New Trends in Biomedical Aging Research
Zinc-Binding Proteins and Immunosenescence: Implications as Biological and Genetic Markers
Zinc–gene interaction related to inflammatory/immune response in ageing
Possible New Antiaging Strategies Related to Neuroendocrine-Immune Interactions
ZINC STATUS, METALLOTHIONEINS AND ATHEROSCLEROSIS IN THE ELDERLY
Zinc and Other Micronutrients for Healthy Aging
Role of Zinc and Selenium in Oxidative Stress and Immunosenescence: Implications for Healthy Ageing and Longevity
L-arginine Reduces Mercury Accumulation in Thymus of Mercury-exposed Mice: Role of Nitric Oxide Synthase Activity and Metallothioneins
A genetic variant near the equine interleukin 6 gene associated with copper:zinc ratio
Effects of human Toll-like receptor 1 polymorphisms on ageing
Zinc, metallothioneins and immunosenescence: effect of zinc supply as nutrigenomic approach
Health status, blood and anthropometrical indices from Greek old and nonagenarian subjects
Diet (zinc)–gene interaction related to inflammatory/immune response in ageing: possible link with frailty syndrome?
Inflammation, genes and zinc in ageing and age-related diseases
Peripheral Mononuclear Cell Rejuvenation for Senescence Surveillance in Alzheimer Disease
Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals.
Endogenous retroelements in cellular senescence and related pathogenic processes: promising drug targets in age-related diseases.
Effect of 6-month caloric restriction on Cu bound to ceruloplasmin in adult overweight subjects.
Serum copper to zinc ratio: Relationship with aging and health status.
Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation.
Effects of zinc-fortified drinking skim milk (as functional food) on cytokine release and thymic hormone activity in very old persons: a pilot study.
Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds.
Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review.
Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review.
Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population.
Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?
Metallothioneins, ageing and cellular senescence: a future therapeutic target.
Peripheral mononuclear cell rejuvenation for senescence surveillance in Alzheimer disease.
Survival study of metallothionein-1 transgenic mice and respective controls (C57BL/6J): influence of a zinc-enriched environment.
Micronutrient (Zn, Cu, Fe)-gene interactions in ageing and inflammatory age-related diseases: implications for treatments.
Zinc: dietary intake and impact of supplementation on immune function in elderly.
Comparison of intracellular zinc signals in nonadherent lymphocytes from young-adult and elderly donors: role of zinc transporters (Zip family) and proinflammatory cytokines.
Speciation of trace elements in human serum by micro anion exchange chromatography coupled with inductively coupled plasma mass spectrometry.
Cu to Zn ratio, physical function, disability, and mortality risk in older elderly (ilSIRENTE study).
BMI, life-style and psychological conditions in a sample of elderly Italian men and women.
Zinc, metallothioneins and immunosenescence.
Noninvasive neonatal thymus graft into the axillary cavity extends the lifespan of old mice.
In vivo effect of alpha-bisabolol, a nontoxic sesquiterpene alcohol, on the induction of spontaneous mammary tumors in HER-2/neu transgenic mice.
Association of MT1A haplotype with cardiovascular disease and antioxidant enzyme defense in elderly Greek population: comparison with an Italian cohort.
Plasma copper/zinc ratio: an inflammatory/nutritional biomarker as predictor of all-cause mortality in elderly population.
l-Arginine normalizes NOS activity and zinc-MT homeostasis in the kidney of mice chronically exposed to inorganic mercury.
Assessment of gene-nutrient interactions on inflammatory status of the elderly with the use of a zinc diet score--ZINCAGE study.
Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects.
NK and NKT cells in aging and longevity: role of zinc and metallothioneins.
Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants.
Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes.
Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects.
A novel Zip2 Gln/Arg/Leu codon 2 polymorphism is associated with carotid artery disease in aging.
Modulation of genes involved in zinc homeostasis in old low-grade atherosclerotic patients under effects of HMG-CoA reductase inhibitors.
Zinc in elderly people: effects of zinc supplementation on psychological dimensions in dependence of IL-6 -174 polymorphism: a Zincage study.
Metallothionein downregulation in very old age: a phenomenon associated with cellular senescence?
Effects of interleukin-6 -174C/G and metallothionein 1A +647A/C single-nucleotide polymorphisms on zinc-regulated gene expression in ageing.
Zinc supplementation in the elderly reduces spontaneous inflammatory cytokine release and restores T cell functions.
+647 A/C and +1245 MT1A polymorphisms in the susceptibility of diabetes mellitus and cardiovascular complications.
Zinc supplementation boosts the stress response in the elderly: Hsp70 status is linked to zinc availability in peripheral lymphocytes.
Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study.
Mediterranean diet and plasma concentration of inflammatory markers in old and very old subjects in the ZINCAGE population study.
Zinc, metallothioneins and longevity: interrelationships with niacin and selenium.
In vitro and in vivo effects of zinc on cytokine signalling in human T cells.
Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles.
Inflammation, genes and zinc in Alzheimer's disease.
Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals.
TH1 and TH2 cell polarization increases with aging and is modulated by zinc supplementation.
Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.
Effects of zinc supplementation on antioxidant enzyme activities in healthy old subjects.
Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes.
Effect of zinc on cellular poly(ADP-ribosyl)ation capacity.
Zinc-bound metallothioneins and immune plasticity: lessons from very old mice and humans.
Zinc dyshomeostasis, ageing and neurodegeneration: implications of A2M and inflammatory gene polymorphisms.
Chronobiology and effects of the age on the immune function: nutritional and genetic background.
[Mercury toxicity: trace element interactions and detoxification activity by L-arginine]
The +838 C/G MT2A polymorphism, metals, and the inflammatory/immune response in carotid artery stenosis in elderly people.
Zinc and inflammatory/immune response in aging.
Psychosocial and biochemical interactions in aging: preliminary results from an Italian old sample of "Zincage" project.
CD14 C (-260)T polymorphism, atherosclerosis, elderly: role of cytokines and metallothioneins.
Zinc-binding proteins (metallothionein and alpha-2 macroglobulin) and immunosenescence.
Polymorphisms in MT1a gene coding region are associated with longevity in Italian Central female population.
Antioxidant enzyme activities in healthy old subjects: influence of age, gender and zinc status: results from the Zincage Project.
Single and three-color flow cytometry assay for intracellular zinc ion availability in human lymphocytes with Zinpyr-1 and double immunofluorescence: relationship with metallothioneins.
Simultaneous evaluation of circulating chemokine and cytokine profiles in elderly subjects by multiplex technology: relationship with zinc status.
Effect of improved zinc status on T helper cell activation and TH1/TH2 ratio in healthy elderly individuals.
Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients.
Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.
Zinc, oxidative stress, genetic background and immunosenescence: implications for healthy ageing.
Synaptic and mitochondrial physiopathologic changes in the aging nervous system and the role of zinc ion homeostasis.
Nutrient-gene interaction in ageing and successful ageing. A single nutrient (zinc) and some target genes related to inflammatory/immune response.
Age and immunity.
Psychosocial aspects and zinc status: is there a relationship with successful aging?
Zinc homeostasis in aging: two elusive faces of the same "metal".
Novel -209A/G MT2A polymorphism in old patients with type 2 diabetes and atherosclerosis: relationship with inflammation (IL-6) and zinc.
Zinc dyshomeostasis: a key modulator of neuronal injury.
1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.
Brain, aging and neurodegeneration: role of zinc ion availability.
The -308G/A polymorphism of TNF-alpha influences immunological parameters in old subjects affected by infectious diseases.
Interrelationship among neutrophil efficiency, inflammation, antioxidant activity and zinc pool in very old age.
Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?
Characterization of the hsp70 response in lymphoblasts from aged and centenarian subjects and differential effects of in vitro zinc supplementation.
Normal phase liquid chromatography-electrospray ionization tandem mass spectrometry analysis of phospholipid molecular species in blood mononuclear cells: application to cystic fibrosis.
NK and NKT cell functions in immunosenescence.
Zinc, immune plasticity, aging, and successful aging: role of metallothionein.
The variations during the circadian cycle of liver CD1d-unrestricted NK1.1+TCR gamma/delta+ cells lead to successful ageing. Role of metallothionein/IL-6/gp130/PARP-1 interplay in very old mice.
Metallothionein isoforms (I+II and III) and interleukin-6 in the hippocampus of old rats: may their concomitant increments lead to neurodegeneration?
High-performance liquid chromatography/electrospray ionization ion-trap tandem mass spectrometric analysis and quantification of phosphatidylcholine molecular species in the serum of cystic fibrosis subjects supplemented with docosahexaenoic acid.
Fatty acids composition of plasma phospholipids and triglycerides in children with cystic fibrosis. The effect of dietary supplementation with an olive and soybean oils mixture.
Use of mathematical models of survivorship in the study of biomarkers of aging: the role of heterogeneity.
Reversed Stereochemical Control in the Presence of CeCl(3) and TiCl(4) in the Lewis Acid Mediated Reduction of alpha-Alkyl-beta-keto Esters by Metal Hydrides. A General Methodology for the Diastereoselective Synthesis of syn- and anti-alpha-Alkyl-beta-hydroxy Esters.
Circadian rhythms of body temperature and locomotor activity in aging BALB/c mice: early and late life span predictors.
Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.
Metallothioneins, longevity and cancer: Comment on "Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain".
Cellular Senescence and Inflammatory Burden as Determinants of Mortality in Elderly People Until the Extreme old age.
Metallothioneins, longevity and cancer: Comment on “Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain”