Insider access: pepducin symposium explores a new approach to GPCR modulation.
Mice deficient in phosphofructokinase-M have greatly decreased fat stores.
Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir.
The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome.
Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy.
Early-life sodium exposure unmasks susceptibility to stroke in hyperlipidemic, hypertensive heterozygous Tg25 rats transgenic for human cholesteryl ester transfer protein.
Differential effects of natriuretic peptides on arterial and venous coronary artery bypass conduits.
Grapes and cardiovascular disease.
Incorporation of medium chain triacylglycerols into phospholipid bilayers: effect of long chain triacylglycerols, cholesterol, and cholesteryl esters.
Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice.
Magic-angle spinning and solution 13C nuclear magnetic resonance studies of medium- and long-chain cholesteryl esters in model bilayers.
c-fos antisense DNA inhibits proliferation of osteoclast progenitors in osteoclast development but not macrophage differentiation in vitro.
Monoacylglycerols alter the lipid composition and molecular mobility of phosphatidylcholine bilayers: 13C NMR evidence of dynamic lipid remodeling.
The brachial artery remodels to maintain local shear stress despite the presence of cardiovascular risk factors.
Flexibility is a likely determinant of binding specificity in the case of ileal lipid binding protein.
Binding of ethyl oleate to low density lipoprotein, phospholipid vesicles, and albumin: a 13C NMR study.
Intracellular pH in adipocytes: effects of free fatty acid diffusion across the plasma membrane, lipolytic agonists, and insulin.
Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.
13C MAS NMR studies of crystalline cholesterol and lipid mixtures modeling atherosclerotic plaques.
Granulocyte colony-stimulating factor-stimulated proliferation of myeloid cells: mode of cell cycle control by a range of inhibitors.
A multinuclear solid-state NMR study of phospholipid-cholesterol interactions. Dipalmitoylphosphatidylcholine-cholesterol binary system.
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase.
A robust rabbit model of human atherosclerosis and atherothrombosis.
Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation.
Images in cardiovascular medicine. Healing of an asymptomatic carotid plaque ulceration.
Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.
Fatty acid flip-flop in a model membrane is faster than desorption into the aqueous phase.
Measuring the adsorption of Fatty acids to phospholipid vesicles by multiple fluorescence probes.
Structural requirements for charged lipid molecules to directly increase or suppress K+ channel activity in smooth muscle cells. Effects of fatty acids, lysophosphatidate, acyl coenzyme A and sphingosine.
Fast/Glycolytic muscle fiber growth reduces fat mass and improves metabolic parameters in obese mice.
Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis.
New insights into the roles of proteins and lipids in membrane transport of fatty acids.
Molecular organization and motions of crystalline monoacylglycerols and diacylglycerols: a C-13 MASNMR study.
Direct effects of fatty acids and other charged lipids on ion channel activity in smooth muscle cells.
Changes in internal pH caused by movement of fatty acids into and out of clonal pancreatic beta-cells (HIT).
Effects of side chain length on ionization behavior and transbilayer transport of unconjugated dihydroxy bile acids: a comparison of nor-chenodeoxycholic acid and chenodeoxycholic acid.
Fatty acid flip-flop in phospholipid bilayers is extremely fast.
Interactions of a very long chain fatty acid with model membranes and serum albumin. Implications for the pathogenesis of adrenoleukodystrophy.
Phase behavior and crystalline structures of cholesteryl ester mixtures: a C-13 MASNMR study.
Interactions of lyso 1-palmitoylphosphatidylcholine with phospholipids: a 13C and 31P NMR study.
Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers.
13C NMR studies of the binding of medium-chain fatty acids to human serum albumin.
Protective Role for TLR4 Signaling in Atherosclerosis Progression as Revealed by Infection with a Common Oral Pathogen.
Detection of thrombus size and protein content by ex vivo magnetization transfer and diffusion weighted MRI.
Correspondence of Fatty Acid and drug binding sites on human serum albumin: a two-dimensional nuclear magnetic resonance study.
Regions of low endothelial shear stress colocalize with positive vascular remodeling and atherosclerotic plaque disruption: an in vivo magnetic resonance imaging study.
Healthy obese persons: how can they be identified and do metabolic profiles stratify risk?
Regeneration of antidigoxin binding activity in an antibody by changes surrounding the original binding defect.
Cytokine regulation of granulocyte-macrophage colony stimulating factor and macrophage colony-stimulating factor production in human arterial smooth muscle cells.
Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain.
Molecular organization and motions of cholesteryl esters in crystalline and liquid crystalline phases: a 13C and 1H magic angle spinning NMR study.
Effect of disease progression on liver apparent diffusion coefficient and T(2) values in a murine model of hepatic fibrosis at 11.7 Tesla MRI.
Plasminogen activator in granulocyte-macrophage-CSF transgenic mice.
pH gradients across phospholipid membranes caused by fast flip-flop of un-ionized fatty acids.
Solution structure and backbone dynamics of human liver Fatty Acid binding protein: Fatty Acid binding revisited.
The x-ray crystal structure refinements of normal human transthyretin and the amyloidogenic Val-30-->Met variant to 1.7-A resolution.
Magnetization transfer magnetic resonance of human atherosclerotic plaques ex vivo detects areas of high protein density.
NMR studies of phospholipase C hydrolysis of phosphatidylcholine in model membranes.
Interfacial conformation of dipalmitoylglycerol and dipalmitoylphosphatidylcholine in phospholipid bilayers.
Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin.
Inhibition of S-phase progression in macrophages is linked to G1/S-phase suppression of DNA synthesis genes.
Porphyromonas gingivalis accelerates inflammatory atherosclerosis in the innominate artery of ApoE deficient mice.
Enhancing the Contrast of ApoB to Locate the Surface Components in the 3D Density Map of Human LDL.
Caveolins sequester FA on the cytoplasmic leaflet of the plasma membrane, augment triglyceride formation, and protect cells from lipotoxicity.
In vivo detection of vulnerable atherosclerotic plaque by MRI in a rabbit model.
Study of the miscibility of cholesteryl oleate in a matrix of ceramide, cholesterol and fatty acid.
Application of MRI to detect high-risk atherosclerotic plaque.
Effect of disease progression on liver apparent diffusion coefficient values in a murine model of NASH at 11.7 tesla MRI.
Effects of acetaldehyde on hepatocyte glycerol uptake and cell size: implication of aquaporin 9.
Profound increase in viscosity and aggregation of pig gastric mucin at low pH.
Transforming growth factor beta stimulates urokinase-type plasminogen activator and DNA synthesis, but not prostaglandin E2 production, in human synovial fibroblasts.
Conformation and inhibitory properties of peptides based on the tissue kallikrein-aprotinin complex.
Solubilization and localization of weakly polar lipids in unsonicated egg phosphatidylcholine: A 13C MAS NMR study.
Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.
Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin.
Fatty acids are rapidly delivered to and extracted from membranes by methyl-beta-cyclodextrin.
The interfacial conformation and transbilayer movement of diacylglycerols in phospholipid bilayers.
A V kappa-J kappa junctional change in an antidigoxin recombinant antibody destroys digoxin-binding activity.
How fatty acids bind to proteins: the inside story from protein structures.
A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems.
Interactions of acyl carnitines with model membranes: a (13)C-NMR study.
Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins?
Na+/H+ exchange involvement in colony-stimulating factor-1-stimulated macrophage proliferation. Evidence for a requirement during late G1 of the cell cycle but not for early growth factor responses.
Medium-chain fatty acid binding to albumin and transfer to phospholipid bilayers.
Hydrolysis of a phospholipid in an inert lipid matrix by phospholipase A2: a 13C NMR study.
Fatty acid transport: the diffusion mechanism in model and biological membranes.
Medium-chain versus long-chain triacylglycerol emulsion hydrolysis by lipoprotein lipase and hepatic lipase: implications for the mechanisms of lipase action.
Tissue-type plasminogen activator deficiency exacerbates arthritis.
The distribution of oleic acid between chylomicron-like emulsions, phospholipid bilayers, and serum albumin. A model for fatty acid distribution between lipoproteins, membranes, and albumin.
Colony-stimulating factor-1 (CSF-1) receptor-mediated macrophage differentiation in myeloid cells: a role for tyrosine 559-dependent protein phosphatase 2A (PP2A) activity.
The ionization and distribution behavior of oleic acid in chylomicrons and chylomicron-like emulsion particles and the influence of serum albumin.
In vivo magnetic resonance imaging of experimental thrombosis in a rabbit model.
Interactions of oleic acid with liver fatty acid binding protein: a carbon-13 NMR study.
Transthyretin: a review from a structural perspective.
Ionization and phase behavior of fatty acids in water: application of the Gibbs phase rule.
Interactions of very long-chain saturated fatty acids with serum albumin.
Interactions of triglycerides with phospholipids: incorporation into the bilayer structure and formation of emulsions.
Secondary and tertiary structure of apolipoproteins.
Brain uptake and utilization of fatty acids: applications to peroxisomal biogenesis diseases.
Brain uptake and utilization of fatty acids: recommendations for future research.
Binding of 13-HODE and 15-HETE to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins. implications for transmembrane and intracellular transport and for protection from lipid peroxidation.
Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes.
Enhancement of macrophage survival and DNA synthesis by oxidized-low-density-lipoprotein (LDL)-derived lipids and by aggregates of lightly oxidized LDL.
Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. II. Electrostatic interactions in individual fatty acid binding sites.
Temperature-dependent molecular motions and phase behavior of cholesteryl ester analogues.
Partial synthesis and properties of a series of N-acyl sphingomyelins.
Quantification in situ of crystalline cholesterol and calcium phosphate hydroxyapatite in human atherosclerotic plaques by solid-state magic angle spinning NMR.
Carbon 13 NMR studies of saturated fatty acids bound to bovine serum albumin. I. The filling of individual fatty acid binding sites.
The effect of free cholesterol on the solubilization of cholesteryl oleate in phosphatidylcholine bilayers: A 13C-NMR study.
Transbilayer movement of bile acids in model membranes.
Quantification of cholesteryl esters in human and rabbit atherosclerotic plaques by magic-angle spinning (13)C-NMR.
The ionization behavior of bile acids in different aqueous environments.
Glucagon-like peptide 1 stimulates lipolysis in clonal pancreatic beta-cells (HIT).
Phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid-soaps.
Esterification of free fatty acids in adipocytes: a comparison between octanoate and oleate.
Nuclear magnetic resonance studies of lipoproteins.
Oxidized LDL can promote human monocyte survival.
Transfer of oleic acid between albumin and phospholipid vesicles.
Regulation of urokinase plasminogen activator gene transcription in the RAW264 murine macrophage cell line by macrophage colony-stimulating factor (CSF-1) is dependent upon the level of cell-surface receptor.
The ionization behavior of fatty acids and bile acids in micelles and membranes.
Solution structure of ileal lipid binding protein in complex with glycocholate.
Thermotropic properties and molecular dynamics of cholesteryl ester rich very low density lipoproteins: effect of hydrophobic core on polar surface.
Molecular motions and thermotropic phase behavior of cholesteryl esters with triolein.
A comparative study of the backbone dynamics of two closely related lipid binding proteins: bovine heart fatty acid binding protein and porcine ileal lipid binding protein.
Transport of fatty acids across membranes by the diffusion mechanism.
Incorporation of [1-13C]oleate into cellular triglycerides in differentiating 3T3L1 cells.
How are free fatty acids transported in membranes? Is it by proteins or by free diffusion through the lipids?
A 13C nuclear magnetic resonance study of free fatty acid incorporation in acylated lipids in differentiating preadipocytes.
Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice.
Ionization behavior of aqueous short-chain carboxylic acids: a carbon-13 NMR study.
MRL/lpr and MRL+/+ macrophage DNA synthesis in the absence and the presence of colony-stimulating factor-1 and granulocyte-macrophage colony-stimulating factor.
Solubilization and localization of cholesteryl oleate in egg phosphatidylcholine vesicles. A carbon 13 NMR study.
Oxidized LDL can induce macrophage survival, DNA synthesis, and enhanced proliferative response to CSF-1 and GM-CSF.
Temperature-dependent molecular motions of cholesterol esters: a carbon-13 nuclear magnetic resonance study.
1H NMR studies of lymph chylomicra and very low density lipoproteins from nonhuman primates.
Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study.
Solubilization of triolein and cholesteryl oleate in egg phosphatidylcholine vesicles.
Interactions of myristic acid with bovine serum albumin: a 13C NMR study.
Fatty acid transport: difficult or easy?
Physical studies of d less than 1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets.
Streptococcal cell walls and synovial cell activation. Stimulation of synovial fibroblast plasminogen activator activity by monocytes treated with group A streptococcal cell wall sonicates and muramyl dipeptide.
Identification of different lipid phases and calcium phosphate deposits in human carotid artery plaques by MAS NMR spectroscopy.
Lipoprotein-X: carbon-13 nuclear magnetic resonance studies on native, reconstituted, and model systems.
Different pathways of colony-stimulating factor 1 degradation in macrophage populations revealed by wortmannin sensitivity.
Solubilization and localization of triolein in phosphatidylcholine bilayers: a 13C NMR study.
Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid.
G1 phase arrest of human smooth muscle cells by heparin, IL-4 and cAMP is linked to repression of cyclin D1 and cdk2.
Identification of phosphoproteins specific to granulocyte colony-stimulating factor-mediated signaling using 2D-SDS-PAGE.
Solution structure of human intestinal fatty acid binding protein: implications for ligand entry and exit.
Hapten-specific tolerance in mice. II. Adoptive transfer studies and evidence for unresponsiveness in the B cells.
Dissociation of long and very long chain fatty acids from phospholipid bilayers.
High-field 13C NMR Studies of certain normal and abnormal human plasma lipoproteins.
CSF-1 and cell cycle control in macrophages.
Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages.
Molecular dynamics of lipids in human plasma high density lipoproteins. A high field 13C NMR study.
Lipid dynamics in human low density lipoproteins and human aortic tissue with fibrous plaques. A study by high field 13C NMR spectroscopy.
Carbon-13 nuclear magnetic resonance studies of cholesteryl esters and cholesteryl ester/triglyceride mixtures.
Natural abundance 13C nuclear magnetic resonance studies of human plasma high density lipoproteins.
Biochemical and genetic studies on ubiquinone biosynthesis in Escherichia coli K-12:4-hydroxybenzoate octaprenyltransferase.
The function of ubiquinone in Escherichia coli.
Ubisemiquinone in membranes from Escherichia coli.
Induction of a primary antihapten response in vivo by a graft-vs.-host reaction.
Natural abundance carbon-13 nuclear magnetic resonance spectra of the canine sciatic nerve.
Hapten-specific tolerance: unresponsiveness in the T cell-depleted population.
Natural abundance carbon-13 nuclear magnetic resonance spectra of human serum lipoproteins.
Hapten-specific tolerance in mice. I. Induction with hapten-coupled syngeneic erythrocytes.
Rapid flip-flop of oleic acid across the plasma membrane of adipocytes.
The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.
Free fatty acids modulate intermembrane trafficking of cholesterol by increasing lipid mobilities: novel 13C NMR analyses of free cholesterol partitioning.
Fast flip-flop of cholesterol and fatty acids in membranes: implications for membrane transport proteins.
NMR assignment and structural characterization of the fatty acid binding protein from the flight muscle of Locusta migratoria.
Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T) that is associated with altered lipid metabolism.
Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats.
Sulfonylureas rapidly cross phospholipid bilayer membranes by a free-diffusion mechanism.
Energy translocation across cell membranes and membrane models.
Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation.
MRI of atherothrombosis associated with plaque rupture.
Angiotensin receptor blockade with candesartan attenuates atherosclerosis, plaque disruption, and macrophage accumulation within the plaque in a rabbit model.
Fatty acid interactions with proteins: what X-ray crystal and NMR solution structures tell us.
In vivo molecular imaging of acute and subacute thrombosis using a fibrin-binding magnetic resonance imaging contrast agent.
Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS.
Fatty acid transport and metabolism in HepG2 cells.
Regulation of Toll-like receptor (TLR)2 and TLR4 on CD14dimCD16+ monocytes in response to sepsis-related antigens.
Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes.
Oleate-induced formation of fat cells with impaired insulin sensitivity.
Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy.
Retinaldehyde represses adipogenesis and diet-induced obesity.
Targeted binding of PLA microparticles with lipid-PEG-tethered ligands.
Identification of atherosclerotic lipid deposits by diffusion-weighted imaging.
Brain uptake and utilization of fatty acids, lipids and lipoproteins: application to neurological disorders.
Roundtable discussion of session 1: mechanisms of lipid uptake and transport in the brain.
A model for fatty acid transport into the brain.
Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.
Roundtable discussion of session 4: fatty acids and lipids in brain disorders.
Roundtable discussion of session 3: eicosanoids in brain function.
Roundtable discussion of session 2: lipoproteins and polyunsaturated fatty acids.
Role of caveolin-1 and cholesterol in transmembrane fatty acid movement.
Interactions between fatty acids and alpha-synuclein.
Fatty-acid-binding protein from the flight muscle of Locusta migratoria: evolutionary variations in fatty acid binding.
Location of high and low affinity fatty acid binding sites on human serum albumin revealed by NMR drug-competition analysis.
How fatty acids of different chain length enter and leave cells by free diffusion.
Ex vivo identification of atherosclerotic plaque calcification by a 31P solid-state magnetic resonance imaging technique.
Fluorescence assays for measuring fatty acid binding and transport through membranes.
Acrylodan-labeled intestinal fatty acid-binding protein to measure concentrations of unbound fatty acids.
Relationship of obesity with osteoporosis.
Crystal structure of CETP: new hopes for raising HDL to decrease risk of cardiovascular disease?