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Works (5)

Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity

Nature Communications
2024-02-19 | Journal article
Contributors: María Ángeles Márquez-Moñino; Raquel Ortega-García; Hayley Whitfield; Andrew M. Riley; Lourdes Infantes; Shane W. Garrett; Megan L. Shipton; Charles A. Brearley; Barry V. L. Potter; Beatriz González
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Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1)

Biochemistry
2024-01-02 | Journal article
Contributors: Hayley L. Whitfield; Raquel Faba Rodriguez; Megan L. Shipton; Arthur W.H. Li; Andrew M. Riley; Barry V.L. Potter; Andrew M. Hemmings; Charles A. Brearley
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Expedient synthesis and luminescence sensing of the inositol pyrophosphate cellular messenger 5-PP-InsP5

Chemical Science
2023 | Journal article
Contributors: Megan L. Shipton; Fathima A. Jamion; Simon Wheeler; Andrew M. Riley; Felix Plasser; Barry V. L. Potter; Stephen J. Butler
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Multiple substrate recognition by yeast diadenosine and diphosphoinositol polyphosphate phosphohydrolase through phosphate clamping

Science Advances
2021-04-23 | Journal article
Contributors: María Ángeles Márquez-Moñino; Raquel Ortega-García; Megan L. Shipton; Elsa Franco-Echevarría; Andrew M. Riley; Julia Sanz-Aparicio; Barry V. L. Potter; Beatriz González
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Both d- and l-Glucose Polyphosphates Mimic d-myo-Inositol 1,4,5-Trisphosphate: New Synthetic Agonists and Partial Agonists at the Ins(1,4,5)P3 Receptor

Journal of Medicinal Chemistry
2020-05-28 | Journal article
Contributors: Megan L. Shipton; Andrew M. Riley; Ana M. Rossi; Charles A. Brearley; Colin W. Taylor; Barry V. L. Potter
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