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Scopus Author ID: 38561784300
ResearcherID: N-8094-2018

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Employment (5)

St. Jude Children's Research Hospital: Memphis, US

2024-04 to present | Associate Member (Bone Marrow Transplantation and Cellular Therapy)
Employment
Source: Self-asserted source
Giedre Krenciute

St. Jude Children's Research Hospital: Memphis, TN, US

2019-08 to 2024-03 | Assistant Member (Bone Marrow Transplantation and Cellular Therapy)
Employment
Source: Self-asserted source
Giedre Krenciute

St. Jude Children's Research Hospital: Memphis, TN, US

2017-07-17 to 2019-08 | Instructor (Bone Marrow Transplantation and Cellular Therapy)
Employment
Source: Self-asserted source
Giedre Krenciute

Baylor College of Medicine: Houston, TX, US

2016-12-01 to 2017-07-16 | Instructor (Pediatrics)
Employment
Source: Self-asserted source
Giedre Krenciute

Baylor College of Medicine: Houston, TX, US

2013-11-18 to 2016-12-01 | Postdoc (Pediatrics)
Employment
Source: Self-asserted source
Giedre Krenciute

Education and qualifications (2)

Baylor College of Medicine: Houston, TX, US

2008-08-01 to 2013-11-15 | PhD (Biochemistry and Molecular Biology)
Education
Source: Self-asserted source
Giedre Krenciute

Vilnius University: Vilnius, LT

2003-09-01 to 2007-07-01 | BS (Chemistry/Biochemistry)
Education
Source: Self-asserted source
Giedre Krenciute

Works (28)

Therapeutic advantage of combinatorial chimeric antigen receptor T cell and chemotherapies

Pharmacological Reviews
2025-01 | Journal article
DOI: 10.1124/pharmrev.124.001070
Contributors: Meghan B. Ward; Amber B. Jones; Giedre Krenciute
Source: check_circle
Crossref

The Mechanisms of Altered Blood–Brain Barrier Permeability in CD19 CAR T–Cell Recipients

International Journal of Molecular Sciences
2024-01-04 | Journal article
DOI: 10.3390/ijms25010644
Contributors: Soniya N. Pinto; Giedre Krenciute
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Synapse-tuned CARs enhance immune cell anti-tumor activity

Nature Biotechnology
2023-10 | Journal article
DOI: 10.1038/s41587-022-01650-2
Contributors: Peter J. Chockley; Jorge Ibanez-Vega; Giedre Krenciute; Lindsay J. Talbot; Stephen Gottschalk
Source: check_circle
Crossref

Data from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.c.6550398
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

Data from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.c.6550398.v1
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

Supplementary Figures 1-10 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.22543758
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

Supplementary Figures 1-10 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.22543758.v1
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

Supplementary Figures 11-18 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.22543755
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

Supplementary Figures 11-18 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

2023-04-04 | Preprint
DOI: 10.1158/2326-6066.22543755.v1
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

CD47 expression is critical for CAR T-cell survival in vivo

Journal for ImmunoTherapy of Cancer
2023-03 | Journal article
DOI: 10.1136/jitc-2022-005857
Contributors: Alex N Beckett; Peter Chockley; Shondra M Pruett-Miller; Phuong Nguyen; Peter Vogel; Heather Sheppard; Giedre Krenciute; Stephen Gottschalk; Christopher DeRenzo
Source: check_circle
Crossref

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours

Nature Reviews Clinical Oncology
2023-01 | Journal article
DOI: 10.1038/s41571-022-00704-3
Contributors: Christian L. Flugel; Robbie G. Majzner; Giedre Krenciute; Gianpietro Dotti; Stanley R. Riddell; Dimitrios L. Wagner; Mohamed Abou-el-Enein
Source: check_circle
Crossref

Augmenting CAR NK cell Anti-tumor Activity by Synapse Tuning

2022-10-26 | Preprint
DOI: 10.1101/2022.10.26.512898
Contributors: Peter J Chockley; Jorge Ibanez-Vega; Giedre Krenciute; Lindsay J Talbot; Stephen Gottschalk
Source: check_circle
Crossref

Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin

Cancer Immunology Research
2021-03-01 | Journal article
DOI: 10.1158/2326-6066.CIR-20-0280
Contributors: Jessica Wagner; Elizabeth Wickman; Timothy I. Shaw; Alejandro Allo Anido; Deanna Langfitt; Jinghui Zhang; Shaina N. Porter; Shondra M. Pruett-Miller; Heather Tillman; Giedre Krenciute et al.
Source: check_circle
Crossref

MyD88/CD40 signaling retains CAR T cells in a less differentiated state

JCI Insight
2020-11-05 | Journal article
DOI: 10.1172/jci.insight.136093
Contributors: Brooke Prinzing; Patrick Schreiner; Matthew Bell; Yiping Fan; Giedre Krenciute; Stephen Gottschalk
Source: check_circle
Crossref

CRISPR-Mediated Non-Viral Site-Specific Gene Integration and Expression in T Cells: Protocol and Application for T-Cell Therapy

Cancers
2020-06-26 | Journal article
DOI: 10.3390/cancers12061704
Contributors: Zelda Odé; Jose Condori; Nicolas Peterson; Sheng Zhou; Giedre Krenciute
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity.

Nature biotechnology
2020-06-15 | Journal article
DOI: 10.1038/s41587-020-0555-7
PMID: 32541958
Source: Self-asserted source
Giedre Krenciute

Next Generation CAR T Cells for the Immunotherapy of High-Grade Glioma.

Frontiers in oncology
2019-02-26 | Journal article
PMID: 30863720
Source: Self-asserted source
Giedre Krenciute

The Landscape of CAR T Cells Beyond Acute Lymphoblastic Leukemia for Pediatric Solid Tumors.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
2018-05-01 | Journal article
DOI: 10.1200/edbk_200773
PMID: 30231350
Source: Self-asserted source
Giedre Krenciute

CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

Expert review of anticancer therapy
2018-03-16 | Journal article
DOI: 10.1080/14737140.2018.1451749
PMID: 29533108
PMC: PMC6191291
Source: Self-asserted source
Giedre Krenciute

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma.

Molecular therapy : the journal of the American Society of Gene Therapy
2018-02-08 | Journal article
DOI: 10.1016/j.ymthe.2018.02.001
PMID: 29503195
PMC: PMC6079480
Source: Self-asserted source
Giedre Krenciute

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma.

Molecular therapy. Methods & clinical development
2018-02-02 | Journal article
PMID: 29552579
Source: Self-asserted source
Giedre Krenciute

Transgenic expression of IL15 improves antiglioma activity of IL13Rα2-CAR T cells but results in antigen loss variants

Cancer Immunology Research
2017 | Journal article
DOI: 10.1158/2326-6066.CIR-16-0376
EID:

2-s2.0-85021919065
Contributors: Krenciute, G.; Prinzing, B.L.; Yi, Z.; Wu, M.-F.; Liu, H.; Dotti, G.; Balyasnikova, I.V.; Gottschalk, S.
Source: Self-asserted source
Giedre Krenciute via Scopus - Elsevier
grade
Preferred source (of 2)‎

Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies.

Cancer immunology research
2017-10-27 | Journal article
DOI: 10.1158/2326-6066.cir-17-0126
PMID: 29079655
PMC: PMC5963729
Source: Self-asserted source
Giedre Krenciute

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.

Cell reports
2017-10-01 | Journal article
DOI: 10.1016/j.celrep.2017.09.015
PMID: 28978471
PMC: PMC5645034
Source: Self-asserted source
Giedre Krenciute

Inducible activation of MyD88 and CD40 in CAR T-cells results in controllable and potent antitumor activity in preclinical solid tumor models

Cancer Discovery
2017-08-11 | Journal article
DOI: 10.1158/2159-8290.cd-17-0263
Contributors: Melinda Mata; Claudia Gerken; Phuong Nguyen; Giedre Krenciute; David M. Spencer; Stephen Gottschalk
Source: Self-asserted source
Giedre Krenciute via Crossref Metadata Search

Characterization and functional analysis of scFv-based chimeric antigen receptors to redirect T Cells to IL13Rα2-positive glioma

Molecular Therapy
2016 | Journal article
DOI: 10.1038/mt.2015.199
EID:

2-s2.0-84959525977
Contributors: Krenciute, G.; Krebs, S.; Torres, D.; Wu, M.-F.; Liu, H.; Dotti, G.; Li, X.-N.; Lesniak, M.S.; Balyasnikova, I.V.; Gottschalk, S.
Source: Self-asserted source
Giedre Krenciute via Scopus - Elsevier

Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death

Journal of Biological Chemistry
2013 | Journal article
DOI: 10.1074/jbc.M112.443416
EID:

2-s2.0-84880059173
Contributors: Krenciute, G.; Liu, S.; Yucer, N.; Shi, Y.; Ortiz, P.; Liu, Q.; Kim, B.-J.; Odejimi, A.O.; Leng, M.; Qin, J. et al.
Source: Self-asserted source
Giedre Krenciute via Scopus - Elsevier
grade
Preferred source (of 2)‎

Analysis of the human endogenous coregulator complexome.

Cell
2011-05-01 | Journal article
DOI: 10.1016/j.cell.2011.05.006
PMID: 21620140
PMC: PMC3131083
Source: Self-asserted source
Giedre Krenciute

Peer review (42 reviews for 17 publications/grants)

Review activity for ACS synthetic biology. (1)
Review activity for Acta neuropathologica communications. (1)
Review activity for Cell reports medicine. (10)
Review activity for Cell systems. (1)
Review activity for CNS drugs. (1)
Review activity for Communications biology. (1)
Review activity for EBioMedicine. (3)
Review activity for Journal for immunotherapy of cancer. (1)
Review activity for Journal of clinical neuroscience. (1)
Review activity for Journal of molecular liquids. (1)
Review activity for Molecular therapy (4)
Review activity for Nature biotechnology. (2)
Review activity for Nature communications (6)
Review activity for Nature immunology. (1)
Review activity for Neuro-oncology. (5)
Review activity for npj precision oncology. (1)
Review activity for Science translational medicine. (2)
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