Maria C. Pedroso de Lima received her Ph.D. degree in Chemistry from Imperial College of Science and Technology at the University of London in 1977 and her Habilitation (Agregação) degree in Biochemistry from the University of Coimbra in 1997. She is Full Professor and Head of the Vectors and Gene Therapy Group at the Center for Neuroscience and Cell Biology, University of Coimbra.
Her research activity has been centred on the design of novel non-viral vectors for delivery of different types of therapeutic molecules (including drugs, plasmid DNA, antisense oligonucleotides, siRNAs and miRNAs) to target tissues or cells or specific molecular targets and development of new molecular therapeutic strategies. Her research team has generated a number of animal models of cancer and neurodegenerative disorders for evaluating the potential of the developed strategies, and addressed the mechanisms on the process of nucleic acid delivery and the molecular/cellular events associated with the therapeutic response.
Maria C. Pedroso de Lima has authored and co-authored 169 full papers in peer-reviewed journals, 32 book chapters and holds 3 patents approved in USA. She has edited 2 books, one published by Springer-Verlag and the other by Translational Research Network, and was the Director of a NATO Advanced Study Institute on the trafficking of intracellular membranes and membrane fusion. She has successfully supervised/co-supervised 3 post-doctoral researchers and 24 PhD students.
She has been responsible for collaborative research projects funded by the NATO Scientific Affairs Division, European Union and the Portuguese Foundation for Science and Technology.