Dr. Paul Clarke began his career at the University of Bath where he obtained his B.Sc(Hons) in 1993. He remained at Bath to study the utility and mechanism of intramolecular dioxirane epoxidation reactions under the supervision of Dr. A. Armstrong. In 1996, he obtained his Ph.D and moved to Florida State University where he spent two years working with Prof. R. A. Holton on the synthesis and functionalisation of taxane ring systems. In 1999, he returned to the UK to work on a carbenoid insertion approach to peptide synthesis with Prof. C. J. Moody at the University of Exeter. In September 1999, he was appointed as a lecturer in Organic Chemistry at the University of Nottingham. In January 2006, he moved to the University of York as a Senior Lecturer and then later was promoted to Reader. In 2009 he was admitted as a Fellow of the Royal Society of Chemistry. Paul was a visiting academic at Universidad Complutense, Madrid, Spain in 2010 and 2011 and was an EPSRC funded research visiting fellow to the Research School of Chemistry, Australian National University in 2018. From 2013-2017 he was on the editorial board of the international Open Access Journal Advances in Chemistry and from Jan 2013 to Dec 2015 he was Chair of the Department of Chemistry's Graduate School. Paul is currently on the editorial board of the journal Life and acts as a chemistry consultant for Vertex Pharmaceuticals. From 2010, Paul has been a member of the Yorkshire and Humber SCI Regional Committee.