Thomas Liehr

ORCID iD
orcid.org/0000-0003-1672-3054
  • Country
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Germany

Sources:
Thomas Liehr (2016-01-24)

  • Keywords
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Molecular Cytogenetics,

Sources:
Thomas Liehr (2015-10-23)

Small supernumerary marker chromosomes (sSMC),

Sources:
Thomas Liehr (2015-10-23)

Uniparental disomy (UPD),

Sources:
Thomas Liehr (2015-10-23)

Heterochromatin,

Sources:
Thomas Liehr (2015-10-23)

Nuclear architecture,

Sources:
Thomas Liehr (2015-10-23)

chromosome evolution,

Sources:
Thomas Liehr (2015-10-23)

chromosome structure,

Sources:
Thomas Liehr (2015-10-23)

leukemia,

Sources:
Thomas Liehr (2015-10-23)

solid tumor,

Sources:
Thomas Liehr (2015-10-23)

acquires chromosomal changes

Sources:
Thomas Liehr (2015-10-23)

  • Websites
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Basics and literature on multicolor fluorescence in situ hybridization application.

Sources:
Thomas Liehr (2015-10-23)

Small supernumerary marker chromosomes.

Sources:
Thomas Liehr (2015-10-23)

Cases with uniparental disomy.

Sources:
Thomas Liehr (2015-10-23)

Affiliation webpage

Sources:
Thomas Liehr (2015-10-23)

  • Email
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Thomas.Liehr@med.uni-jena.de

Sources:
Thomas Liehr (2015-10-23)

i8lith@mti.uni-jena.de

Sources:
0000-0003-1672-3054 (2013-03-07)

Biography

The lab of molecular cytogenetics at the Institut für Humangenetik in Jena has different research lines, all of them connected by the interest in chromosome structure and evolution. The main research interest is within the frame of clinical genetic research, i.e. the characterization of acquired and inherited chromosomal aberrations with the aim to understand the biological background of how and why such alterations from the normal happen. There are ongoing projects on small supernumerary marker chromosomes (http://ssmc-tl.com/sSMC.html), chromosomal heteromorphisms on chromosomes 2 and 9 and fragile sites. In leukemia-research the lab is involved in the search for cryptic, disease-associated or -causing chromosomal aberrations. Besides we are interested in chromosomal evolution and have cowork with other groups working on fish-species (Brasil), turtle (Italy), or Rhodentia (Russia). Apart from multicolor fluorescence in situ hybridization (http://ssmc-tl.com/mfish.html) approaches like immunohistochemistry, microsatellite analysis (http://upd-tl.com/upd.html) or array-CGH are applied in the research.
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