Antibodies, Protein Therapeutics, Protein Solubility,
michael Doyle (2016-05-06)
Biophysical Chemistry, Calorimetry, Surface Plasmon Resonance, Protein Stability
michael Doyle (2014-02-27)
Michael Doyle, Ph.D. is Sr. Principle Investigator in Protein Science and Structure at Bristol-Myers Squibb Research and Development. His team is responsible for expression, purification and biophysical characterization of discovery-stage protein therapeutic candidates and critical protein reagents. Mike earned his PhD in Protein Biophysical Chemistry at the University of Colorado Boulder, and trained as Post-Doctoral Fellow in Protein Biophysical Chemistry at Washington University School of Medicine. His research interests include characterization of the self-association and stability of proteins, quantitative molecular interaction analysis by Surface Plasmon Resonance and Isothermal Titration Calorimetry, and recombinant protein production. In 1997 Mike was awarded the Sunner Young Scientist Award for Thermochemistry. In 2008-2009 he served as President of the Association of Biomolecular Resource Facilities (ABRF). Mike has nearly 80 scientific articles pertaining to protein biophysical characterization, and is on the editorial board of the Journal of Biomolecular Techniques.