Eduard Batlle is ICREA Senior Research Professor, Head of the Colorectal Cancer laboratory and Coordinator of the Oncology program at the Institute for Research in Biomedicine (IRB Barcelona, Spain), since 2004.
1993 BSc. Universitat de Barcelona.
1994-1999 PhD fellow at Institut Municipal de Investigació Mèdica (IMIM).
1999 Associate professor in Biochemistry –Life Sciences at the Pompeu Fabra University, Barcelona.
1999- 2000 PostDoctoral Fellow at Miguel Beato’s group- Institut für Molekularbiologie und Tumorforschung, Marburg. Germany.
2000-2004: PostDoctoral Fellow at Hans Clevers Lab, Netherlands Institute for Developmental Biology, Utrecht, NL.
ERC-Advance Grant (2013)
ERC-Proof of Concept (2014)
ERC- Starting Grant (2007)
Medalla de la Fundación Internacional Olof Palme (2018)
Fundación Francisco Cobos Award (2017)
Fundación Carmen y Severo Ochoa Award (2016)
Lilly Foundation National Award (2016)
XI Premio Ciencias de la Salud Fundación Caja Rural de Granada (2015)
EACR-Pezcoller Award (2014)
Josef Steiner Cancer Research Award (2013)
Drs. Diz Pintado Award (2013)
Banc de Sabadell Award for Biomedical Research (2010)
Debiopharm Life science award (2006)
Batlle’s research activity is focused on the characterization of the mechanisms that drive colorectal cancer initiation and progression. The group pioneers research connecting the biology of intestinal stem cells with that of their tumor counterparts, the so-called cancer stem cells. We are also interested in the mechanisms that drive metastasis formation and we have described the critical role of the tumor microenvironment on metastasis formation. This discovery represents the basis for translational projects aiming to improve diagnosis and treatment of CRC patients. Previous works on EPH signaling founded the field of research on EPHs and ephrins in cancer. In addition, we originally discovered the transcription factor Snail as a suppressor of E-cadherin expression in tumor cells, a discovery that founded the research field on Epithelial to Mesenchymal Transition (EMT) in cancer.