Tobias Rose leads the project group ‘Structural and Functional Plasticity of Individual Synapses’ in the department ‘Synapses – Circuits – Plasticity’ at the Max Planck Institute of Neurobiology in Martinsried, Germany. He is also a principal investigator in the collaborative research center ‘Assembly and Function of Neuronal Circuits’. For his PhD (2003-2006) he studied the biophysics of regulated exocytosis of endocrine cells at the European Neuroscience Institute, Göttingen. As a postdoc he then worked together with Thomas Oertner at the Friedrich Miescher Institute in Basel, Switzerland, where he explored the developmental aspects of synaptic vesicle turnover in intact tissue using newly designed tools. In 2010 he joined the department of Tobias Bonhoeffer. Together with three graduate students in his project group he develops new optophysiological chronic imaging approaches to study network stability and the relevance of structural synaptic rearrangements during experience-dependent plasticity both in vivo and in vitro.