Analysing variation in Drosophila aging across independent experimental studies: a meta-analysis of survival data.
Unlocking the potential of survival data for model organisms through a new database and online analysis platform: SurvCurv.
Transcriptional feedback in the insulin signalling pathway modulates ageing in both Caenorhabditis elegans and Drosophila melanogaster.
Elucidating human phosphatase-substrate networks.
Abstracting knowledge from the protein data bank.
The EBI enzyme portal.
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures.
Current challenges in genome annotation through structural biology and bioinformatics.
ELIXIR: a distributed infrastructure for European biological data.
FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.
Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.
Women in science.
Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide II.
Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing.
Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio-computational analysis.
Minimum information about a bioactive entity (MIABE).
The metastasis-promoting phosphatase PRL-3 shows activity toward phosphoinositides.
The new science of ageing.
Computational biology for ageing.
Extending CATH: increasing coverage of the protein structure universe and linking structure with function.
1,000 structures and more from the MCSG.
Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling.
The structures and physicochemical properties of organic cofactors in biocatalysis.
The CoFactor database: organic cofactors in enzyme catalysis.
Heme proteins--diversity in structural characteristics, function, and folding.
DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO.
On the diversity of physicochemical environments experienced by identical ligands in binding pockets of unrelated proteins.
Electrostatics of aquaporin and aquaglyceroporin channels correlates with their transport selectivity.
Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.
The (non)malignancy of cancerous amino acidic substitutions.
The European Bioinformatics Institute's data resources.
Domain-ligand mapping for enzymes.
PoreLogo: a new tool to analyse, visualize and compare channels in transmembrane proteins.
Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure.
Mapping human metabolic pathways in the small molecule chemical space.
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Prepublication data sharing.
Metal-MACiE: a database of metals involved in biological catalysis.
The fine details of evolution.
Missing in action: enzyme functional annotations in biological databases.
The CATH hierarchy revisited-structural divergence in domain superfamilies and the continuity of fold space.
Understanding the functional roles of amino acid residues in enzyme catalysis.
PoreWalker: a novel tool for the identification and characterization of channels in transmembrane proteins from their three-dimensional structure.
The structural basis of allosteric regulation in proteins.
WSsas: a web service for the annotation of functional residues through structural homologues.
Structural analysis of metal sites in proteins: non-heme iron sites as a case study.
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
Genome and proteome annotation: organization, interpretation and integration.
Protein promiscuity and its implications for biotechnology.
The CATH classification revisited--architectures reviewed and new ways to characterize structural divergence in superfamilies.
Annotations for all by all - the BioSapiens network.
Small Molecule Subgraph Detector (SMSD) toolkit.
Protein function annotation by homology-based inference.
The Protein Feature Ontology: a tool for the unification of protein feature annotations.
Metal ions in biological catalysis: from enzyme databases to general principles.
Detection of 3D atomic similarities and their use in the discrimination of small molecule protein-binding sites.
Evolution of binding sites for zinc and calcium ions playing structural roles.
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.
Understanding the molecular machinery of genetics through 3D structures.
PROCOGNATE: a cognate ligand domain mapping for enzymes.
Activation of the SPS amino acid-sensing pathway in Saccharomyces cerevisiae correlates with the phosphorylation state of a sensor component, Ptr3.
Molecular docking for substrate identification: the short-chain dehydrogenases/reductases.
Metabolic innovations towards the human lineage.
The chemistry of protein catalysis.
Evolution of enzymes and pathways for the biosynthesis of cofactors.
Evolutionary models for formation of network motifs and modularity in the Saccharomyces transcription factor network.
Construction, visualisation, and clustering of transcription networks from microarray expression data.
The geometry of interactions between catalytic residues and their substrates.
Structural and chemical profiling of the human cytosolic sulfotransferases.
Towards fully automated structure-based function prediction in structural genomics: a case study.
Shape variation in protein binding pockets and their ligands.
The implications of alternative splicing in the ENCODE protein complement.
MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms.
The CATH domain structure database: new protocols and classification levels give a more comprehensive resource for exploring evolution.
Analysis of binding site similarity, small-molecule similarity and experimental binding profiles in the human cytosolic sulfotransferase family.
Correcting for sequence biases in present/absent calls.
Estimation and correction of non-specific binding in a large-scale spike-in experiment.
Evolutionary conservation of regulated longevity assurance mechanisms.
Cognate ligand domain mapping for enzymes.
Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472].
Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.
Protein superfamily evolution and the last universal common ancestor (LUCA).
A bioinformatician's view of the metabolome.
An analysis of intron positions in relation to nucleotides, amino acids, and protein secondary structure.
Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans.
Integrating biological data through the genome.
Conformational diversity of ligands bound to proteins.
Introduction. Bioinformatics: from molecules to systems.
A method for localizing ligand binding pockets in protein structures.
Relating tissue specialization to the differentiation of expression of singleton and duplicate mouse proteins.
MACiE: a database of enzyme reaction mechanisms.
Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression.
Understanding nature's catalytic toolkit.
A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1.
Morphological aspects of oligomeric protein structures.
Protein function prediction using local 3D templates.
Effective function annotation through catalytic residue conservation.
ProFunc: a server for predicting protein function from 3D structure.
The complement of enzymatic sets in different species.
Predicting protein function from sequence and structural data.
Prediction of protein function from structure: insights from methods for the detection of local structural similarities.
Progress of structural genomics initiatives: an analysis of solved target structures.
Real spherical harmonic expansion coefficients as 3D shape descriptors for protein binding pocket and ligand comparisons.
Using a library of structural templates to recognise catalytic sites and explore their evolution in homologous families.
A ligand-centric analysis of the diversity and evolution of protein-ligand relationships in E.coli.
Conformational changes observed in enzyme crystal structures upon substrate binding.
The CATH Domain Structure Database and related resources Gene3D and DHS provide comprehensive domain family information for genome analysis.
PDBsum more: new summaries and analyses of the known 3D structures of proteins and nucleic acids.
The European Bioinformatics Institute's data resources: towards systems biology.
Microeconomic principles explain an optimal genome size in bacteria.
Detecting DNA-binding helix-turn-helix structural motifs using sequence and structure information.
Relationship between the tissue-specificity of mouse gene expression and the evolutionary origin and function of the proteins.
Protein families and their evolution-a structural perspective.
Toward the detection and validation of repeats in protein structure.
A practical and robust sequence search strategy for structural genomics target selection.
SCOPEC: a database of protein catalytic domains.
Ligand selectivity and competition between enzymes in silico.
Computational analysis of alpha-helical membrane protein structure: implications for the prediction of 3D structural models.
Conformational change in substrate binding, catalysis and product release: an open and shut case?
Searching for functional sites in protein structures.
Evolution of protein superfamilies and bacterial genome size.
The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data.
Identifying DNA-binding proteins using structural motifs and the electrostatic potential.
A structure-based anatomy of the E.coli metabolome.
Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins.
Molecular basis of inherited diseases: a structural perspective.
An algorithm for constraint-based structural template matching: application to 3D templates with statistical analysis.
Recognizing the fold of a protein structure.
A template search reveals mechanistic similarities and differences in beta-ketoacyl synthases (KAS) and related enzymes.
Catalysing new reactions during evolution: economy of residues and mechanism.
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli.
Using a neural network and spatial clustering to predict the location of active sites in enzymes.
Diversity of protein-protein interactions.
Analysis of metabolic networks using a pathway distance metric through linear programming.
Using structural motif templates to identify proteins with DNA binding function.
Sequences and topology.
A novel approach to the recognition of protein architecture from sequence using Fourier analysis and neural networks.
Gene3D: structural assignments for the biologist and bioinformaticist alike.
Structural characterisation and functional significance of transient protein-protein interactions.
Target selection and determination of function in structural genomics.
From protein structure to biochemical function?
Inferring protein function from structure.
Protein-DNA interactions: the story so far and a new method for prediction.
Quantifying the similarities within fold space.
Analysis of catalytic residues in enzyme active sites.
Sequence and structural differences between enzyme and nonenzyme homologs.
Prediction of strand pairing in antiparallel and parallel beta-sheets using information theory.
Plasticity of enzyme active sites.
Toward predicting protein topology: an approach to identifying beta hairpins.
One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions.
Protein-DNA interactions: amino acid conservation and the effects of mutations on binding specificity.
The CCPN project: an interim report on a data model for the NMR community.
Pathway evolution, structurally speaking.
Homology, pathway distance and chromosomal localization of the small molecule metabolism enzymes in Escherichia coli.
Gene3D: structural assignment for whole genes and genomes using the CATH domain structure database.
RTG-dependent mitochondria-to-nucleus signaling is regulated by MKS1 and is linked to formation of yeast prion [URE3].
Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.
Wavelet transforms for the characterization and detection of repeating motifs.
The CATH protein family database: a resource for structural and functional annotation of genomes.
A Constraint-Based System for Protein Motif-Searching, Pattern Discovery and Structure Comparison
A Constraint--Based System for Protein Motif--Searching, Pattern Discovery and Structure Comparison
Topology-based protein structure comparison using a pattern discovery technique (Extended Abstract)
A computer system to perform structure comparison using TOPS representations of protein structure
A Constraint--Based System for Protein Motif--Searching, Pattern Discovery and Structure Comparison
A Constraint--Based System for Protein Motif--Searching, Pattern Discovery and Structure Comparison
Prediction of protein structure from amino acid sequence.
Prediction of protein structure from amino acid sequence.
On the conformation of proteins: hydrophobic ordering of strands in beta-pleated sheets.
On the conformation of proteins: towards the prediction of strand arrangements in beta-pleated sheets.
On the conformation of proteins: an analysis of beta-pleated sheets.
On the conformation of proteins: the handedness of the connection between parallel beta-strands.
An analysis of the three-dimensional structure of chicken triose phosphate isomerase.
On the conformation of proteins: the handedness of the beta-strand-alpha-helix-beta-strand unit.
Conformational energy calculations for dinucleotide molecules. A systematic study of dinucleotide conformation, with application to diadenosine pyrophosphate.
Conformational energy calculations for dinucleotide molecules. A study of the component mononucleotide adenosine 3'-monophosphate.
Protein Data Resources
Exploring the biological and chemical complexity of the ligases.
EC-BLAST: a tool to automatically search and compare enzyme reactions.
The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes.
LigSearch: a knowledge-based web server to identify likely ligands for a protein target.
Amino acid changes in disease-associated variants differ radically from variants observed in the 1000 genomes project dataset.
The Ramachandran plot and protein structure validation
Enhanced DNA binding capacity on up-regulated epidermal wild-type p53 in vitiligo by H2O2-mediated oxidation: a possible repair mechanism for DNA damage.
Protein Function Prediction from Structure in Structural Genomics and its Contribution to the Study of Health and Disease
New open drug activity data at EBI
SPINE bioinformatics and data-management aspects of high-throughput structural biology.
HTHquery: a method for detecting DNA-binding proteins with a helix-turn-helix structural motif.
Amino acid architecture and the distribution of polar atoms on the surfaces of proteins.
Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1.
An examination of the conservation of surface patch polarity for proteins.
Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population.
The CATH domain structure database.
Small-molecule metabolism: an enzyme mosaic.
The (betaalpha)(8) glycosidases: sequence and structure analyses suggest distant evolutionary relationships.
On the molecular discrimination between adenine and guanine by proteins.
Conservation helps to identify biologically relevant crystal contacts.
The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli.
Amino acid-base interactions: a three-dimensional analysis of protein-DNA interactions at an atomic level.
From genome to function.
Evolution of function in protein superfamilies, from a structural perspective.
Protein-RNA interactions: a structural analysis.
The Hans Neurath Award lecture of The Protein Society: proteins-- a testament to physics, chemistry, and evolution.
Protein-protein interfaces: analysis of amino acid conservation in homodimers.
A rapid classification protocol for the CATH Domain Database to support structural genomics.
From structure to function: approaches and limitations.
Discriminating between homodimeric and monomeric proteins in the crystalline state.
Comparison of functional annotation schemes for genomes.
The CATH Dictionary of Homologous Superfamilies (DHS): a consensus approach for identifying distant structural homologues.
Using the CATH domain database to assign structures and functions to the genome sequences.
Protein domain interfaces: characterization and comparison with oligomeric protein interfaces.
Analysis and prediction of carbohydrate binding sites.
Assigning genomic sequences to CATH.
An overview of the structures of protein-DNA complexes.
Evolution of protein function, from a structural perspective.
Protein folds, functions and evolution.
Barrel structures in proteins: automatic identification and classification including a sequence analysis of TIM barrels.
Polymerase chain reaction (PCR)-based typing analysis of atypical isolates of the fish pathogen Aeromonas salmonicida.
From protein structure to function.
DOMPLOT: a program to generate schematic diagrams of the structural domain organization within proteins, annotated by ligand contacts.
Protein side-chain conformation: a systematic variation of chi 1 mean values with resolution - a consequence of multiple rotameric states?
Prediction of the location and type of beta-turns in proteins using neural networks.
Correlation of observed fold frequency with the occurrence of local structural motifs.
Protein-DNA interactions: A structural analysis.
Factors limiting the performance of prediction-based fold recognition methods.
Protein structural topology: Automated analysis and diagrammatic representation.
Three-dimensional structure analysis of PROSITE patterns.
Small subunit rRNA gene sequences of Aeromonas salmonicida subsp. smithia and Haemophilus piscium reveal pronounced similarities with A. salmonicida subsp. salmonicida.
The CATH Database provides insights into protein structure/function relationships.
Contemporary approaches to protein structure classification.
Classifying a protein in the CATH database of domain structures.
New tools and resources for analysing protein structures and their interactions.
Determinants of strand register in antiparallel beta-sheets of proteins.
Validation of protein models derived from experiment.
Evolution of the androgen receptor: structure-function implications.
Sequences annotated by structure: a tool to facilitate the use of structural information in sequence analysis.
PQS: a protein quaternary structure file server.
1H NMR structure of an antifungal gamma-thionin protein SIalpha1: similarity to scorpion toxins.
Protein structure prediction.
Protein folds and functions.
Dihydrofolate reductase: a potential drug target in trypanosomes and leishmania.
Assessment of conformational parameters as predictors of limited proteolytic sites in native protein structures.
Characterization of atypical Aeromonas salmonicida by different methods.
Small binding proteins selected from a combinatorial repertoire of knottins displayed on phage.
Domain assignment for protein structures using a consensus approach: characterization and analysis.
Structural studies of Impatiens balsamina antimicrobial protein (Ib-AMP1).
An atlas of protein topology cartoons available on the World-Wide Web.
NUCPLOT: a program to generate schematic diagrams of protein-nucleic acid interactions.
PDBsum: a Web-based database of summaries and analyses of all PDB structures.
Non-randomness in side-chain packing: the distribution of interplanar angles.
TESS: a geometric hashing algorithm for deriving 3D coordinate templates for searching structural databases. Application to enzyme active sites.
Analysis of protein-protein interaction sites using surface patches.
Prediction of protein-protein interaction sites using patch analysis.
Modelling protein unfolding: hen egg-white lysozyme.
CATH--a hierarchic classification of protein domain structures.
Structures of N-termini of helices in proteins.
Assessment of comparative modeling in CASP2.
Multiple solution conformations of the integrin-binding cyclic pentapeptide cyclo(-Ser-D-Leu-Asp-Val-Pro-). Analysis of the (phi, psi) space available to cyclic pentapeptides.
Deviations from planarity of the peptide bond in peptides and proteins.
Protein clefts in molecular recognition and function.
AQUA and PROCHECK-NMR: programs for checking the quality of protein structures solved by NMR.
Protein recognition of adenylate: an example of a fuzzy recognition template.
Structural families in loops of homologous proteins: automatic classification, modelling and application to antibodies.
Antibody-antigen interactions: contact analysis and binding site topography.
Analysis of domain structural class using an automated class assignment protocol.
Macromolecular structure information and databases. The EU BRIDGE Database Project Consortium.
Solution structure of a biologically active cyclic LDV peptide analogue containing a type II' beta-turn mimetic.
Derivation of 3D coordinate templates for searching structural databases: application to Ser-His-Asp catalytic triads in the serine proteinases and lipases.
X-SITE: use of empirically derived atomic packing preferences to identify favourable interaction regions in the binding sites of proteins.
Potential energy functions for threading.
Towards meeting the Paracelsus Challenge: The design, synthesis, and characterization of paracelsin-43, an alpha-helical protein with over 50% sequence identity to an all-beta protein.
Molecular recognition by proteins: protein-ligand interactions from a structural perspective.
PROMOTIF--a program to identify and analyze structural motifs in proteins.
Analysis of main chain torsion angles in proteins: prediction of NMR coupling constants for native and random coil conformations.
Protein fold recognition by sequence threading: tools and assessment techniques.
Principles of protein-protein interactions.
Functional and modelling studies of the binding of human monoclonal anti-DNA antibodies to DNA.
Successful protein fold recognition by optimal sequence threading validated by rigorous blind testing.
Long loops in proteins.
Structural similarity between the pleckstrin homology domain and verotoxin: the problem of measuring and evaluating structural similarity.
Intrinsic phi, psi propensities of amino acids, derived from the coil regions of known structures.
Protein folds: towards understanding folding from inspection of native structures.
LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions.
Protein-protein interactions: a review of protein dimer structures.
Protein superfamilies and domain superfolds.
A revised set of potentials for beta-turn formation in proteins.
Amino/aromatic interactions in proteins: is the evidence stacked against hydrogen bonding?
NMR and crystallography--complementary approaches to structure determination.
Satisfying hydrogen bonding potential in proteins.
Modeling studies of the change in conformation required for cleavage of limited proteolytic sites.
A model recognition approach to the prediction of all-helical membrane protein structure and topology.
An algorithm for automatically generating protein topology cartoons.
The BC loop in poliovirus coat protein VP1: an ideal acceptor site for major insertions.
Conformational analysis of protein structures derived from NMR data.
Comparison of conformational characteristics in structurally similar protein pairs.
Alpha plus beta folds revisited: some favoured motifs.
Identification, classification, and analysis of beta-bulges in proteins.
A study of structural determinants in the interleukin-1 fold.
Peptide-protein interactions: an overview.
Topological and stereochemical restrictions in beta-sandwich protein structures.
Identification and classification of protein fold families.
Main-chain bond lengths and bond angles in protein structures.
PROCHECK: a program to check the stereochemical quality of protein structures.
Atomic environments of arginine side chains in proteins.
The Greek key motif: extraction, classification and analysis.
Recurrence of a binding motif?
Molecular modelling and epitope prediction of gp29 from lymphatic filariae.
A study into the effects of protein binding on nucleotide conformation.
Recurring structural motifs in proteins with different functions.
Accommodating sequence changes in beta-hairpins in proteins.
Towards an understanding of the arginine-aspartate interaction.
A new approach to protein fold recognition.
The rapid generation of mutation data matrices from protein sequences.
Stereochemical quality of protein structure coordinates.
Substrate recognition by proteinases.
A topological model for hepatitis B surface antigen.
Protein structure. Prediction of progress at last.
Analysis of protein main-chain solvation as a function of secondary structure.
Structure prediction and modelling.
Molecular recognition. Conformational analysis of limited proteolytic sites and serine proteinase protein inhibitors.
Pi-pi interactions: the geometry and energetics of phenylalanine-phenylalanine interactions in proteins.
Influence of proline residues on protein conformation.
A novel method for the modelling of peptide ligands to their receptors.
Conformation of beta hairpins in protein structures: classification and diversity in homologous structures.
Influence of secondary structure on the hydration of serine, threonine and tyrosine residues in proteins.
Beta-turns and their distortions: a proposed new nomenclature.
SIRIUS. An automated method for the analysis of the preferred packing arrangements between protein groups.
HERA--a program to draw schematic diagrams of protein secondary structures.
Amino acid sequence templates derived from recurrent turn motifs in proteins: critical evaluation of their predictive power.
Protein motifs and data-base searching.
Conformation of beta-hairpins in protein structures. A systematic classification with applications to modelling by homology, electron density fitting and protein engineering.
Rebuilding flavodoxin from C alpha coordinates: a test study.
Protein-protein recognition via side-chain interactions.
Protein structure. The shape of things to come?
Analysis and prediction of the different types of beta-turn in proteins.
Distributions of water around amino acid residues in proteins.
Helix geometry in proteins.
Analysis, design and modification of loop regions in proteins.
The geometries of interacting arginine-carboxyls in proteins.
Structural and sequence patterns in the loops of beta alpha beta units.
Knowledge-based prediction of protein structures and the design of novel molecules.
The distribution of charged groups in proteins.
Location of 'continuous' antigenic determinants in the protruding regions of proteins.
Continuous and discontinuous protein antigenic determinants.
Beta-hairpin families in globular proteins.
Recognition of super-secondary structure in proteins.
Ion-pairs in proteins.
Amino and carboxy-terminal regions in globular proteins.
Prediction of super-secondary structure in proteins.
Conformation of terminal regions in proteins.
Electrostatic interactions in proteins.
Disulphide bridges in globular proteins.
An analysis of the structure of triose phosphate isomerase and its comparison with lactate dehydrogenase.
Calcium binding by troponin-C. A proton magnetic resonance study.
Conformational energy calculations for dinucleotide molecules: a study of the nucleotide coenzyme nicotinamide adenine dinucleotide (NAD+).
Quantitative determination of the conformation of ATP in aqueous solution using the lanthanide cations as nuclear-magnetic-resonance probes.
Comparison of the mammalian insulin signalling pathway to invertebrates in the context of FOXO-mediated ageing.
The evolution of enzyme function in the isomerases.
MDL-1, a growth- and tumor-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C. elegans.
DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamma isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans.
Efficient photocatalytic hydrogen production by platinum-loaded carbon-doped cadmium indate nanoparticles.
Methods to Characterize the Structure of Enzyme Binding Sites:
A nuclear magnetic resonance investigation of the conformation of nicotinamide mononucleotide in aqueous solution.
Proton magnetic resonance study of troponin-C.
CATH: comprehensive structural and functional annotations for genome sequences.
Solvent-induced distortions and the curvature of alpha-helices.
An extension of secondary structure prediction towards the prediction of tertiary structure.
Depicting topology and handedness in jellyroll structures.
A mutation data matrix for transmembrane proteins.
Computer techniques for conformational studies of biological molecules.
Comparison of the calcium- and magnesium-induced structural changes of troponin--C. A proton magnetic resonance study.
Protein fold recognition.
Buried waters and internal cavities in monomeric proteins.
The application of hydrogen bonding analysis in X-ray crystallography to help orientate asparagine, glutamine and histidine side chains.
Who checks the checkers? Four validation tools applied to eight atomic resolution structures. EU 3-D Validation Network.
Iditis: protein structure database.
Design, synthesis and structure of a zinc finger with an artificial beta-turn.
Motif-based searching in TOPS protein topology databases.
COVOL: an interactive program for evaluating second virial coefficients from the triaxial shape or dimensions of rigid macromolecules.
The CATH database: an extended protein family resource for structural and functional genomics.
The European dimension for the mouse genome mutagenesis program.
Protein Evolution – Sequence, Structure and Systems
Celebrating structural biology.
Delivering ICT Infrastructure for Biomedical Research
Delivering ICT Infrastructure for Biomedical Research
The NAD Binding Domain and the Short Chain Dehydrogenase/Reductase (SDR) Superfamily
The Ramachandran Plot and Protein Structure Validation
Protein Data Resources
Variability, Modelling and Prediction of Beta-Hairpins with reference to the immunoglobulin fold
Application of Computer Graphics in the Study of Drug-Receptor Interactions
Prediction of Protein Structure from C-Alpha Atomic Coordinates
Protein Structure Analysis - A Basis for Structure Prediction
Specialist Periodical Report
The Iditis Relational Database of Protein Structure
Structural Patterns in Globular Proteins
Trypanothine Metabolism as a Target for Drug Design: Molecular Modelling of Trypanothine Reductase in Biochemical Protozoology
Modelling by Homology
Protein Structure, Prediction and Design
Modelling antibody combining sites: a review.
Protein Structure Database
Towards an understanding how side-chains pack in proteins
Atlas of Protein Side-Chain Interactions
Lessons in Analysing Protein Structures
Protein Structures: The End Point of the Folding Pathway
Secondary and Supersecondary Motifs in Protein Structures
Database Analysis for Protein Engineering
Protein Structures and Complexes - What they reveal about the interactions that stabilize them
Modelling of related protein structures
Evaluation of Protein Coordinate Data Sets
Knowledge-based validation of protein-structure coordinates derived by x-ray Cyrstallography and NMR-Spectroscopy
Software Tools for Protein Structure Analysis and Fold Classification
Modelling the Interaction of Protein Side Chains
Chirality in Proteins
Protein Engineering - Editorial Overview
Chirality in Protein Structure
Computational Approaches to Protein Ligand Interactions: Protein-heme Complexes
Protein Structure Classification
The Future of Bioinformatics
Structural genomics takes off.
Playing with Proteins
PROCHECK: Validation of Protein Structure Coordinates
Proteins, Small Molecules and Networks
Handbook of Cell Signalling
The Proteome and the Metabolome: A Structural Perspective
Binding Pocket Shape Analysis for Protein Function Prediction
Variation of geometrical and phsicochemical properties in protein binding pockets and their ligands
Evolving Methods for Macromolecular Crystallography
Methods to Characterize the Structure of Enzyme Binding Sites
The Interactoin Between Phenylalanine Rings in Proteins
A Novel-Approach for Identifying Potential Antigenic Determinants from the 3d Structure of a Protein
Interactive Map Projection
Shouldn't enantiomeric purity be included in the minimum information about a bioactive entity? Response from the MIABE group
An Ellipsoidal Approximation to Protein Shape
The Influence of Tertiary Structure on Secondary Structure Prediction - Accessiblity Versus Predictability for Beta-Structure
Sulfur-Aromatic Interactions in Proteins
Building and Design
Structure, Design and Modification of Loop Regions in Proteins
Preliminary Analysis of Water Molecule Disitributions in Proteins
Structures of Antifungal Thionin Proteins - H-1-NMR of SI-Alpha-1 from Sorghum Seeds
Progress Towards Recognizing Protein Folds from Amino-Acid-Sequence
Amino Aromatic Interactions
The Cuticular Peroxidase of Filarial Parasites - a Potential Target for Drug Design
Chain Topologies Copmatible with a Antiparallel Six-Stranded b-sandwich: Predominance of Greek Key Protein Structures
Protein Motifs and Folding Recognition
Folding of Beta Structure in Proteins
BLEEP - A Potential of Mean Force Describing Protein-Ligan Interactions: Generating the Potential
Evaluation of a Knowledge-Based Potential of Mean Force for Scoring Docked Protein-Ligand Complexes
Automatic Interence of Protein Quatenary Structure from Crystals
Proteomics: The Protein Complement of the Genome
Software Engineering Challenges in Bioinformatics
The Non-Random Loop Regions In Proteins
Prediction of Protein Tertiary Structure from C-Alpha Atomic Coordinates
Structural Survey (Review of Introduction to Proteins and Protein Engineering)
Protein Engineering '87 Conference Report
An Integrated Sequence and Structure Database
Protein Engineering and Design
Antibody Modelling - Tackling a Loopy Problem
A Compairson to Three Theoretical Approaches to the Study of Side-Chain Interactions in Proteins
Shared Structural Motif in Proteins - Reply
Protein Folds and Folding
Pattern Search over the TOPS Protein Topology Database
The Proteome and the Metabolome