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Employment (2)

Shionogi & Co., Ltd. (Japan): Osaka, JP

2011-10-11 to present | Director, Infectious Diseases (Laboratory for Drug Discovery and Disease Research)
Employment
Source: Self-asserted source
Teruhisa KATO

Nagasaki University: Nagasaki, JP

2019-04-01 to 2022-09-30 | Visiting Associate Professor (Institute of Tropical Medicine (NEKKEN), SHINE)
Employment
Source: Self-asserted source
Teruhisa KATO

Education and qualifications (1)

Fukui Prefectural University: Yoshida-gun, JP

1998-04-01 to 2001-03-31 (Bioscience and Biotechnology)
Qualification
Source: Self-asserted source
Teruhisa KATO

Works (19)

Oral 3CL protease inhibitor ensitrelvir suppressed SARS-CoV-2 shedding and infection in a hamster aerosol transmission model

Antiviral Research
2024-12 | Journal article
DOI: 10.1016/j.antiviral.2024.106026
Contributors: Masaaki Nakashima; Haruaki Nobori; Takayuki Kuroda; Alice Shimba; Satoshi Miyagawa; Akane Hayashi; Kazumi Matsumoto; Mei Yoshida; Kaoru Baba; Teruhisa Kato et al.
Source: check_circle
Crossref

Accelerating Antimalarial Drug Discovery with a New High-Throughput Screen for Fast-Killing Compounds

ACS Infectious Diseases
2024-12-13 | Journal article
DOI: 10.1021/acsinfecdis.4c00328
Contributors: Takaya Sakura; Ryuta Ishii; Eri Yoshida; Kiyoshi Kita; Teruhisa Kato; Daniel Ken Inaoka
Source: check_circle
Crossref

Prophylactic effect of ensitrelvir in mice infected with SARS-CoV-2

Antiviral Research
2024-04 | Journal article
DOI: 10.1016/j.antiviral.2024.105852
Contributors: Haruaki Nobori; Keiko Baba; Takayuki Kuroda; Kaoru Baba; Kazumi Matsumoto; Shinpei Yoshida; Ryosuke Watari; Yuki Tachibana; Teruhisa Kato; Keita Fukao
Source: check_circle
Crossref

Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of β-Herpesvirus Proteases

ACS Medicinal Chemistry Letters
2023-11-09 | Journal article
DOI: 10.1021/acsmedchemlett.3c00359
Contributors: Shuhei Yoshida; Yusuke Sako; Eiji Nikaido; Taichi Ueda; Iori Kozono; Yusuke Ichihashi; Atsufumi Nakahashi; Motoyasu Onishi; Yukiko Yamatsu; Teruhisa Kato et al.
Source: check_circle
Crossref

Pharmacokinetic and Pharmacodynamic Analysis of the 3CL Protease Inhibitor Ensitrelvir in a SARS-CoV-2 Infection Mouse Model

Viruses
2023-10-05 | Journal article
DOI: 10.3390/v15102052
Contributors: Keita Fukao; Haruaki Nobori; Takayuki Kuroda; Kaoru Baba; Kazumi Matsumoto; Yukari Tanaka; Yuki Tachibana; Teruhisa Kato; Takao Shishido
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Ensitrelvir is effective against SARS-CoV-2 3CL protease mutants circulating globally

Biochemical and Biophysical Research Communications
2023-02 | Journal article
DOI: 10.1016/j.bbrc.2023.01.040
Contributors: Sho Kawashima; Yuki Matsui; Takumi Adachi; Yuji Morikawa; Kae Inoue; Shiori Takebayashi; Haruaki Nobori; Masatomo Rokushima; Yuki Tachibana; Teruhisa Kato
Source: check_circle
Crossref

Efficacy comparison of 3CL protease inhibitors ensitrelvir and nirmatrelvir against SARS-CoV-2 in vitro and in vivo

2023-01-26 | Other
DOI: 10.1093/jac/dkad027
Contributors: Takayuki Kuroda; Yuki Tachibana; Teruhisa Kato; Haruaki Nobori; Keita Fukao; Shinpei Yoshida; Yukari Tanaka; Ryosuke Watari; Yasuyuki Kasai; Kae Inoue et al.
Source: check_circle
Crossref

S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters

Science Translational Medicine
2022-11-03 | Journal article | Author
DOI: 10.1126/scitranslmed.abq4064
Part of ISSN: 1946-6234
Part of ISSN: 1946-6242
Contributors: Michihito Sasaki; Koshiro Tabata; Mai Kishimoto; Yukari Itakura; Hiroko Kobayashi; Takuma Ariizumi; Kentaro Uemura; Shinsuke Toba; Shinji Kusakabe; Yuki MARUYAMA et al.
Source: Self-asserted source
Teruhisa KATO

Efficacy of ensitrelvir against SARS-CoV-2 in a delayed-treatment mouse model

Journal of Antimicrobial Chemotherapy
2022-08-01 | Journal article
DOI: 10.1093/jac/dkac257
Part of ISSN: 0305-7453
Part of ISSN: 1460-2091
Contributors: Teruhisa KATO
Source: Self-asserted source
Teruhisa KATO

Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

Journal of Medicinal Chemistry
2022-05-12 | Journal article
DOI: 10.1021/acs.jmedchem.2c00117
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Teruhisa KATO

Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel

Bioorganic & Medicinal Chemistry Letters
2011-08 | Journal article
DOI: 10.1016/j.bmcl.2011.06.035
Part of ISSN: 0960-894X
Source: Self-asserted source
Teruhisa KATO

N-(2-Hydroxyethyl)-N,2-dimethyl-8-{[(4R)-5-methyl-3,4-dihydro-2H-chromen-4-yl]amino}imidazo[1,2-a]pyridine-6-carboxamide (PF-03716556), a Novel, Potent, and Selective Acid Pump Antagonist for the Treatment of Gastroesophageal Reflux Disease

Journal of Pharmacology and Experimental Therapeutics
2009-02 | Journal article
DOI: 10.1124/jpet.108.146415
Part of ISSN: 0022-3565
Part of ISSN: 1521-0103
Source: Self-asserted source
Teruhisa KATO

Aryl Hydrocarbon Receptor and Estrogen Receptor Ligand Activity of Organic Extracts from Road Dust and Diesel Exhaust Particulates

Archives of Environmental Contamination and Toxicology
2008-08 | Journal article
DOI: 10.1007/s00244-007-9110-5
Part of ISSN: 0090-4341
Part of ISSN: 1432-0703
Source: Self-asserted source
Teruhisa KATO

High throughput solubility measurement with automated polarized light microscopy analysis

Journal of Pharmaceutical Sciences
2006-10 | Journal article
DOI: 10.1002/jps.20628
Part of ISSN: 0022-3549
Source: Self-asserted source
Teruhisa KATO

Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis

Life Sciences
2005-02 | Journal article
DOI: 10.1016/j.lfs.2004.08.030
Part of ISSN: 0024-3205
Source: Self-asserted source
Teruhisa KATO

Estrogenic and Anti-Androgenic Activities of Benzophenones in Human Estrogen and Androgen Receptor Mediated Mammalian Reporter Gene Assays

Journal of Health Science
2005-02 | Journal article
DOI: 10.1248/jhs.51.48
Part of ISSN: 1344-9702
Part of ISSN: 1347-5207
Source: Self-asserted source
Teruhisa KATO

Molecular Cloning and Characterization of a cDNA for a Rice Sec31p Homolog

Bioscience, Biotechnology, and Biochemistry
2000-01-01 | Journal article
DOI: 10.1271/bbb.64.2490
Part of ISSN: 0916-8451
Part of ISSN: 1347-6947
Source: Self-asserted source
Teruhisa KATO

Suppression of the heterotrimeric G protein causes abnormal morphology, including dwarfism, in rice

Proceedings of the National Academy of Sciences
1999-06-22 | Journal article
DOI: 10.1073/pnas.96.13.7575
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Teruhisa KATO

Characterization of the putative alpha subunit of a heterotrimeric G protein in rice

Plant Molecular Biology
1997-07 | Journal article
DOI: 10.1023/a:1005807010811
Part of ISSN: 0167-4412
Source: Self-asserted source
Teruhisa KATO
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