INFECTIOUS STRATEGIES OF ANAPLASMATACEAE
I have worked on numerous whole genome sequencing projects and functional genomics projects for Xanthomonas campestris pv. campestris, X. c. pv. raphani, X. oryzae pv. oryzae, X. o. pv. oryzicola and Ehrlichia ruminantium. My current research interests are directed toward understanding host-microbe interactions.
Pathogens exploit a wide array of strategies to facilitate infection in mammalian hosts. For obligate intracellular pathogens, there is a constant need to manipulate signaling pathways in the host cell. I am particularly interested in the pathways used by intracellular bacteria to enter host cells and create a safe replicating niche. My research encompasses the underlying molecular mechanisms of these processes and the illumination of how these strategies facilitate unique interactions with the host immune system, most notably for immune evasion.