Personal information

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Loop profile: 2429432

Keywords

Intestinal stem cells, Nutrient Homeostasis

Activities

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Employment (1)

University of Science and Technology of China: Hefei, Anhui, CN

2019-09-01 to present | Professor (Life Science School)
Employment
Source: Self-asserted source
LI HE

Education and qualifications (4)

Harvard Medical School: Boston, MA, US

2012-05-01 to 2019-08-01 | Postdoctoral Fellow (Department of Genetics)
Qualification
Source: Self-asserted source
LI HE

Johns Hopkins University: Baltimore, MD, US

2006-08-24 to 2012-04-30 | PhD (Biological Chemistry)
Education
Source: Self-asserted source
LI HE

Tsinghua University: Beijing, Beijing, CN

2003-08 to 2006-06 | MS (Biological Science)
Education
Source: Self-asserted source
LI HE

Tsinghua University: Beijing, Beijing, CN

1999-08 to 2003-07 | BS (Chemistry)
Education
Source: Self-asserted source
LI HE

Works (27)

Addressable and perceptible dynamic reprogram of ferromagnetic soft machines

Nature Communications
2025-03-06 | Journal article
DOI: 10.1038/s41467-025-57454-w
Contributors: Yuxuan Sun; Boxi Sun; Xiang Cui; Weihua Li; Yue Zhang; Li He; Shutong Nong; Zhengqing Zhu; Jiyang Wu; Dongxiao Li et al.
Source: check_circle
Crossref

MISO Regulates Mitochondria Dynamics and mtDNA Homeostasis by Establishing Inner Membrane Subdomains

2025-01-06 | Preprint
DOI: 10.1101/2025.01.05.631328
Contributors: Yue Zhang; Yuchen Xia; Xinhui Wang; Shang Wu; Jianshuang Li; Xuan Guo; Qinghua Zhou; Li He
Source: check_circle
Crossref

Dietary amino acids promote glucagon-like hormone release to generate global calcium waves in adipose tissues in Drosophila

Nature Communications
2025-01-02 | Journal article
DOI: 10.1038/s41467-024-55371-y
Contributors: Muhammad Ahmad; Shang Wu; Shengyao Luo; Wenjia Shi; Xuan Guo; Yuansheng Cao; Norbert Perrimon; Li He
Source: check_circle
Crossref

Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue

Cellular and Molecular Life Sciences
2024-12 | Journal article
DOI: 10.1007/s00018-024-05226-y
Contributors: Meng Liu; Li He
Source: check_circle
Crossref

Protein phosphatase 1 regulates core PCP signaling

EMBO reports
2023-12-06 | Journal article
DOI: 10.15252/embr.202356997
Contributors: Song Song; Bomsoo Cho; Alexis T Weiner; Silas Boye Nissen; Irene Ojeda Naharros; Pablo Sanchez Bosch; Kaye Suyama; Yanhui Hu; Li He; Tanya Svinkina et al.
Source: check_circle
Crossref

CCDC127 regulates lipid droplet homeostasis by enhancing mitochondria-ER contacts

Biochemical and Biophysical Research Communications
2023-11 | Journal article
DOI: 10.1016/j.bbrc.2023.10.048
Contributors: Yuchen Xia; Yue Zhang; Yuwei Sun; Li He
Source: check_circle
Crossref

Synthetic Notch receptors and their applications to study cell-cell contacts in vivo

Developmental Cell
2023-02 | Journal article
DOI: 10.1016/j.devcel.2023.01.001
Part of ISSN: 1534-5807
Contributors: Li He; Norbert Perrimon
Source: Self-asserted source
LI HE

Regulation of insulin and adipokinetic hormone/glucagon production in flies

WIREs Developmental Biology
2020-03 | Journal article
DOI: 10.1002/wdev.360
Part of ISSN: 1759-7684
Part of ISSN: 1759-7692
Contributors: Muhammad Ahmad; Li He; Norbert Perrimon
Source: Self-asserted source
LI HE

A role for actomyosin contractility in Notch signaling

BMC Biology
2019-12 | Journal article
DOI: 10.1186/s12915-019-0625-9
Part of ISSN: 1741-7007
Contributors: Ginger Hunter; Li He; Norbert Perrimon; Guillaume Charras; Edward Giniger; Buzz Baum
Source: Self-asserted source
LI HE

In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer

eLife
2019-05-29 | Journal article
DOI: 10.7554/eLife.46181
Contributors: Li He; Richard Binari; Jiuhong Huang; Julia Falo-Sanjuan; Norbert Perrimon
Source: check_circle
Crossref

Mechanosensitive channels and their functions in stem cell differentiation

Experimental Cell Research
2019-01 | Journal article
DOI: 10.1016/j.yexcr.2018.11.016
Part of ISSN: 0014-4827
Contributors: Li He; Muhammad Ahmad; Norbert Perrimon
Source: Self-asserted source
LI HE

Intestinal Stem Cells Exhibit Conditional Circadian Clock Function

Stem Cell Reports
2018-11 | Journal article
DOI: 10.1016/j.stemcr.2018.10.010
Part of ISSN: 2213-6711
Contributors: Kathyani Parasram; Nathaniel Bernardon; Maha Hammoud; Hanna Chang; Li He; Norbert Perrimon; Phillip Karpowicz
Source: Self-asserted source
LI HE

Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel

Nature
2018-03 | Journal article
DOI: 10.1038/nature25744
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Contributors: Li He; Guangwei Si; Jiuhong Huang; Aravinthan D. T. Samuel; Norbert Perrimon
Source: Self-asserted source
LI HE

Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+ signaling in the Drosophila midgut

eLife
2017-05-31 | Journal article
DOI: 10.7554/elife.22441
Part of ISSN: 2050-084X
Contributors: Chiwei Xu; Junjie Luo; Li He; Craig Montell; Norbert Perrimon
Source: Self-asserted source
LI HE

Development of an optimized synthetic Notch receptor as an in vivo cell–cell contact sensor

Proceedings of the National Academy of Sciences
2017-05-23 | Journal article
DOI: 10.1073/pnas.1703205114
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Li He; Jiuhong Huang; Norbert Perrimon
Source: Self-asserted source
LI HE

Coordinated control of Notch-Delta signalling and cell cycle progression drives lateral inhibition mediated tissue patterning

Development
2016-01-01 | Journal article
DOI: 10.1242/dev.134213
Part of ISSN: 1477-9129
Part of ISSN: 0950-1991
Contributors: Ginger Hunter; Zena Hadjivasiliou; Hope Bonin; Li He; Norbert Perrimon; Guillaume Charras; Buzz Baum
Source: Self-asserted source
LI HE

Border Cell Migration: A Model System for Live Imaging and Genetic Analysis of Collective Cell Movement

Methods in Molecular Biology
2015 | Book chapter
DOI: 10.1007/978-1-4939-2851-4_6
Part of ISBN: 9781493928507
Part of ISBN: 9781493928514
Part of ISSN: 1064-3745
Part of ISSN: 1940-6029
Contributors: Mohit Prasad; Xiaobo Wang; Li He; Danfeng Cai; Denise J. Montell
Source: Self-asserted source
LI HE

Proteomic mapping in live <i>Drosophila</i> tissues using an engineered ascorbate peroxidase

Proceedings of the National Academy of Sciences
2015-09-29 | Journal article
DOI: 10.1073/pnas.1515623112
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Contributors: Chiao-Lin Chen; Yanhui Hu; Namrata D. Udeshi; Thomas Y. Lau; Frederik Wirtz-Peitz; Li He; Alice Y. Ting; Steven A. Carr; Norbert Perrimon
Source: Self-asserted source
LI HE

Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch

Developmental Cell
2015-06 | Journal article
DOI: 10.1016/j.devcel.2015.05.004
Part of ISSN: 1534-5807
Contributors: Wendy R. Gordon; Brandon Zimmerman; Li He; Laura J. Miles; Jiuhong Huang; Kittichoat Tiyanont; Debbie G. McArthur; Jon C. Aster; Norbert Perrimon; Joseph J. Loparo et al.
Source: Self-asserted source
LI HE

Mechanochemical regulation of oscillatory follicle cell dynamics in the developing <i>Drosophila</i> egg chamber

Molecular Biology of the Cell
2014-11-05 | Journal article
DOI: 10.1091/mbc.e14-04-0875
Part of ISSN: 1059-1524
Part of ISSN: 1939-4586
Contributors: Sarita Koride; Li He; Li-Ping Xiong; Ganhui Lan; Denise J. Montell; Sean X. Sun
Source: Self-asserted source
LI HE

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

Cell
2014-05 | Journal article
DOI: 10.1016/j.cell.2014.03.045
Part of ISSN: 0092-8674
Contributors: Danfeng Cai; Shann-Ching Chen; Mohit Prasad; Li He; Xiaobo Wang; Valerie Choesmel-Cadamuro; Jessica K. Sawyer; Gaudenz Danuser; Denise J. Montell
Source: Self-asserted source
LI HE

A cellular sense of touch

Nature Cell Biology
2012-09 | Journal article
DOI: 10.1038/ncb2572
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Contributors: Li He; Denise Montell
Source: Self-asserted source
LI HE

Spatiotemporal Control of Small GTPases with Light Using the LOV Domain

Methods in Enzymology
2011 | Book chapter
DOI: 10.1016/b978-0-12-385075-1.00016-0
Part of ISSN: 0076-6879
Contributors: Yi I. Wu; Xiaobo Wang; Li He; Denise Montell; Klaus M. Hahn
Source: Self-asserted source
LI HE

Shining light on Drosophila oogenesis: live imaging of egg development

Current Opinion in Genetics &amp; Development
2011-10 | Journal article
DOI: 10.1016/j.gde.2011.08.011
Part of ISSN: 0959-437X
Contributors: Li He; Xiaobo Wang; Denise J Montell
Source: Self-asserted source
LI HE

A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension

Molecular Biology of the Cell
2011-07-15 | Journal article
DOI: 10.1091/mbc.e11-05-0411
Part of ISSN: 1059-1524
Part of ISSN: 1939-4586
Contributors: Jessica K. Sawyer; Wangsun Choi; Kuo-Chen Jung; Li He; Nathan J. Harris; Mark Peifer
Source: Self-asserted source
LI HE

Tissue elongation requires oscillating contractions of a basal actomyosin network

Nature Cell Biology
2010-12 | Journal article
DOI: 10.1038/ncb2124
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Contributors: Li He; Xiaobo Wang; Ho Lam Tang; Denise J. Montell
Source: Self-asserted source
LI HE

Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo

Nature Cell Biology
2010-06 | Journal article
DOI: 10.1038/ncb2061
Part of ISSN: 1465-7392
Part of ISSN: 1476-4679
Contributors: Xiaobo Wang; Li He; Yi I. Wu; Klaus M. Hahn; Denise J. Montell
Source: Self-asserted source
LI HE

Peer review (7 reviews for 5 publications/grants)

Review activity for Cell discovery. (1)
Review activity for Cell reports. (1)
Review activity for Current biology. (1)
Review activity for Developmental cell. (3)
Review activity for Oncogene. (1)
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