Conformations and orientations of a signal peptide interacting with phospholipid monolayers.
Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Helix formation and stability in a signal sequence.
Biophysical studies of signal peptides: implications for signal sequence functions and the involvement of lipid in protein export.
Sequence-specific DNA binding by a short peptide dimer.
Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region.
Minimum length of a sequence-specific DNA binding peptide.
A thermostable 35-residue subdomain within villin headpiece.
NMR structure of the 35-residue villin headpiece subdomain.
Evolution of a protein fold in vitro.
NMR structure of an F-actin-binding "headpiece" motif from villin.
An evolutionary bridge to a new protein fold.
The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins.
Zinc and copper bind to unique sites of histatin 5.
The role of aromatic residues in the hydrophobic core of the villin headpiece subdomain.
Villin-type headpiece domains show a wide range of F-actin-binding affinities.
Temperature-dependent dynamics of the villin headpiece helical subdomain, an unusually small thermostable protein.
A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia.
Solution structure of switch Arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon.
Dynamic NMR line-shape analysis demonstrates that the villin headpiece subdomain folds on the microsecond time scale.
The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site.
Limited proteolysis and biophysical characterization of the lipovitellin homology region in apolipoprotein B.
High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Networking at the Protein Society symposium.
Multistate folding of the villin headpiece domain.
Characterizing a partially folded intermediate of the villin headpiece domain under non-denaturing conditions: contribution of His41 to the pH-dependent stability of the N-terminal subdomain.
A phosphorylation-induced conformation change in dematin headpiece.
Defining lipid-interacting domains in the N-terminal region of apolipoprotein B.
Structural analysis of reconstituted lipoproteins containing the N-terminal domain of apolipoprotein B.
The isolated sixth gelsolin repeat and headpiece domain of villin bundle F-actin in the presence of calcium and are linked by a 40-residue unstructured sequence.
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Missense mutations in APOB within the betaalpha1 domain of human APOB-100 result in impaired secretion of ApoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia.
The differential impact of disulfide bonds and N-linked glycosylation on the stability and function of CD14.
Crystal structure of a pH-stabilized mutant of villin headpiece.
Reconstituting initial events during the assembly of apolipoprotein B-containing lipoproteins in a cell-free system.
Slow motions in chicken villin headpiece subdomain probed by cross-correlated NMR relaxation of amide NH bonds in successive residues.
Phosphorylation-induced changes in backbone dynamics of the dematin headpiece C-terminal domain.
Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782).
Dematin exhibits a natively unfolded core domain and an independently folded headpiece domain.
A novel missense HGD gene mutation, K57N, in a patient with alkaptonuria.
Heterogeneity and dynamics in villin headpiece crystal structures.
How to arm a supervillin: designing F-actin binding activity into supervillin headpiece.
Identifying competitive protein antagonists for F-actin with reverse-phase high-performance liquid chromatography.
Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B.
Molecular model of the microvillar cytoskeleton and organization of the brush border.
Interfacial properties of apolipoprotein B292-593 (B6.4-13) and B611-782 (B13-17). Insights into the structure of the lipovitellin homology region in apolipoprotein B.
Competition between Intradomain and Interdomain Interactions: A Buried Salt Bridge Is Essential for Villin Headpiece Folding and Actin Binding.
On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece.
Intraocular ophthalmic ointment following anterior segment surgery.
Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells.
On the unyielding hydrophobic core of villin headpiece.
The Allosteric Mechanism Induced by Protein Kinase A (PKA) Phosphorylation of Dematin (Band 4.9).
IcmQ in the Type 4b Secretion System Contains an NAD(+) Binding Domain.