Personal information

Activities

Employment (2)

Iran University of Medical Sciences: Tehran, IR

2021-11-28 to present | Professor (Hematology and Blood Banking)
Employment
Source: Self-asserted source
Majid Safa

Iran University of Medical Sciences: Tehran, IR

2012-02-04 to 2021-11-27 | Associate Professor (Laboratory Hematology and Blood Banking)
Employment
Source: Self-asserted source
Majid Safa

Education and qualifications (4)

Tehran University of Medical Sciences: Tehran, Tehran, IR

2006-12-20 to 2011-02-15 | Ph.D. Laboratory Hematology and Blood banking (Laboratory Hematology and Blood banking)
Education
Source: Self-asserted source
Majid Safa

Tarbiat Modares University Faculty of Medical Sciences: Tehran, Tehran, IR

2004-09-20 to 2006-12-20 | M.Sc. Laboratory Hematology and Blood banking (Laboratory Hematology and Blood banking)
Education
Source: Self-asserted source
Majid Safa

Isfahan University of Medical Sciences: Isfahan, Isfahan, IR

2001-09-20 to 2003-08-20 | B.Sc. Medical Laboratory Sciences (Medical Laboratory Sciences)
Education
Source: Self-asserted source
Majid Safa

Shiraz University of Medical Sciences: Shiraz, IR

1999-09-20 to 2001-08-20 | A.D. Medical Laboratory Sciences (Medical Laboratory Sciences)
Education
Source: Self-asserted source
Majid Safa

Works (46)

Design and fabrication of novel microfluidic-based droplets for drug screening on a chronic myeloid leukemia cell line

PLOS ONE
2025-01-15 | Journal article
Contributors: Niloofar Jaafari; Jian Wu; Amir Asri Kojabad; Rima Manafi Shabestari; Majid Safa
Source: check_circle
Crossref

CDC27 gene expression patterns as a potential biomarker in Acute Leukemia

Molecular Biology Reports
2024-12 | Journal article
Contributors: Yasaman Pouriafar; Shahrbano Rostami; Nasrin Alizadghandforoush; Mahmood Barati; Ali Amini; Majid Safa
Source: check_circle
Crossref

Drivers of consumers’ behavioral intention toward private umbilical cord blood banking: a review

Cell and Tissue Banking
2023-09 | Journal article
Contributors: Neda Saraygord-Afshari; Sonia Ghayem; Reza Foudazi; Majid Safa
Source: check_circle
Crossref

Ultrasensitive quantitation of FLT3-ITD mutation in patients with acute myeloid leukemia using ddPCR

Molecular Biology Reports
2023-07 | Journal article
Contributors: Amir Asri kojabad; Rouzbeh Chegeni; Shaharbano Rostami; Farhad Zaker; Majid Safa
Source: check_circle
Crossref

Viral vectors and extracellular vesicles: innate delivery systems utilized in CRISPR/Cas-mediated cancer therapy

Cancer Gene Therapy
2023-07 | Journal article
Contributors: Seyed Esmaeil Ahmadi; Maral Soleymani; Fahimeh Shahriyary; Mohammad Reza Amirzargar; Mahya Ofoghi; Mohammad Davood Fattahi; Majid Safa
Source: check_circle
Crossref

A straightforward microfluidic-based approach toward optimizing transduction efficiency of HIV-1-derived lentiviral vectors in BCP-ALL cells

Biotechnology Reports
2023-06 | Journal article
Contributors: Seyed Esmaeil Ahmadi; Rima Manafi Shabestari; Amir Asri kojabad; Majid Safa
Source: check_circle
Crossref

Reference interval of antithrombin, protein C, and protein S activities in healthy adults in Iran, the effect of age, sex, oral contraceptive intake, and menopause

International Journal of Laboratory Hematology
2022-06 | Journal article
Contributors: Shadi Tabibian; Majid Khoshmirsafa; Mostafa Paridar; Abbas Motevalian; Mahdi Shekarabi; Majid Safa
Source: check_circle
Crossref

Correction to: MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies

Journal of Hematology & Oncology
2021-12 | Journal article
Contributors: Seyed Esmaeil Ahmadi; Samira Rahimi; Bahman Zarandi; Rouzbeh Chegeni; Majid Safa
Source: check_circle
Crossref

Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment

Experimental Hematology & Oncology
2021-11-03 | Journal article
Contributors: Mohsen Valikhani; Elahe Rahimian; Seyed Esmaeil Ahmadi; Rouzbeh Chegeni; Majid Safa
Source: check_circle
Crossref

MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies

Journal of Hematology & Oncology
2021-08-09 | Journal article
Contributors: Seyed Esmaeil Ahmadi; Samira Rahimi; Bahman Zarandi; Rouzbeh Chegeni; Majid Safa
Source: check_circle
Crossref

DNA repair pathways as guardians of the genome: Therapeutic potential and possible prognostic role in hematologic neoplasms

DNA Repair
2020-12 | Journal article
Contributors: Elahe Rahimian; Ali Amini; Fatemeh Alikarami; Seyed Mohammad Sadegh Pezeshki; Najmaldin Saki; Majid Safa
Source: check_circle
Crossref

Suppression of c-Myc using 10058-F4 exerts caspase-3-dependent apoptosis and intensifies the antileukemic effect of vincristine in pre-B acute lymphoblastic leukemia cells.

Journal of cellular biochemistry
2019-04-07 | Journal article
Source: Self-asserted source
Majid Safa

Antileukemic effects of neurokinin-1 receptor inhibition on hematologic malignant cells: A novel therapeutic potential for aprepitant

Anti-Cancer Drugs
2018 | Journal article
EID:

2-s2.0-85042697199

Contributors: Bayati, S.; Razani, E.; Bashash, D.; Safaroghli-Azar, A.; Safa, M.; Ghaffari, S.H.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress

Life Sciences
2018 | Journal article
EID:

2-s2.0-85036495883

Contributors: Dehdashtian, E.; Mehrzadi, S.; Yousefi, B.; Hosseinzadeh, A.; Reiter, R.J.; Safa, M.; Ghaznavi, H.; Naseripour, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Molecular diagnosis of factor XIII deficiency, data from comprehensive coagulation laboratory in Iran

Blood Coagulation and Fibrinolysis
2018 | Journal article
EID:

2-s2.0-85041454059

Contributors: Gheidishahran, M.; Dorgalaleh, A.; Tabibian, S.; Shams, M.; Moghaddam, E.S.; Khosravi, S.; Naderi, M.; Kahraze, S.; Lotfi, F.; Kazeme, A. et al.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Overexpression of MiR-138 inhibits cell growth and induces caspase-mediated apoptosis in acute promyelocytic leukemia cell line

International Journal of Molecular and Cellular Medicine
2018 | Journal article
EID:

2-s2.0-85046367638

Contributors: Shabestari, R.M.; Alikarami, F.; Bashash, D.; Paridar, M.; Safa, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

RITA induces apoptosis in p53-null K562 leukemia cells by inhibiting STAT5, Akt, and NF-κB signaling pathways.

Anti-cancer drugs
2018-10-01 | Journal article
Source: Self-asserted source
Majid Safa

Dual blockade of VEGFR1 and VEGFR2 by a novel peptide abrogates VEGF-driven angiogenesis, tumor growth, and metastasis through PI3K/AKT and MAPK/ERK1/2 pathway.

Biochimica et biophysica acta. General subjects
2018-08-21 | Journal article
Source: Self-asserted source
Majid Safa

Anti-tumor activity of PI3K-δ inhibitor in hematologic malignant cells: Shedding new light on resistance to Idelalisib

International Journal of Biochemistry and Cell Biology
2017 | Journal article
EID:

2-s2.0-85013913759

Contributors: Bashash, D.; Safaroghli-Azar, A.; Dadashi, M.; Safa, M.; Momeny, M.; Ghaffari, S.H.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Cabazitaxel inhibits proliferation and potentiates the radiation response of U87MG glioblastoma cells

Cell Biology International
2017 | Journal article
EID:

2-s2.0-85042044602

Contributors: Neshasteh-Riz, A.; Zeinizade, E.; Safa, M.; Mousavizadeh, K.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

CREB knockdown inhibits growth and induces apoptosis in human pre-B acute lymphoblastic leukemia cells through inhibition of prosurvival signals

Biomedicine and Pharmacotherapy
2017 | Journal article
EID:

2-s2.0-85008240192

Contributors: Shabestari, R.M.; Safa, M.; Alikarami, F.; Banan, M.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Indole-3-carbinol induces apoptosis of chronic myelogenous leukemia cells through suppression of STAT5 and Akt signaling pathways

Tumor Biology
2017 | Journal article
EID:

2-s2.0-85025076289

Contributors: Safa, M.; Jafari, L.; Alikarami, F.; Shabestari, R.M.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Inhibition of DNA-PK enhances chemosensitivity of B-cell precursor acute lymphoblastic leukemia cells to doxorubicin

Biomedicine and Pharmacotherapy
2017 | Journal article
EID:

2-s2.0-85027878095

Contributors: Alikarami, F.; Safa, M.; Faranoush, M.; Hayat, P.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Minimal factor XIII activity level to prevent major spontaneous bleeds: comment

Journal of Thrombosis and Haemostasis
2017 | Journal article
EID:

2-s2.0-85032813651

Contributors: Dorgalaleh, A.; Tabibian, S.H.; Safa, M.; Shams, M.; Naderi, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Novel pan PI3K inhibitor-induced apoptosis in APL cells correlates with suppression of telomerase: An emerging mechanism of action of BKM120

International Journal of Biochemistry and Cell Biology
2017 | Journal article
EID:

2-s2.0-85027959162

Contributors: Bashash, D.; Delshad, M.; Safaroghli-Azar, A.; Safa, M.; Momeny, M.; Ghaffari, S.H.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

PRIMA-1 induces caspase-mediated apoptosis in acute promyelocytic leukemia NB4 cells by inhibition of nuclear factor-κB and downregulation of Bcl-2, XIAP, and c-Myc

Anti-Cancer Drugs
2017 | Journal article
EID:

2-s2.0-84983514838

Contributors: Farhadi, E.; Safa, M.; Sharifi, A.M.; Bashash, D.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Protective mechanisms of melatonin against hydrogenperoxide- induced toxicity in human bone-marrow-derived mesenchymal stem cells

Canadian Journal of Physiology and Pharmacology
2017 | Journal article
EID:

2-s2.0-85021832493

Contributors: Mehrzadi, S.; Safa, M.; Kamrava, S.K.; Darabi, R.; Hayat, P.; Motevalian, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Cellular activity of Wharton's Jelly-derived mesenchymal stem cells on electrospun fibrous and solvent-cast film scaffolds

Journal of Biomedical Materials Research - Part A
2016 | Journal article
EID:

2-s2.0-84983095483

Contributors: Bagher, Z.; Ebrahimi-Barough, S.; Azami, M.; Safa, M.; Joghataei, M.T.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Cyclic AMP-induced p53 destabilization is independent of CREB in pre-B acute lymphoblastic leukemia cells

International Journal of Molecular and Cellular Medicine
2016 | Journal article
EID:

2-s2.0-85021950562

Contributors: Shabestari, R.M.; Safa, M.; Banan, M.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

miR-101 sensitizes K562 cell line to imatinib through Jak2 downregulation and inhibition of NF-κB target genes

Tumor Biology
2016 | Journal article
EID:

2-s2.0-84982182000

Contributors: Farhadi, E.; Zaker, F.; Safa, M.; Rezvani, M.R.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Rapid induction of neural differentiation in human umbilical cord matrix mesenchymal stem cells by cAMP-elevating agents

International Journal of Molecular and Cellular Medicine
2016 | Journal article
EID:

2-s2.0-85018283806

Contributors: Shahbazi, A.; Safa, M.; Alikarami, F.; Kargozar, S.; Asadi, M.H.; Joghataei, M.T.; Soleimani, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Indole-3-carbinol suppresses NF-κB activity and stimulates the p53 pathway in pre-B acute lymphoblastic leukemia cells

Tumor Biology
2015 | Journal article
EID:

2-s2.0-84929957841

Contributors: Safa, M.; Tavasoli, B.; Manafi, R.; Kiani, F.; Kashiri, M.; Ebrahimi, S.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Induction of p53-dependent apoptosis in pre-B acute lymphoblastic leukemia cell line (NALM-6) by small molecule RITA

Journal of Zanjan University of Medical Sciences and Health Services
2015 | Journal article
EID:

2-s2.0-84937928362

Contributors: Kiani Nodeh, F.; Manafi Shabestari, R.; Kazemi, A.; Safa, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-κB pathway

Tumor Biology
2015 | Journal article
EID:

2-s2.0-84949110713

Contributors: Fatemi, A.; Safa, M.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells

Archives of Biochemistry and Biophysics
2015 | Journal article
EID:

2-s2.0-84920038043

Contributors: Ghorbani, A.; Jeddi-Tehrani, M.; Saidpour, A.; Safa, M.; Bayat, A.A.; Zand, H.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Synergistic Apoptotic Effect of Crocin and Paclitaxel or Crocin and Radiation on MCF-7 Cells, a Type of Breast Cancer Cell Line

International Journal of Breast Cancer
2015 | Journal article
EID:

2-s2.0-84961755631

Contributors: Vali, F.; Changizi, V.; Safa, M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

CAMP protects acute promyelocytic leukemia cells from arsenic trioxide-induced caspase-3 activation and apoptosis

European Journal of Pharmacology
2014 | Journal article
EID:

2-s2.0-84901102316

Contributors: Safa, M.; Mousavizadeh, K.; Noori, S.; Pourfathollah, A.; Zand, H.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Investigating the Protective Effect of Lithium Against High Glucose-Induced Neurotoxicity in PC12 Cells: Involvements of ROS, JNK and P38 MAPKs, and Apoptotic Mitochondria Pathway

Cellular and Molecular Neurobiology
2014 | Journal article
EID:

2-s2.0-84912019376

Contributors: Aminzadeh, A.; Dehpour, A.R.; Safa, M.; Mirzamohammadi, S.; Sharifi, A.M.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

The effect of elevated cAMP levels on phosphorylation of Bcl-2-Associated death promoter protein in Pre-B acute lymphoblastic leukemia cell line (NALM-6) treated with doxorubicin

Journal of Zanjan University of Medical Sciences and Health Services
2014 | Journal article
EID:

2-s2.0-84911493681

Contributors: Kashiri, M.; Safa, M.; Kazemi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Cyclic AMP-induced p53 destabilization is independent of EPAC in pre-B acute lymphoblastic leukemia cells in vitro

Journal of Receptors and Signal Transduction
2011 | Journal article
EID:

2-s2.0-79957802896

Contributors: Safa, M.; Kazemi, A.; Zaker, F.; Razmkhah, F.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

RITA enhances chemosensivity of pre-B ALL cells to doxorubicin by inducing p53- dependent apoptosis

Hematology
2011 | Journal article
EID:

2-s2.0-79960130289

Contributors: Kazemi, A.; Safa, M.; Shahbazi, A.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Elevation of cyclic AMP causes an imbalance between NF-κB and p53 in NALM-6 cells treated by doxorubicin

FEBS Letters
2010 | Journal article
EID:

2-s2.0-77955277457

Contributors: Safa, M.; Zand, H.; Mousavizadeh, K.; Kazemi, A.; Bakhshayesh, M.; Hayat, P.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Inhibitory role of cAMP on doxorubicin-induced apoptosis in pre-B ALL cells through dephosphorylation of p53 serine residues

Apoptosis
2010 | Journal article
EID:

2-s2.0-77949265520

Contributors: Safa, M.; Kazemi, A.; Zand, H.; Azarkeivan, A.; Zaker, F.; Hayat, P.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

Detection of four β-thalassemia point mutations in Iranians using a PCR-ELISA genotyping system

Molecular and Cellular Probes
2008 | Journal article
EID:

2-s2.0-40149103110

Contributors: Gill, P.; Forouzandeh, M.; Eshraghi, N.; Ghalami, M.; Safa, M.; Noori-Daloii, M.-R.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

High resolution allotyping of four alleles of HLA-DRB1*01 group in Iranians using reverse-SSOPH assay in comparison with DNA sequencing and PCR-SSP

Journal of Biological Sciences
2008 | Journal article
EID:

2-s2.0-52349088855

Contributors: Safa, M.; Forouzandeh, M.; Pourfathollah, A.; Gill, P.; Rasaee, M.J.; Yari, F.; Shahbazi, A.; Soltanpour, M.S.; Mayor, N.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier

The association between common C677T mutation in methylenetetrahydrofolate reductase gene and the risk of venous thrombosis in an Iranian population

Laboratory Medicine
2008 | Journal article
EID:

2-s2.0-62749191484

Contributors: Soltanpour, M.S.; Soheili, Z.; Pourfathollah, A.A.; Samiei, S.; Meshkani, R.; Deyhim, M.R.; Safa, M.; Ataei, Z.
Source: Self-asserted source
Majid Safa via Scopus - Elsevier