Cheng-Chang Lien received his MD from China Medical University in 1997 and earned his PhD in 2003 (under Peter Jonas) with the grade “summa cum laude” at University of Freiburg, Germany. It was in Jonas lab where he studied the correlation between intrinsic properties of hippocampal neurons and gene expression profiles using state-of-the-art patch clamp technique and single cell RT-PCR. He completed his postdoctoral training with Mu-Ming Poo at UC Berkeley, USA in 2006. During this time, he used in vivo whole-cell patch-clamp recording to study how visual experiences modify synaptic connections of the developing visual circuitry.
He became a Principal Investigator and also a faculty member of the Institute of Neuroscience at National Yang-Ming University in 2006. He became Professor since 2015 and has been named as an Alexander von Humboldt fellow. His research focuses on circuit neuroscience and his long-term objective is to correlate information processing in the brain circuits with various behaviors.