Helix formation and stability in a signal sequence.
Dematin exhibits a natively unfolded core domain and an independently folded headpiece domain.
Biophysical studies of signal peptides: implications for signal sequence functions and the involvement of lipid in protein export.
Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782).
Heterogeneity and dynamics in villin headpiece crystal structures.
A novel missense HGD gene mutation, K57N, in a patient with alkaptonuria.
Reconstituting initial events during the assembly of apolipoprotein B-containing lipoproteins in a cell-free system.
Crystal structure of a pH-stabilized mutant of villin headpiece.
Conformations and orientations of a signal peptide interacting with phospholipid monolayers.
Phosphorylation-induced changes in backbone dynamics of the dematin headpiece C-terminal domain.
Functional and nonfunctional LamB signal sequences can be distinguished by their biophysical properties.
Slow motions in chicken villin headpiece subdomain probed by cross-correlated NMR relaxation of amide NH bonds in successive residues.
Identifying competitive protein antagonists for F-actin with reverse-phase high-performance liquid chromatography.
How to arm a supervillin: designing F-actin binding activity into supervillin headpiece.
Nonsynonymous mutations within APOB in human familial hypobetalipoproteinemia: evidence for feedback inhibition of lipogenesis and postendoplasmic reticulum degradation of apolipoprotein B.
The Allosteric Mechanism Induced by Protein Kinase A (PKA) Phosphorylation of Dematin (Band 4.9).
On the unyielding hydrophobic core of villin headpiece.
Identification of a specific region of Plasmodium falciparum EBL-1 that binds to host receptor glycophorin B and inhibits merozoite invasion in human red blood cells.
The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins.
Intraocular ophthalmic ointment following anterior segment surgery.
On unsatisfied hydrogen bonds in the N-terminal subdomain of villin headpiece.
NMR structure of an F-actin-binding "headpiece" motif from villin.
Competition between Intradomain and Interdomain Interactions: A Buried Salt Bridge Is Essential for Villin Headpiece Folding and Actin Binding.
An evolutionary bridge to a new protein fold.
Interfacial properties of apolipoprotein B292-593 (B6.4-13) and B611-782 (B13-17). Insights into the structure of the lipovitellin homology region in apolipoprotein B.
NMR structure of the 35-residue villin headpiece subdomain.
Molecular model of the microvillar cytoskeleton and organization of the brush border.
Evolution of a protein fold in vitro.
Minimum length of a sequence-specific DNA binding peptide.
A thermostable 35-residue subdomain within villin headpiece.
Fluorescence analysis of tryptophan-containing variants of the LamB signal sequence upon insertion into a lipid bilayer.
Conformational and membrane-binding properties of a signal sequence are largely unaltered by its adjacent mature region.
Sequence-specific DNA binding by a short peptide dimer.
IcmQ in the Type 4b Secretion System Contains an NAD(+) Binding Domain.
The role of aromatic residues in the hydrophobic core of the villin headpiece subdomain.
Zinc and copper bind to unique sites of histatin 5.
Temperature-dependent dynamics of the villin headpiece helical subdomain, an unusually small thermostable protein.
Villin-type headpiece domains show a wide range of F-actin-binding affinities.
Solution structure of switch Arc, a mutant with 3(10) helices replacing a wild-type beta-ribbon.
A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia.
The NMR structure of dematin headpiece reveals a dynamic loop that is conformationally altered upon phosphorylation at a distal site.
Dynamic NMR line-shape analysis demonstrates that the villin headpiece subdomain folds on the microsecond time scale.
High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity.
Limited proteolysis and biophysical characterization of the lipovitellin homology region in apolipoprotein B.
Characterizing a partially folded intermediate of the villin headpiece domain under non-denaturing conditions: contribution of His41 to the pH-dependent stability of the N-terminal subdomain.
Multistate folding of the villin headpiece domain.
Networking at the Protein Society symposium.
The isolated sixth gelsolin repeat and headpiece domain of villin bundle F-actin in the presence of calcium and are linked by a 40-residue unstructured sequence.
Structural analysis of reconstituted lipoproteins containing the N-terminal domain of apolipoprotein B.
Defining lipid-interacting domains in the N-terminal region of apolipoprotein B.
A phosphorylation-induced conformation change in dematin headpiece.
The differential impact of disulfide bonds and N-linked glycosylation on the stability and function of CD14.
Missense mutations in APOB within the betaalpha1 domain of human APOB-100 result in impaired secretion of ApoB and ApoB-containing lipoproteins in familial hypobetalipoproteinemia.
Ligand-induced conformational changes allosterically activate Toll-like receptor 9.