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Biography
I received a Ph.D. in chemistry in 1991 from the Freie Universität Berlin, inventing with Prof. J. Mulzer the Cr(II) mediated addition of chiral allyl bromides to aldehydes (Hiyama-reaction) and applied this method in natural product synthesis. In the course of a postdoctoral study from 1991 to 1993 at the medicinal chemistry department of Hoffmann-La Roche, Nutley, NJ, USA with Dr. M. Uskokovic, I invented a new method for the synthesis of vitamin D metabolites and steroids by a stereoselective Pausen-Khand-reaction. In 1993 I joined the pharmaceutical chemistry department of the Universität des Saarlandes (Prof. R. Hartmann), where I was involved with the development of new 5-α reductase inhibitors considered as potential drugs against hormone mediated prostate cancer. Before founding the CRO Endotherm, I was appointed as a senior consultant in a consultancy company in Düsseldorf, where I was involved with public fundraising for medium sized enterprises.
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LSHM-CT-2005-018833