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Works (31)

Ethanol Disrupts the Protective Crosstalk Between Macrophages and HBV-Infected Hepatocytes

Biomolecules
2025-01-03 | Journal article
DOI: 10.3390/biom15010057
Contributors: Murali Ganesan; Anup S. Pathania; Grace Bybee; Kusum K. Kharbanda; Larisa Y. Poluektova; Natalia A. Osna
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Lipid droplet‐associated proteins in alcohol‐associated fatty liver disease: A proteomic approach

Alcohol, Clinical and Experimental Research
2024-11 | Journal article
DOI: 10.1111/acer.15446
Contributors: Sathish Kumar Perumal; Le Z. Day; Madan Kumar Arumugam; Srinivas Chava; Vikas Kumar; Natalia A. Osna; Jon Jacobs; Karuna Rasineni; Kusum K. Kharbanda
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Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression

Biomolecules
2024-03 | Journal article | Author
DOI: 10.3390/biom14040404
Contributors: Natalia Osna; Irina Tikhanovich; Martí Ortega-Ribera; Sebastian Mueller; Chaowen Zheng; Johannes Mueller; Siyuan Li; Sadatsugu Sakane; Raquel Carvalho Gontijo Weber; Hyun Young Kim et al.
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Multidisciplinary Digital Publishing Institute

Mitochondrial Dysfunction-Associated Mechanisms in the Development of Chronic Liver Diseases

Biology
2023-10-05 | Journal article
DOI: 10.3390/biology12101311
Contributors: Madan Kumar Arumugam; Thiyagarajan Gopal; Rakhee Rathnam Kalari Kandy; Lokesh Kumar Boopathy; Sathish Kumar Perumal; Murali Ganesan; Karuna Rasineni; Terrence M. Donohue, Jr.; Natalia A. Osna; Kusum K. Kharbanda
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Lipidomic Analysis of Liver Lipid Droplets after Chronic Alcohol Consumption with and without Betaine Supplementation

Biology
2023-03-16 | Journal article
DOI: 10.3390/biology12030462
Contributors: Madan Kumar Arumugam; Sathish Kumar Perumal; Karuna Rasineni; Terrence M. Donohue, Jr.; Natalia A. Osna; Kusum K. Kharbanda
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Hepatocyte-Specific Triggering of Hepatic Stellate Cell Profibrotic Activation by Apoptotic Bodies: The Role of Hepatoma-Derived Growth Factor, HIV, and Ethanol

International Journal of Molecular Sciences
2023-03-10 | Journal article
DOI: 10.3390/ijms24065346
Contributors: Moses New-Aaron; Siva Sankar Koganti; Murali Ganesan; Sharma Kanika; Vikas Kumar; Weimin Wang; Edward Makarov; Kusum K. Kharbanda; Larisa Y. Poluektova; Natalia A. Osna
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A Pathogenic Role of Non-Parenchymal Liver Cells in Alcohol-Associated Liver Disease of Infectious and Non-Infectious Origin

Biology
2023-02-06 | Journal article
DOI: 10.3390/biology12020255
Contributors: Kusum K. Kharbanda; Shilpa Chokshi; Irina Tikhanovich; Steven A. Weinman; Moses New-Aaron; Murali Ganesan; Natalia A. Osna
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Role of the ghrelin system in alcohol use disorder and alcohol‐associated liver disease: A narrative review

Alcoholism: Clinical and Experimental Research
2022-12 | Journal article
DOI: 10.1111/acer.14967
Contributors: Kusum K. Kharbanda; Mehdi Farokhnia; Sara L. Deschaine; Raghav Bhargava; Marcela Rodriguez‐Flores; Carol A. Casey; Anthony P. Goldstone; Elisabet Jerlhag; Lorenzo Leggio; Karuna Rasineni
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Pathogenesis of Alcohol-Associated Liver Disease

Journal of Clinical and Experimental Hepatology
2022-11 | Journal article
DOI: 10.1016/j.jceh.2022.05.004
Contributors: Natalia A. Osna; Karuna Rasineni; Murali Ganesan; Terrence M. Donohue, Jr.; Kusum K. Kharbanda
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Alcohol and HIV-Derived Hepatocyte Apoptotic Bodies Induce Hepatic Stellate Cell Activation

Biology
2022-07-14 | Journal article
DOI: 10.3390/biology11071059
Contributors: Moses New-Aaron; Raghubendra Singh Dagur; Siva Sankar Koganti; Murali Ganesan; Weimin Wang; Edward Makarov; Mojisola Ogunnaike; Kusum K. Kharbanda; Larisa Y. Poluektova; Natalia A. Osna
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Malondialdehyde-Acetaldehyde Adduct Formation Decreases Immunoglobulin A Transport across Airway Epithelium in Smokers Who Abuse Alcohol

The American Journal of Pathology
2021-10 | Journal article
DOI: 10.1016/j.ajpath.2021.06.007
Contributors: Todd A. Wyatt; Kristi J. Warren; Tanner J. Wetzel; Troy Suwondo; Gage P. Rensch; Jane M. DeVasure; Deanna D. Mosley; Kusum K. Kharbanda; Geoffrey M. Thiele; Ellen L. Burnham et al.
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Alcohol-Induced Lysosomal Damage and Suppression of Lysosome Biogenesis Contribute to Hepatotoxicity in HIV-Exposed Liver Cells

Biomolecules
2021-10-11 | Journal article
DOI: 10.3390/biom11101497
Contributors: Moses New-Aaron; Paul G. Thomes; Murali Ganesan; Raghubendra Singh Dagur; Terrence M. Donohue, Jr.; Kharbanda K. Kusum; Larisa Y. Poluektova; Natalia A. Osna
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Beneficial Effects of Betaine: A Comprehensive Review

Biology
2021-05-22 | Journal article
DOI: 10.3390/biology10060456
Contributors: Madan Kumar Arumugam; Matthew C. Paal; Terrence M. Donohue, Jr.; Murali Ganesan; Natalia A. Osna; Kusum K. Kharbanda
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Pancreatogenic Diabetes: Triggering Effects of Alcohol and HIV

Biology
2021-02-03 | Journal article
DOI: 10.3390/biology10020108
Contributors: Moses New-Aaron; Murali Ganesan; Raghubendra Singh Dagur; Kusum K. Kharbanda; Larisa Y. Poluektova; Natalia A. Osna
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Alcohol-and-HIV-Induced Lysosomal Dysfunction Regulates Extracellular Vesicles Secretion in Vitro and in Liver-Humanized Mice

Biology
2021-01-05 | Journal article
DOI: 10.3390/biology10010029
Contributors: Raghubendra Singh Dagur; Moses New-Aaron; Murali Ganesan; Weimin Wang; Svetlana Romanova; Srivatsan Kidambi; Kusum K. Kharbanda; Larisa Y. Poluektova; Natalia A. Osna
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Second hits exacerbate alcohol-related organ damage: an update

Alcohol and Alcoholism
2021-01-04 | Journal article
DOI: 10.1093/alcalc/agaa085
Contributors: Natalia A Osna; Murali Ganesan; Devanshi Seth; Todd A Wyatt; Srivatsan Kidambi; Kusum K Kharbanda
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Susceptibility of Asialoglycoprotein Receptor-Deficient Mice to LPS/Galactosamine Liver Injury and Protection by Betaine Administration

Biology
2020-12-31 | Journal article
DOI: 10.3390/biology10010019
Contributors: Karuna Rasineni; Serene M. L. Lee; Benita L. McVicker; Natalia A. Osna; Carol A. Casey; Kusum K. Kharbanda
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Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease

Cells
2020-06-23 | Journal article
DOI: 10.3390/cells9061526
Contributors: Madan Kumar Arumugam; Sharanappa Talawar; Laura Listenberger; Terrence M. Donohue, Jr.; Natalia A. Osna; Kusum K. Kharbanda
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Recent Advances in Understanding the Complexity of Alcohol-Induced Pancreatic Dysfunction and Pancreatitis Development

Biomolecules
2020-04 | Journal article | Author
DOI: 10.3390/biom10050669
Contributors: Karuna Rasineni; Mukund P. Srinivasan; Appakalai N. Balamurugan; Bhupendra S. Kaphalia; Shaogui Wang; Wen-Xing Ding; Stephen J. Pandol; Aurelia Lugea; Liz Simon; Patricia E. Molina et al.
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Multidisciplinary Digital Publishing Institute

Alcohol Metabolism Potentiates HIV-Induced Hepatotoxicity: Contribution to End-Stage Liver Disease

Biomolecules
2019-12-10 | Journal article
DOI: 10.3390/biom9120851
Contributors: Murali Ganesan; Moses New-Aaron; Raghubendra Singh Dagur; Edward Makarov; Weimin Wang; Kusum K. Kharbanda; Srivatsan Kidambi; Larisa Y. Poluektova; Natalia A. Osna
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Inhibition of Ghrelin Activity by Receptor Antagonist [d-Lys-3] GHRP-6 Attenuates Alcohol-Induced Hepatic Steatosis by Regulating Hepatic Lipid Metabolism

Biomolecules
2019-09-21 | Journal article
DOI: 10.3390/biom9100517
Contributors: Karuna Rasineni; Jacy L. Kubik; Carol A. Casey; Kusum K. Kharbanda
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Decreasing Phosphatidylcholine on the Surface of the Lipid Droplet Correlates with Altered Protein Binding and Steatosis

Cells
2018-11 | Journal article | Author
DOI: 10.3390/cells7120230
Contributors: Laura Listenberger; Elizabeth Townsend; Cassandra Rickertsen; Anastasia Hains; Elizabeth Brown; Emily G. Inwards; Angela K. Stoeckman; Mitchell P. Matis; Rebecca S. Sampathkumar; Natalia Osna et al.
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Multidisciplinary Digital Publishing Institute

Hepatitis C Virus-Infected Apoptotic Hepatocytes Program Macrophages and Hepatic Stellate Cells for Liver Inflammation and Fibrosis Development: Role of Ethanol as a Second Hit

Biomolecules
2018-10 | Journal article | Author
DOI: 10.3390/biom8040113
Contributors: Murali Ganesan; Larisa Poluektova; Chijioke Enweluzo; Kusum Kharbanda; Natalia Osna
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Multidisciplinary Digital Publishing Institute
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The Loss of α- and β-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing

Brain Sciences
2018-09 | Journal article | Author
DOI: 10.3390/brainsci8090175
Contributors: Wajana L. Labisso; Ana-Caroline Raulin; Lucky Legbosi Nwidu; Artur Kocon; Declan Wayne; Amaia M. Erdozain; Benito Morentin; Daniela Schwendener; George Allen; Jack Enticott et al.
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Multidisciplinary Digital Publishing Institute

Role of Nutrition in Alcoholic Liver Disease: <em>Summary of the Symposium at the ESBRA 2017 Congress</em>

Biomolecules
2018-03 | Journal article
DOI: 10.3390/biom8020016
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Multidisciplinary Digital Publishing Institute
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Demethylase JMJD6 as a New Regulator of Interferon Signaling: Effects of HCV and Ethanol Metabolism

Cellular and Molecular Gastroenterology and Hepatology
2017-10 | Journal article
DOI: 10.1016/j.jcmgh.2017.10.004
Contributors: Murali Ganesan; Irina Tikhanovich; Shiva Shankar Vangimalla; Raghubendra Singh Dagur; Weimin Wang; Larisa I. Poluektova; Yimin Sun; David F. Mercer; Dean Tuma; Steven A. Weinman et al.
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Bifunctional Enzyme JMJD6 Contributes to Multiple Disease Pathogenesis: New Twist on the Old Story

Biomolecules
2017-06 | Journal article
DOI: 10.3390/biom7020041
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Multidisciplinary Digital Publishing Institute
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Multi-Organ Alcohol-Related Damage: Mechanisms and Treatment

Biomolecules
2016-04 | Journal article
DOI: 10.3390/biom6020020
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Multidisciplinary Digital Publishing Institute
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Hepatitis C, Innate Immunity and Alcohol: Friends or Foes?

Biomolecules
2015-02-05 | Journal article
DOI: 10.3390/biom5010076
Contributors: Natalia Osna; Murali Ganesan; Kusum Kharbanda
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Ethanol affects hepatitis C pathogenesis: Humanized SCID Alb-uPA mouse model

Biochemical and Biophysical Research Communications
2014-07 | Journal article
DOI: 10.1016/j.bbrc.2014.06.048
Contributors: Natalia A. Osna; Kusum K. Kharbanda; Yimin Sun; Ronda L. Simpson; Larisa E. Poluektova; Murali Ganesan; James L. Wisecarver; David F. Mercer
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Characterization of Timed Changes in Hepatic Copper Concentrations, Methionine Metabolism, Gene Expression, and Global DNA Methylation in the Jackson Toxic Milk Mouse Model of Wilson Disease

International Journal of Molecular Sciences
2014-05-07 | Journal article
DOI: 10.3390/ijms15058004
Contributors: Anh Le; Noreene Shibata; Samuel French; Kyoungmi Kim; Kusum Kharbanda; Mohammad Islam; Janine LaSalle; Charles Halsted; Carl Keen; Valentina Medici
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Peer review (2 reviews for 1 publication/grant)

Review activity for European journal of nutrition. (2)
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