteryl ester hydrolysis.
The thermal transitions and structural properties of 5alpha-cholestan-3beta-ol esters of aliphatic acids.
Simultaneous measurement of the pancreatic and biliary response to CCK and secretin. Primate biliary physiology. XIII.
A study of the physicochemical interactions between biliary lipids and chlorpromazine hydrochloride. Bile-salt precipitation as a mechanism of phenothiazine-induced bile secretory failure.
Editorial: Hormone use to change normal physiology - is the risk worth it?
Part I. The etiology and pathogenesis of gallstones.
Chemical and physiochemical comparison of advanced atherosclerotic lesions of similar size and cholesterol content in cholesterol-fed New Zealand White and Watanabe Heritable Hyperlipidemic rabbits.
Acyl migration in 1,2-dipalmitoyl-sn-glycerol.
Polymorphic behavior of 1,2-dipalmitoyl-3-lauroyl(PP12)- and 3-myristoyl(PP14)-sn-glycerols.
The distribution of oleic acid between chylomicron-like emulsions, phospholipid bilayers, and serum albumin. A model for fatty acid distribution between lipoproteins, membranes, and albumin.
Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core.
Phase equilibria and structure of dry and hydrated egg lecithin.
Crystal structure of a mixed chain diacylglycerol, 1-stearoyl-3-oleyl-glycerol.
Biophysics of lipid associations. 3. The quaternary systems lecithin-bile salt-cholesterol-water.
Mucin-vesicle interactions in model bile: evidence for vesicle aggregation and fusion before cholesterol crystal formation.
Calorimetry of apolipoprotein-A1 binding to phosphatidylcholine-triolein-cholesterol emulsions.
The physicochemical basis of cholesterol gallstone formation in man.
Physical behavior of the hydrophobic core of membranes: properties of 1-stearoyl-2-linoleoyl-sn-glycerol.
The biophysics of lipidic associations. I. The ternary systems: lecithin-bile salt-water.
Monoacylglycerols alter the lipid composition and molecular mobility of phosphatidylcholine bilayers: 13C NMR evidence of dynamic lipid remodeling.
Ternary and quaternary aqueous systems containing bile salt, lecithin, and cholesterol.
Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells.
Biophysics of lipidic associations. II. The ternary systems: cholesterol-lecithin-water.
Differences in LDL subspecies involve alterations in lipid composition and conformational changes in apolipoprotein B.
Detergent properties of bile salts: correlation with physiological function.
Switch blades, straight performers and distortion by enzymes.
Mechanical properties of model atherosclerotic lesion lipid pools.
Studies on simple and mixed bile salt micelles by nuclear magnetic resonance spectroscopy.
Effects of side chain length on ionization behavior and transbilayer transport of unconjugated dihydroxy bile acids: a comparison of nor-chenodeoxycholic acid and chenodeoxycholic acid.
Micellar properties of dihydroxy and trihydroxy bile salts: effects of counterion and temperature.
The formation of gallstones.
George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry.
The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin.
Secondary and tertiary structure of apolipoproteins.
Mechanisms of reversed cholesterol transport.
Recombinant 52 kDa Ro(SSA) ELISA detects autoantibodies in Sjögren's syndrome sera that go undetected by conventional serologic assays.
Point mutations in the ileal bile salt transporter cause leaks in the enterohepatic circulation leading to severe chronic diarrhea and malabsorption.
Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule.
Cryoelectron microscopy of a nucleating model bile in vitreous ice: formation of primordial vesicles.
Structural analyses of polymorphic transitions of sn-1, 3-distearoyl-2-oleoylglycerol (SOS) and sn-1, 3-dioleoyl-2-stearoylglycerol (OSO): assessment on steric hindrance of unsaturated and saturated acyl chain interactions.
Potpourri: effects of unsaturation on lipid structure; plasma cholesterol ester and lipid-transfer proteins; and cholesterol-sensing proteins and cellular cholesterol movement.
Behavior of tetrahydrolipstatin in biological model membranes and emulsions.
Morphology of sodium deoxycholate-solubilized apolipoprotein B-100 using negative stain and vitreous ice electron microscopy.
Specificity of lipid incorporation is determined by sequences in the N-terminal 37 of apoB.
Physical properties of the transmembrane signal molecule, sn-1-stearoyl 2-arachidonoylglycerol. Acyl chain segregation and its biochemical implications.
Fusions to members of fibroblast growth factor gene family to study nuclear translocation and nonclassic exocytosis.
LIPOPROTEINS OF SYNOVIAL FLUID AS STUDIED BY ANALYTICAL ULTRACENTRIFUGATION.
Physical behavior of lipase substrates.
The effect of triacyl-sn-glycerol structure on the metabolism of chylomicrons and triacylglycerol-rich emulsions in the rat.
The partitioning of fatty acid and cholesterol between core and surfaces of phosphatidylcholine-triolein emulsions at pH 7.4.
Oleic acid allows more apoprotein A-1 to bind with higher affinity to large emulsion particles saturated with cholesterol.
Size and shape determination of fixed chylomicrons and emulsions with fluid or solid surfaces by three-dimensional analysis of shadows.
Interaction of ApoA-1 and ApoE-3 with triglyceride-phospholipid emulsions containing increasing cholesterol concentrations. Model of triglyceride-rich nascent and remnant lipoproteins.
Physico-chemical properties of cholesterol-fed rabbit beta-VLDL are not affected by different dietary oils.
Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters.
The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins.
The sequence of events in gallstone formation.
The lipid composition of drusen, Bruch's membrane, and sclera by hot stage polarizing light microscopy.
Atomic resolution structure analysis of beta' polymorph crystal of a triacylglycerol: 1,2-dipalmitoyl-3-myristoyl-sn-glycerol.
Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps.
The ionization behavior of bile acids in different aqueous environments.
The effect of free cholesterol on the solubilization of cholesteryl oleate in phosphatidylcholine bilayers: A 13C-NMR study.
Surface properties of 1,2-dipalmitoyl-3-acyl-sn-glycerols.
The interfacial properties of ApoA-I and an amphipathic alpha-helix consensus peptide of exchangeable apolipoproteins at the triolein/water interface.
Primate biliary physiology. 8. The effect of phenobarbital upon bile salt synthesis and pool size, biliary lipid secretion, and bile composition.
Interfacial properties of amphipathic beta strand consensus peptides of apolipoprotein B at oil/water interfaces.
Bile composition at and after surgery in normal persons and patients with gallstones. Influence of cholecystectomy.
Solution properties of taurine and glycine conjugates of fusidic acid and its derivatives.
Apolipoprotein B is conformationally flexible but anchored at a triolein/water interface: a possible model for lipoprotein surfaces.
Primate biliary physiology. X. Effects of diet and fasting on biliary lipid secretion and relative composition and bile salt metabolism in the rhesus monkey.
Role of ABC transporters in secretion of cholesterol from liver into bile.
Seasonal variation in plasma lipids, lipoproteins, apolipoprotein A-I and vitellogenin in the freshwater turtle, Chrysemys picta.
Phase behavior and structure of aqueous dispersions of sphingomyelin.
Interfacial properties of an amphipathic alpha-helix consensus peptide of exchangeable apolipoproteins at air/water and oil/water interfaces.
Kos1, a nonreceptor tyrosine kinase that suppresses Ras signaling.
Primate biliary physiology. IX. Effects of acute biliary obstruction on biliary lipid metabolism in the monkey.
The binary phase diagram of lecithin and cholesteryl linolenate.
The ternary phase diagram of lecithin, cholesteryl linolenate and water: phase behavior and structure.
A physiological model to study gallbladder function in primates.
Physical-chemical basis of lipid deposition in atherosclerosis.
Effects of secretin and cholecystokinin on relative composition of hepatic bile in rhesus monkeys.
Transbilayer movement of bile acids in model membranes.
Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites.
Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites.
Effect of free cholesterol on incorporation of triolein in phospholipid bilayers.
Structure and polymorphism of 18-carbon fatty acyl triacylglycerols: effect of unsaturation and substitution in the 2-position.
Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782).
Lateral chain packing in lipids and membranes.
The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field.
Identification and detection of in situ cellular and regional differences of lipid composition and class in lipid-rich tissue using hot stage polarizing light microscopy.
The N-terminal (1-44) and C-terminal (198-243) peptides of apolipoprotein A-I behave differently at the triolein/water interface.
The ionization behavior of fatty acids and bile acids in micelles and membranes.
The incidence and clinical significance of nucleophosmin mutations in childhood AML.
Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis.
Interactions of myristic acid with bovine serum albumin: a 13C NMR study.
Reassembled plasma low density lipoproteins. Phospholipid-cholesterol ester-apoprotein B complexes.
Physicochemical characterization of the urinary lipid from humans with nephrotic syndrome.
Prestone gallstone disease--is therapy safe?
The characteristics of mixed micellar solutions with particular reference to bile.
Source of abnormal bile in patients with cholesterol gallstones.
Flow cytometric findings in hemophagocytic lymphohistiocytosis.
Effects of controlled interruption of the enterohepatic circulation of bile salts by biliary diversion and by ileal resection on bile salt secretion, synthesis, and pool size in the rhesus monkey.
Apolipoprotein C-I binds more strongly to phospholipid/triolein/water than triolein/water interfaces: a possible model for inhibiting cholesterol ester transfer protein activity and triacylglycerol-rich lipoprotein uptake.
C-Terminus of Apolipoprotein A-I Removes Phospholipids from a Triolein/Phospholipids/Water Interface, but the N-Terminus Does Not: A Possible Mechanism for Nascent HDL Assembly.
Interfacial properties of apolipoprotein B292-593 (B6.4-13) and B611-782 (B13-17). Insights into the structure of the lipovitellin homology region in apolipoprotein B.
Adsorption of egg phosphatidylcholine to an air/water and triolein/water bubble interface: use of the 2-dimensional phase rule to estimate the surface composition of a phospholipid/triolein/water surface as a function of surface pressure.
Biliary lipid secretion and bile composition after acute and chronic interruption of the enterohepatic circulation in the Rhesus monkey. IV. Primate biliary physiology.
Localization of fatty acid reesterification in the brush border region of intestinal absorptive cells.
Surface study of apoB1694-1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable.
Effects of alteration of biliary pressure on bile composition--a method for study: primate biliary physiology. V.
Bile composition, bile salt metabolism and gallstones.
Micelle formation by bile salts. Physical-chemical and thermodynamic considerations.
Micellar properties of sodium fusidate, a steroid antibiotic structurally resembling the bile salts.
Gallstones: diagnosis and treatment.
Molecular motions and thermotropic phase behavior of cholesteryl esters with triolein.
Recombinant lipoproteins: implications for structure and assembly of native lipoproteins.
Synthesis and polymorphism of 3-acyl-sn-glycerols.
Structure and polymorphism of 1,2-dioleoyl-3-acyl-sn-glycerols. Three- and six-layered structures.
Physical properties of cholesteryl esters.
Surface-to-core and interparticle equilibrium distributions of triglyceride-rich lipoprotein lipids.
Solubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles.
Lipid digestion and absorption.
Triolein-cholesteryl oleate-cholesterol-lecithin emulsions: structural models of triglyceride-rich lipoproteins.
Transluminal angioplasty in experimental atherosclerosis. Analysis for embolization using an in vivo perfusion system.
Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study.
Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study.
Relationship of an abnormal plasma lipoprotein to protection from atherosclerosis in the cholesterol-fed diabetic rabbit.
1H NMR studies of lymph chylomicra and very low density lipoproteins from nonhuman primates.
Cholesterol content of red blood cells and low-density lipoproteins in hypertriglyceridemia.
Microemulsions of phospholipids and cholesterol esters. Protein-free models of low density lipoprotein.
Solubilization and localization of cholesteryl oleate in egg phosphatidylcholine vesicles. A carbon 13 NMR study.
Ionization behavior of aqueous short-chain carboxylic acids: a carbon-13 NMR study.
Physical characterization of lymph chylomicrons and very low density lipoproteins from nonhuman primates fed saturated dietary fat.
Physical studies of d less than 1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets.
Rapid method for determining cholesteryl ester transitions of apoB-containing lipoproteins.
Mobilization of cholesterol from cholesterol ester-enriched tissue culture cells by phospholipid dispersions.
The effect of elevated biliary tract pressure on biliary lipid metabolism and bile flow in nonhuman primates.
National Cooperative Gallstone Study: the effect of chenodeoxycholic acid on lipoproteins and apolipoproteins.
Interaction of oleoyl coenzyme A with phospholipid bilayers.
Cholesterol turnover in lipid phases of human atherosclerotic plaque.
Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study.
The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers.
Fatty acid distribution in systems modeling the normal and diabetic human circulation. A 13C nuclear magnetic resonance study.
The lipid surface of triglyceride-rich particles can modulate (apo)protein binding and tissue uptake.
Chemistry in the kitchen. Making ground meat more healthful.
Plasma clearance of emulsified triolein in conscious rats: effects of phosphatidylcholine species, cholesterol content and emulsion surface physical state.
The effects of glyceride structure on absorption and metabolism.
X-ray diffraction and calorimetric study of anhydrous and hydrated N-palmitoylgalactosylsphingosine (cerebroside).
Structure and polymorphism of saturated monoacid 1,2-diacyl-sn-glycerols.
Effects of lecithin ingestion on plasma and lymph lipoproteins of normo- and hyperlipemic rats.
Organization of the core lipids of high density lipoproteins in the lactating bovine.
Physical properties of cholesteryl esters having 20 carbons or more.
Cholesterol nucleation and growth in gallstone formation.
Isolation and and partial characterization of the lipid phases of human atherosclerotic plaques.
Body cholesterol removal: role of plasma high-density lipoproteins.
X-ray and neutron scattering studies of plasma lipoproteins.
Temperature and compositional dependence of the structure of hydrated dimyristoyl lecithin.
Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B.
A comparison of lipoprotein secretion, bile production and hepatic morphology in isolated rat livers perfused with a perfluorocarbon emulsion or rat erythrocytes.
Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs.
Bovine gallbladder mucin accelerates cholesterol monohydrate crystal growth in model bile.
Mutation of the cyclin-dependent kinase phosphorylation site in simian virus 40 (SV40) large T antigen specifically blocks SV40 origin DNA unwinding.
Physical behavior of the mixed chain diacylglycerol, 1-stearoyl-2-oleoyl-sn-glycerol: difficulties in chain packing produced marked polymorphism.
Formation of cholesterol monohydrate crystals in macrophage-derived foam cells.
Filamentous, helical, and tubular microstructures during cholesterol crystallization from bile. Evidence that cholesterol does not nucleate classic monohydrate plates.
Doctor in the kitchen: experiments on sauce Béarnaise.
Single crystal structure of a mixed-chain triacylglycerol: 1,2-dipalmitoyl-3-acetyl-sn-glycerol.
The phase behavior of hydrated cholesterol.
Do dietary fatty acids affect the biophysics of platelet-membrane function in thrombosis?
Quantitation of the transfer of surface phospholipid of chylomicrons to the high density lipoprotein fraction during the catabolism of chylomicrons in the rat.
1992 Aspen Bile Acid/Cholesterol/Lipoprotein Conference. Report of a conference.
Studies on the structure of low density lipoproteins isolated from Macaca fascicularis fed an atherogenic diet.
Lectin-induced agglutination of phospholipid/glycolipid vesicles.
Effects of chlorpromazine hydrochloride on bile salt synthesis, bile formation and biliary lipid secretion in the rhesus monkey: a model for chlorpromazine-induced cholestasis.
Interactions of cholesterol esters with phospholipids: cholesteryl myristate and dimyristoyl lecithin.
Structural organization of the lipoprotein HDLc from atherosclerotic swine. Structural features relating the particle surface and core.
Interaction of collagen with the lipids of tendon xanthomata.
Plasma high-density lipoproteins.
Phase behavior and structural characteristics of hydrated bovine brain gangliosides.
The storage lipids in Tangier disease. A physical chemical study.
Cellular mechanisms for lipid deposition in atherosclerosis (second of two parts).
Characterization of the lipoproteins of atherosclerotic swine.
Cellular mechanisms for lipid deposition in atherosclerosis (first of two parts).
Structure and thermodynamic properties of high density lipoprotein recombinants.
The dissolution of cholesterol monohydrate crystals in atherosclerotic plaque lipids.
Structural effects of myelin proteolipid apoprotein on phospholipids: a Raman spectroscopic study.
The physical chemistry of cholesterol solubility in bile. Relationship to gallstone formation and dissolution in man.
Interaction of plasma high density lipoproteins with dimyristoyllecithin multilamellar liposomes.
Nature of the Thermal pretransition of synthetic phospholipids: dimyristolyl- and dipalmitoyllecithin.
Structure and interactions of lipids in human plasma low density lipoproteins.
Solubilisation of phospholipid membranes by human plasma high density lipoproteins.
Structure of human plasma low-density lipoproteins: molecular organization of the central core.
Interaction of cholesterol ester and triglyceride in human plasma very low density lipoprotein.
Production of cholesteryl ester-rich, anisotropic inclusions by mammalian cells in culture.
Failure of complete bile diversion and oral bile acid therapy in the treatment of homozygous familial hypercholesterolemia.
Biliary lipid secretion in cholesterol gallstone disease. The effect of cholecystectomy and obesity.
Thermal behavior of human plasma high density lipoprotein.
Protein-lipid interactions: recombinants of the proteolipid apoprotein of myelin with dimyristoyllecithin.