Personal information

Retrotransposon, Somatic mosaicism, Antisense oligonucleotides, Genomic medicine
China

Activities

Employment (4)

Boston Children's Hospital: Boston, Massachusetts, US

2018-08 to present | Research Fellow (Dr. Eunjung Alice Lee's Lab) (Genetics and Genomics)
Employment
Source: Self-asserted source
Boxun Zhao

Boston Children's Hospital: Boston, Massachusetts, US

2018-08 to present | Research Fellow (Dr. Timothy W. Yu's Lab) (Genetics and Genomics)
Employment
Source: Self-asserted source
Boxun Zhao

National Institute of Biological Sciences Beijing: Beijing, CN

2017-07 to 2018-07 | Post-doc (Dr. Meng-Qiu Dong's lab)
Employment
Source: Self-asserted source
Boxun Zhao

National Institute of Biological Sciences Beijing: Beijing, CN

2012-09 to 2017-07 | Ph.D. Candidate (Dr. Liping Wei's Lab)
Employment
Source: Self-asserted source
Boxun Zhao

Education and qualifications (3)

Peking Union Medical College at Tsinghua University: Beijing, CN

2012-09 to 2017-07 | Ph.D. (Genetics)
Education
Source: Self-asserted source
Boxun Zhao

National Institute of Biological Sciences, Beijing: Beijing, CN

2012-09 to 2017-07 | PhD in Genetics (Dr. Liping Wei's Lab)
Education
Source: Self-asserted source
Boxun Zhao

Hunan Normal University: Changsha, Hunan, CN

2008-09 to 2012-07 | B. S. (Biological Sciences)
Education
Source: Self-asserted source
Boxun Zhao

Professional activities (4)

American Society of Human Genetics: Bethesda, Maryland, US

2021-11-19 to present | Member
Membership
Source: Self-asserted source
Boxun Zhao

Manton Center for Orphan Disease Research, Boston Children's Hospital: Boston, Massachusetts, US

2018-10 to present | Fellow
Membership
Source: Self-asserted source
Boxun Zhao

American College of Medical Genetics and Genomics: Bethesda, MD, US

2021-11-01 to 2022-11-01
Membership
Source: Self-asserted source
Boxun Zhao

ACMG Foundation for Genetic and Genomic Medicine: Bethesda, Maryland, US

2022-03-24 | David L. Rimoin Inspiring Excellence Award (The 2022 ACMG Annual Clinical Genetics Meeting)
Distinction
Source: Self-asserted source
Boxun Zhao

Funding (2)

Structural variants in rare disease: discovery, interpretation, and therapeutics

2020-07 to 2022-06 | Salary award
Manton Center for Orphan Disease Research, Boston Children's Hospital (Boston, MA, US)
GRANT_NUMBER: 2 awardees (2020)
Source: Self-asserted source
Boxun Zhao

Pathogenic structural variant identification and splicing defect correction

2018-10 to 2019-10 | Award
Manton Center for Orphan Disease Research, Boston Children's Hospital (Boston, MA, US)
GRANT_NUMBER: 2 awardees (2018)
Source: Self-asserted source
Boxun Zhao

Works (17)

A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders

Nature Communications
2024-09-27 | Journal article
Contributors: Arthur S. Lee; Lauren J. Ayers; Michael Kosicki; Wai-Man Chan; Lydia N. Fozo; Brandon M. Pratt; Thomas E. Collins; Boxun Zhao; Matthew F. Rose; Alba Sanchis-Juan et al.
Source: check_circle
Crossref

Human cytomegalovirus harnesses host L1 retrotransposon for efficient replication

Nature Communications
2024-09-02 | Journal article
Contributors: Sung-Yeon Hwang; Hyewon Kim; Danielle Denisko; Boxun Zhao; Dohoon Lee; Jiseok Jeong; Jinuk Kim; Kiwon Park; Junhyun Park; Dongjoon Jeong et al.
Source: check_circle
Crossref

Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer’s disease microglia

2024-01-04 | Preprint
Contributors: August Yue Huang; Zinan Zhou; Maya Talukdar; Michael B. Miller; Brian Chhouk; Liz Enyenihi; Ila Rosen; Edward Stronge; Boxun Zhao; Dachan Kim et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders

medRxiv
2023 | Other
EID:

2-s2.0-85182645122

Contributors: Lee, A.S.; Ayers, L.J.; Kosicki, M.; Chan, W.-M.; Fozo, L.N.; Pratt, B.M.; Collins, T.E.; Zhao, B.; Rose, M.F.; Sanchis-Juan, A. et al.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier

Contribution and therapeutic implications of retroelement insertions in ataxia telangiectasia

American Journal of Human Genetics
2023 | Journal article
EID:

2-s2.0-85174706843

Part of ISSN: 15376605 00029297
Contributors: Zhao, B.; Nguyen, M.A.; Woo, S.; Kim, J.; Yu, T.W.; Lee, E.A.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

A framework for individualized splice-switching oligonucleotide therapy

Nature
2023-07-27 | Journal article
Contributors: Jinkuk Kim; Sijae Woo; Claudio M. de Gusmao; Boxun Zhao; Diana H. Chin; Renata L. DiDonato; Minh A. Nguyen; Tojo Nakayama; Chunguang April Hu; Aubrie Soucy et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

A neurodevelopmental disorder caused by a novel de novo SVA insertion in exon 13 of the SRCAP gene

European Journal of Human Genetics
2022-09 | Journal article
Contributors: Boxun Zhao; Jill A. Madden; Jasmine Lin; Gerard T. Berry; Monica H. Wojcik; Xuefang Zhao; Harrison Brand; Michael Talkowski; Eunjung Alice Lee; Pankaj B. Agrawal
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior

Genetics in Medicine
2021 | Journal article
EID:

2-s2.0-85102065834

Part of ISSN: 15300366 10983600
Contributors: Harris, H.K.; Nakayama, T.; Lai, J.; Zhao, B.; Argyrou, N.; Gubbels, C.S.; Soucy, A.; Genetti, C.A.; Suslovitch, V.; Rodan, L.H. et al.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier

Genomic approaches to trace the history of human brain evolution with an emerging opportunity for transposon profiling of ancient humans

Mobile DNA
2021 | Journal article
EID:

2-s2.0-85117570049

Part of ISSN: 17598753
Contributors: Wang, Y.; Zhao, B.; Choi, J.; Lee, E.A.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

APPgene copy number changes reflect exogenous contamination

Nature
2020 | Journal article
EID:

2-s2.0-85089581892

Part of ISSN: 14764687 00280836
Contributors: Kim, J.; Zhao, B.; Huang, A.Y.; Miller, M.B.; Lodato, M.A.; Walsh, C.A.; Lee, E.A.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

Identification and Genotyping of Transposable Element Insertions From Genome Sequencing Data

Current Protocols in Human Genetics
2020 | Journal article
EID:

2-s2.0-85088031283

Part of ISSN: 19348258 19348266
Contributors: Chu, C.; Zhao, B.; Park, P.J.; Lee, E.A.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

Disruption of RFX family transcription factors causes autism, attention deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior

2020-09-13 | Other
Contributors: Holly K. Harris; Tojo Nakayama; Jenny Lai; Boxun Zhao; Nikoleta Argyrou; Cynthia S. Gubbels; Aubrie Soucy; Casie A. Genetti; Lance H. Rodan; George E. Tiller et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals

PLoS Genetics
2019 | Journal article
EID:

2-s2.0-85065348190

Part of ISSN: 15537404 15537390
Contributors: Zhao, B.; Wu, Q.; Ye, A.Y.; Guo, J.; Zheng, X.; Yang, X.; Yan, L.; Liu, Q.-R.; Hyde, T.M.; Wei, L. et al.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

Evidence that APP gene copy number changes reflect recombinant vector contamination

2019-07-22 | Other
Contributors: Junho Kim; Boxun Zhao; August Yue Huang; Michael B. Miller; Michael A. Lodato; Christopher A. Walsh; Eunjung Alice Lee
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals

2018-12-31 | Other
Contributors: Boxun Zhao; Qixi Wu; Adam Yongxin Ye; Jing Guo; Xianing Zheng; Xiaoxu Yang; Linlin Yan; Qing-Rong Liu; Thomas M. Hyde; Liping Wei et al.
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Postzygotic single-nucleotide mosaicisms contribute to the etiology of autism spectrum disorder and autistic traits and the origin of mutations

Human Mutation
2017 | Journal article
EID:

2-s2.0-85019708816

Contributors: Dou, Y.; Yang, X.; Li, Z.; Wang, S.; Zhang, Z.; Ye, A.Y.; Yan, L.; Yang, C.; Wu, Q.; Li, J. et al.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎

Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals

Cell Research
2014 | Journal article
EID:

2-s2.0-84908552190

Contributors: Huang, A.Y.; Xu, X.; Ye, A.Y.; Wu, Q.; Yan, L.; Zhao, B.; Yang, X.; He, Y.; Wang, S.; Zhang, Z. et al.
Source: Self-asserted source
Boxun Zhao via Scopus - Elsevier
grade
Preferred source (of 2)‎