Ashutosh Mangalam



I completed my PhD from Sanjay Gandhi Postgraduate Institute of Medical Science, Lucknow, India in 2002 and postdoctoral studies from Mayo Clinic. I am currently a faculty in department of Pathology at Carver College of Medicine, University of Iowa, Iowa City, IA. I have authored more than 20 peer reviewed papers in reputed journals, 5 book chapters; one patent, serve as expert reviewer for reputed journals and various grant study sections. My research program focuses on understanding role of gut microbiome in human health and disease as well as to find a better cure for human autoimmune disease multiple sclerosis (MS). To achieve these goals my program has three components: basic research (to understand the disease promoting and protective role of gut microbiome and HLA in inflammatory conditions utilizing novel HLA class-II transgenic mice as model of MS), clinical research (authenticate findings from lab research into MS patients) and translational research (test novel therapies in a preclinical model of MS). My research utilizes novel tools such as HLA class II transgenic mice expressing autoimmune susceptible and resistant genes, and human gut microbiome and metabolome analysis techniques.

Record last modified Oct 2, 2018 1:34:20 PM