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Activities

Employment (3)

University of Oxford: Oxford, Oxfordshire, GB

2019-07 to 2020-08 | Postdoctoral Research Scientist (Nuffield Department of Medicine)
Employment
Source: Self-asserted source
Fergus Poynton

Trinity College Dublin: Dublin, Leinster, IE

2019 to 2019 | Postdoctoral Research Fellow (Chemistry)
Employment
Source: Self-asserted source
Fergus Poynton

Trinity College Dublin: Dublin, IE

2017 to 2018 | Postdoctoral Research Fellow (Clinical Medicine and Chemistry)
Employment
Source: Self-asserted source
Fergus Poynton

Education and qualifications (2)

University of Dublin Trinity College: Dublin, IE

2011-10 to 2016-05 | PhD (School of Chemistry)
Education
Source: Self-asserted source
Fergus Poynton

University of Dublin Trinity College: Dublin, IE

2007-10 to 2011-05 | B.A. Mod. in Chemistry (School of Chemistry)
Education
Source: Self-asserted source
Fergus Poynton

Works (14)

Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics

Physical Chemistry Chemical Physics
2022 | Journal article
Part of ISSN: 1463-9076
Part of ISSN: 1463-9084
Contributors: Paraic Keane; Clara Maria Irene Zehe; Fergus E. Poynton; Sandra A. Bright; Sandra Estalayo-Adrián; Stephen J. Devereux; Paul Donaldson; Igor Sazanovich; Michael Towrie; Stanley W. Botchway et al.
Source: Self-asserted source
Fergus Poynton

Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with polydeoxynucleotides and mixed sequence oligodeoxynucleotides

Chemical Science
2020 | Journal article
Part of ISSN: 2041-6520
Part of ISSN: 2041-6539
Contributors: Paraic Keane; Kyra O'Sullivan; Fergus E. Poynton; Bjørn C. Poulsen; Igor V. Sazanovich; Michael Towrie; Christine J. Cardin; Xue-Zhong Sun; Michael George; Thorfinnur Gunnlaugsson et al.
Source: Self-asserted source
Fergus Poynton

Caught in the Loop: Binding of the [Ru(phen) <sub>2</sub> (dppz)] <sup>2+</sup> Light‐Switch Compound to Quadruplex DNA in Solution Informed by Time‐Resolved Infrared Spectroscopy

Chemistry – A European Journal
2020-12-18 | Journal article
Part of ISSN: 0947-6539
Part of ISSN: 1521-3765
Contributors: Stephen J. Devereux; Fergus E. Poynton; Frederico R. Baptista; Thorfinnur Gunnlaugsson; Christine J. Cardin; Igor V. Sazanovich; Michael Towrie; John Kelly; Susan Quinn
Source: Self-asserted source
Fergus Poynton

Nanotechnology based therapeutics for lung disease

Thorax
2019-07-08 | Journal article
Source: Self-asserted source
Fergus Poynton

Inosine Can Increase DNA′s Susceptibility to Photo-oxidation by a RuII Complex due to Structural Change in the Minor Groove

Chemistry – A European Journal
2017 | Journal article
Contributors: Keane, Páraic M.; Hall, James P.; Poynton, Fergus E.; Poulsen, Bjørn C.; Gurung, Sarah P.; Clark, Ian P.; Sazanovich, Igor V.; Towrie, Michael; Gunnlaugsson, Thorfinnur; Quinn, Susan J. et al.
Source: Self-asserted source
Fergus Poynton via ResearcherID

The development of ruthenium(ii) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications

Chemical Society Reviews
2017 | Journal article
Contributors: Fergus E. Poynton; Sandra A. Bright; Salvador Blasco; D. Clive Williams; John M. Kelly; Thorfinnur Gunnlaugsson
Source: check_circle
Crossref

Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)(2)(dppz)](2+) light-switch compound in solution and when bound to DNA

Chemical Science
2016 | Journal article
WOSUID:

WOS:000374859300015

Contributors: Poynton, Fergus E.; Hall, James P.; Keane, Paraic M.; Schwarz, Christine; Sazanovich, Igor V.; Towrie, Michael; Gunnlaugsson, Thorfinnur; Cardin, Christine J.; Cardin, David J.; Quinn, Susan J. et al.
Source: Self-asserted source
Fergus Poynton via ResearcherID

Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells

Journal of Medicinal Chemistry
2015 | Journal article
WOSUID:

WOS:000356316600007

Contributors: Cloonan, Suzanne M.; Elmes, Robert B. P.; Erby, MariaLuisa; Bright, Sandra A.; Poynton, Fergus E.; Nolan, Derek E.; Quinn, Susan J.; Gunnlaugsson, Thorfinnur; Williams, D. Clive
Source: Self-asserted source
Fergus Poynton via ResearcherID

Enantiomeric Conformation Controls Rate and Yield of Photoinduced Electron Transfer in DNA Sensitized by Ru(II) Dipyridophenazine Complexes

Journal of Physical Chemistry Letters
2015 | Journal article
WOSUID:

WOS:000349942500011

Contributors: Keane, Paraic M.; Poynton, Fergus E.; Hall, James P.; Clark, Ian P.; Sazanovich, Igor V.; Towrie, Michael; Gunnlaugsson, Thorfinnur; Quinn, Susan J.; Cardin, Christine J.; Kelly, John M.
Source: Self-asserted source
Fergus Poynton via ResearcherID

Monitoring guanine photo-oxidation by enantiomerically resolved Ru(II) dipyridophenazine complexes using inosine-substituted oligonucleotides

Faraday Discussions
2015 | Journal article
WOSUID:

WOS:000366909400025

Contributors: Keane, Paraic M.; Poynton, Fergus E.; Hall, James P.; Clark, Ian P.; Sazanovich, Igor V.; Towrie, Michael; Gunnlaugsson, Thorfinnur; Quinn, Susan J.; Cardin, Christine J.; Kelly, John M.
Source: Self-asserted source
Fergus Poynton via ResearcherID

Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy

Nature Chemistry
2015 | Journal article
WOSUID:

WOS:000365279200009

Contributors: Hall, James P.; Poynton, Fergus E.; Keane, Paraic M.; Gurung, Sarah P.; Brazier, John A.; Cardin, David J.; Winter, Graeme; Gunnlaugsson, Thorfinnur; Sazanovich, Igor V.; Towrie, Michael et al.
Source: Self-asserted source
Fergus Poynton via ResearcherID

Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex.

Angewandte Chemie (International ed. in English)
2015 | Journal article
WOSUID:

MEDLINE:26096623

Contributors: Keane, Paraic M; Poynton, Fergus E; Hall, James P; Sazanovich, Igor V; Towrie, Michael; Gunnlaugsson, Thorfinnur; Quinn, Susan J; Cardin, Christine J; Kelly, John M
Source: Self-asserted source
Fergus Poynton via ResearcherID

Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(II)-polypyridyl conjugates

Dalton Transactions
2015 | Journal article
WOSUID:

WOS:000361544500018

Contributors: Ryan, Gary J.; Poynton, Fergus E.; Elmes, Robert B. P.; Erby, Marialuisa; Williams, D. Clive; Quinn, Susan J.; Gunnlaugsson, Thorfinnur
Source: Self-asserted source
Fergus Poynton via ResearcherID

Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Troger's bases

Organic &amp; Biomolecular Chemistry
2014 | Journal article
WOSUID:

WOS:000341021400011

Contributors: Murphy, Samantha; Bright, Sandra A.; Poynton, Fergus E.; McCabe, Thomas; Kitchen, Jonathan A.; Veale, Emma B.; Williams, D. Clive; Gunnlaugsson, Thorfinnur
Source: Self-asserted source
Fergus Poynton via ResearcherID