John Tainer

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Elsevier - Mendeley (2018-01-01)


Prof. Tainer, Ph.D. from Duke University in structural biochemistry, Damon Runyon - Walter Winchell Fellow with Arthur Olson on computer graphics. John Tainer designed, developed, and directs the combined small angle X-ray scattering (SAXS) and macromolecular X-ray crystallography (MX) synchrotron beamline SIBYLS (Structurally Integrated BiologY for Life Sciences) at the Advanced Light Source. His current positions are Director of SIBYLS at the Advanced Light Source, visting Professor at Lawrence Berkeley National lab, Adjunct Professor at Scripps, and Professor and Robert Welch Chair in Chemistry at MD Anderson. His projects strive to understand macromolecular machines. Specific work includes MRE11 complex, RAD51 paralogues, FEN1 complexes, nucleotide excision repair, metabolic signaling by parylation plus apoptosis inducing factor, and DNA base repair complexes. He aims to provide methods and results relevant to human health and bio-manufacturing and synthetic biology. His efforts on advanced technologies focus on combined methods to determine structures, conformations and assemblies both in solution by X-ray scattering and at high resolution by crystallography and cryo-electron microscopy.
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