Changes in the T-helper cytokine profile and in lymphocyte activation at the systemic and local levels in women with endometriosis
Mechanisms regulating invasiveness and growth of endometriosis lesions in rat experimental model and in humans
Antsiferova Y., Sotnikova N. The local immune mechanisms involved in the formation of endometriotic lesions. In: Endometriosis - Basis Concepts and Current Research Trends, Edited by Koel Chaudhury abd Baidyanath Chakravarth, published by InTech
Changes of the functional state of peritoneal macrophages and the expression of mRNAs of some genes, regulating apoptosis and invasiveness, in the endometrial tissue of women with endometriosis are demonstrated.
Silica Nanoparticles as Drug Delivery System for Immunomodulator GMDP /E.V. Parfenyuk, N.A. Alyoshina, Yu.S. Antsiferova, N.Yu. Sotnikova // 2012, ASME, 3 Park Avenue, New York, NY 10016, USA, 82 р
The process of topical delivery of immunomodulatory drug GMDP into the peritoneal macrophages using silica nanoparticles as nanocarries is described.
Kulikova GA, Parfenyuk EV, Ryabinina IV, Antsiferova YuS, Sotnikova NYu , Posiseeva LV, Eliseeva MA. In vitro studies of interaction of modiﬁed silica nanoparticles with different types of immunocompetent cells. J Biomed Mater Res: A 2010; 95A: 434-439.
Interaction between silica nanoparticles and different types of immunocompetent cells (peritoneal lymphocytes and macrophages) was studied.
Mincheva-Nilsson L., Nagaeva O., Chen T., Stendahl U., Antsiferova J., Mogren I., Hernestal J., Baranov V. Placenta-derived soluble MHC class I chain-related molecules down-regulate NKG2D receptor on peripheral blood mononuclear cells during human pregnancy: a possible novel immune escape mechanism for fetal survival//J.Immunol.-2006.-V.176.-N6.-P.3585-3592.
The role of NK receptors NKG2D and its ligands MICA/B in the pregnancy development is discuss.