Personal information

Other IDs

ResearcherID: I-1941-2013
Scopus Author ID: 55813124900

Keywords

Mitochondrial Physiology, Insulin Resistance

Countries

Australia

Biography

Postdoctoral researcher
Interested in insulin resistance and mitochondrial physiology

Activities

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Works (39)

Erratum: Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet (iScience (2021) 24(10), (S2589004221010671), (10.1016/j.isci.2021.103099))

iScience
2024 | Journal article
DOI: 10.1016/j.isci.2023.108707
EID:

2-s2.0-85180457254

Part of ISSN: 25890042
Contributors: Yau, B.; Naghiloo, S.; Diaz-Vegas, A.; Carr, A.V.; Van Gerwen, J.; Needham, E.J.; Jevon, D.; Chen, S.-Y.; Hoehn, K.L.; Brandon, A.E. et al.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

The genetic and dietary landscape of the muscle insulin signalling network

eLife
2024 | Journal article
DOI: 10.7554/eLife.89212
EID:

2-s2.0-85184728333

Part of ISSN: 2050084X
Contributors: van Gerwen, J.; Masson, S.W.C.; Cutler, H.B.; Vegas, A.D.; Potter, M.; Stöckli, J.; Madsen, S.; Nelson, M.E.; Humphrey, S.J.; James, D.E.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Deletion of miPEP in adipocytes protects against obesity and insulin resistance by boosting muscle metabolism

Molecular Metabolism
2024-08 | Journal article
DOI: 10.1016/j.molmet.2024.101983
Contributors: Alexis Diaz-Vegas; Kristen C. Cooke; Harry B. Cutler; Belinda Yau; Stewart W.C. Masson; Dylan Harney; Oliver K. Fuller; Meg Potter; Søren Madsen; Niamh R. Craw et al.
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Crossref

Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy

eLife
2023 | Journal article
DOI: 10.7554/eLife.82619
EID:

2-s2.0-85160974569

Part of ISSN: 2050084X
Contributors: Krishnan, K.C.; El Hachem, E.-J.; Keller, M.P.; Patel, S.G.; Carroll, L.; Vegas, A.D.; Gyuricza, I.G.; Light, C.; Cao, Y.; Pan, C. et al.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

eLife
2023 | Journal article
DOI: 10.7554/eLife.86961
EID:

2-s2.0-85165669513

Part of ISSN: 2050084X
Contributors: Masson, S.W.C.; Madsen, S.; Cooke, K.C.; Potter, M.; Vegas, A.D.; Carroll, L.; Thillainadesan, S.; Cutler, H.B.; Walder, K.R.; Cooney, G.J. et al.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

The genetic and dietary landscape of the muscle insulin signalling network

bioRxiv
2023 | Other
DOI: 10.1101/2023.06.21.546001
EID:

2-s2.0-85165934624

Part of ISSN: 26928205
Contributors: van Gerwen, J.; Masson, S.W.C.; Cutler, H.B.; Díaz-Vegas, A.; Potter, M.; Stöckli, J.; Madsen, S.; Nelson, M.E.; Humphrey, S.J.; James, D.E.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle

eLife
2023-12-27 | Journal article
DOI: 10.7554/eLife.87340.3
Contributors: Alexis Diaz-Vegas; Søren Madsen; Kristen C Cooke; Luke Carroll; Jasmine XY Khor; Nigel Turner; Xin Y Lim; Miro A Astore; Jonathan C Morris; Anthony S Don et al.
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Crossref

Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle

eLife
2023-12-27 | Journal article
DOI: 10.7554/eLife.87340
Contributors: Alexis Diaz-Vegas; Søren Madsen; Kristen C Cooke; Luke Carroll; Jasmine XY Khor; Nigel Turner; Xin Y Lim; Miro A Astore; Jonathan C Morris; Anthony S Don et al.
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Deep Proteome Profiling of White Adipose Tissue Reveals Marked Conservation and Distinct Features Between Different Anatomical Depots

Molecular & Cellular Proteomics
2023-03 | Journal article
DOI: 10.1016/j.mcpro.2023.100508
Part of ISSN: 1535-9476
Contributors: Søren Madsen; Marin E. Nelson; Vinita Deshpande; Sean J. Humphrey; Kristen C. Cooke; Anna Howell; Alexis Diaz-Vegas; James G. Burchfield; Jacqueline Stöckli; David E. James
Source: Self-asserted source
Díaz-Vegas A
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Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle

2023-03-12 | Preprint
DOI: 10.1101/2023.03.10.532020
Contributors: Alexis Diaz-Vegas; Soren Madsen; Kristen C. Cooke; Luke Carroll; Jasmine X.Y. Khor; Nigel Turner; Xin Ying Lim; Miro Astore; Jonathan Morris; Anthony Don et al.
Source: Self-asserted source
Díaz-Vegas A
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Leveraging genetic diversity to identify small molecules that reverse mouse skeletal muscle insulin resistance

2023-03-03 | Preprint
DOI: 10.1101/2023.03.01.530673
Contributors: Stewart W.C. Masson; Søren Madsen; Kristen C. Cooke; Meg Potter; Alexis Diaz-Vegas; Luke Carroll; Senthil Thillainadesan; Ken Walder; Gregory J. Cooney; Grant Morahan et al.
Source: Self-asserted source
Díaz-Vegas A
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Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance

Nature Communications
2023-02-18 | Journal article
DOI: 10.1038/s41467-023-36549-2
Part of ISSN: 2041-1723
Contributors: Daniel Fazakerley; Julian van Gerwen; Kristen C. Cooke; Xiaowen Duan; Elise J. Needham; Alexis Díaz-Vegas; Søren Madsen; Dougall M. Norris; Amber Shun-Shion; James R. Krycer et al.
Source: Self-asserted source
Díaz-Vegas A
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A high-content endogenous GLUT4 trafficking assay reveals new aspects of adipocyte biology

Life Science Alliance
2023-01 | Journal article
DOI: 10.26508/lsa.202201585
Contributors: Alexis Diaz-Vegas; Dougall M Norris; Sigrid Jall-Rogg; Kristen C Cooke; Olivia J Conway; Amber S Shun-Shion; Xiaowen Duan; Meg Potter; Julian van Gerwen; Harry JM Baird et al.
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Deep proteome profiling of white adipose tissue reveals marked conservation and distinct features between different anatomical depots

bioRxiv
2022 | Other
DOI: 10.1101/2022.08.23.504892
EID:

2-s2.0-85142851126

Part of ISSN: 26928205
Contributors: Madsen, S.; Nelson, M.E.; Deshpande, V.; Humphrey, S.J.; Cooke, K.C.; Howell, A.; Diaz-Vegas, A.; Burchfield, J.G.; Stöckli, J.; James, D.E.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy

2022-08-26 | Preprint
DOI: 10.1101/2022.08.24.505177
Contributors: Karthickeyan Chella Krishnan; Elie-Julien El Hachem; Luke Carroll; Alexis Diaz Vegas; Christine Light; Yang Cao; Calvin Pan; Karolina Elżbieta Kaczor-Urbanowicz; Varun Shravah; Diana Anum et al.
Source: Self-asserted source
Díaz-Vegas A

Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet

iScience
2021-10 | Journal article
DOI: 10.1016/j.isci.2021.103099
Part of ISSN: 2589-0042
Contributors: Belinda Yau; Sheyda Naghiloo; Alexis Diaz-Vegas; Austin V. Carr; Julian van Gerwen; Elise Needham; Dillon Jevon; Sing-Young Chen; Kyle L. Hoehn; Amanda E. Brandon et al.
Source: Self-asserted source
Díaz-Vegas A
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Dissecting the biology of mTORC1 beyond rapamycin

Science Signaling
2021-09-21 | Journal article
DOI: 10.1126/scisignal.abe0161
Contributors: Guang Yang; Deanne Francis; James R. Krycer; Mark Larance; Ziyang Zhang; Chris J. Novotny; Alexis Diaz-Vegas; Kevan M. Shokat; David E. James
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Endoplasmic reticulum−mitochondria coupling increases during doxycycline-induced mitochondrial stress in HeLa cells

Cell Death & Disease
2021-06-28 | Journal article
DOI: 10.1038/s41419-021-03945-9
Contributors: Camila Lopez-Crisosto; Alexis Díaz-Vegas; Pablo F. Castro; Beverly A. Rothermel; Roberto Bravo-Sagua; Sergio Lavandero
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Changes in Gene Expression of the MCU Complex Are Induced by Electrical Stimulation in Adult Skeletal Muscle

Frontiers in Physiology
2021-01-26 | Journal article
DOI: 10.3389/fphys.2020.601313
Part of ISSN: 1664-042X
Contributors: Esteban R. Quezada; Alexis Díaz-Vegas; Enrique Jaimovich; Mariana Casas
Source: Self-asserted source
Díaz-Vegas A
grade
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Fibroblast growth factor-21 potentiates glucose transport in skeletal muscle fibers

Journal of Molecular Endocrinology
2020-10 | Journal article
DOI: 10.1530/jme-19-0210
Part of ISSN: 0952-5041
Part of ISSN: 1479-6813
Contributors: G Rosales-Soto; A Diaz-Vegas; M Casas; A Contreras-Ferrat; E Jaimovich
Source: Self-asserted source
Díaz-Vegas A
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Insulin signaling requires glucose to promote lipid anabolism in adipocytes

Journal of Biological Chemistry
2020-09 | Journal article
DOI: 10.1074/jbc.RA120.014907
Contributors: James R. Krycer; Lake-Ee Quek; Deanne Francis; Armella Zadoorian; Fiona C. Weiss; Kristen C. Cooke; Marin E. Nelson; Alexis Diaz-Vegas; Sean J. Humphrey; Richard Scalzo et al.
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Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?

Endocrine Reviews
2020-06-01 | Journal article
DOI: 10.1210/endrev/bnaa005
Part of ISSN: 0163-769X
Part of ISSN: 1945-7189
Contributors: Alexis Diaz-Vegas; Pablo Sanchez-Aguilera; James R Krycer; Pablo E Morales; Matías Monsalves-Alvarez; Mariana Cifuentes; Beverly A Rothermel; Sergio Lavandero
Source: Self-asserted source
Díaz-Vegas A
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Effect of thermally reduced graphene oxides obtained at different temperatures on the barrier and mechanical properties of polypropylene/TRGO and polyamide-6/TRGO nanocomposites

Polymer Composites
2019 | Journal article
DOI: 10.1002/pc.25143
EID:

2-s2.0-85055976998

Part of ISSN: 15480569 02728397
Contributors: Gómez, M.; Díaz, A.; Reyes, P.; Yazdani-Pedram, M.; Bohrz Nachtigall, S.M.; Palza, H.; Quijada, R.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Fibroblast growth factor 21 promotes glucose uptake by a glut4-dependent and akt-independent mechanism in isolated fibers of skeletal muscle

Revista Cubana de Investigaciones Biomedicas
2019 | Journal article
EID:

2-s2.0-85079129516

Part of ISSN: 15613011 08640300
Contributors: Rosales-Soto, G.; Díaz-Vegas, A.; Llanos, P.; Casas, M.; Jaimovich, E.; Contreras-Ferrat, A.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes.

The Journal of biological chemistry
2019-11-19 | Journal article
DOI: 10.1074/jbc.ra119.011695
PMID: 31744882
Source: Self-asserted source
Díaz-Vegas A
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Lactate production is a prioritised feature of adipocyte metabolism.

The Journal of biological chemistry
2019-11-05 | Journal article
DOI: 10.1074/jbc.ra119.011178
PMID: 31690627
Source: Self-asserted source
Díaz-Vegas A
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GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication.

Pharmacological research
2019-05-13 | Journal article
DOI: 10.1016/j.phrs.2019.104273
PMID: 31096010
Source: Self-asserted source
Díaz-Vegas A
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Skeletal muscle excitation-metabolism coupling.

Archives of biochemistry and biophysics
2019-02-01 | Journal article
DOI: 10.1016/j.abb.2019.01.037
PMID: 30716283
Source: Self-asserted source
Díaz-Vegas A
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Eccentric resistance training reduces both non-response to exercise and cardiovascular risk factors in adult with overweight or obesity,L'entraînement excentrique en force réduit les facteurs de risque cardiovasculaire d'adultes en surpoids ou obèses avec une moindre fréquence de non-réponses

Science and Sports
2018 | Journal article
DOI: 10.1016/j.scispo.2017.12.002
EID:

2-s2.0-85042912748

Part of ISSN: 17784131 07651597
Contributors: Díaz-Vegas, A.; Espinoza, A.; Cofré, C.; Sánchez-Aguilera, P.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Excitation-Metabolism Coupling in Skeletal Muscle: Ca²-Dependent O₂ Consumption and Spreading of Mitochondria Membrane Potential

SSRN
2018 | Other
DOI: 10.2139/ssrn.3155798
EID:

2-s2.0-85115527821

Part of ISSN: 15565068
Contributors: Díaz-Vegas, A.; Cordova, A.; Valladares, D.; Llanos, P.; Hidalgo, C.; Gherardi, G.; de Stefani, D.; Mammucari, C.; Rizzuto, R.; Contreras-Ferrat, A. et al.
Source: Self-asserted source
Díaz-Vegas A via Scopus - Elsevier

Role of ABCA1 on membrane cholesterol content, insulin-dependent Akt phosphorylation and glucose uptake in adult skeletal muscle fibers from mice.

Biochimica et biophysica acta. Molecular and cell biology of lipids
2018-09-19 | Journal article
DOI: 10.1016/j.bbalip.2018.09.005
PMID: 30254016
Source: Self-asserted source
Díaz-Vegas A
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IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice.

Biochimica et biophysica acta. Molecular basis of disease
2018-09-07 | Journal article
DOI: 10.1016/j.bbadis.2018.08.042
PMID: 30251688
Source: Self-asserted source
Díaz-Vegas A
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Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism.

Frontiers in physiology
2018-06-25 | Journal article
DOI: 10.3389/fphys.2018.00791
PMID: 29988564
PMC: PMC6026899
Source: Self-asserted source
Díaz-Vegas A
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Potential adverse cardiac remodelling in highly trained athletes: still unknown clinical significance.

European journal of sport science
2018-06-12 | Journal article
DOI: 10.1080/17461391.2018.1484174
PMID: 29893180
Source: Self-asserted source
Díaz-Vegas A
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Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?

Free radical biology & medicine
2018-05-30 | Journal article
DOI: 10.1016/j.freeradbiomed.2018.05.084
PMID: 29859344
Source: Self-asserted source
Díaz-Vegas A
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NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout.

Frontiers in physiology
2016-07-14 | Journal article
DOI: 10.3389/fphys.2016.00282
PMID: 27471471
PMC: PMC4944119
Source: Self-asserted source
Díaz-Vegas A
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Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle.

Skeletal muscle
2016-04-11 | Journal article
DOI: 10.1186/s13395-016-0087-5
PMID: 27069569
PMC: PMC4827232
Source: Self-asserted source
Díaz-Vegas A
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ROS Production via P2Y1-PKC-NOX2 Is Triggered by Extracellular ATP after Electrical Stimulation of Skeletal Muscle Cells.

PloS one
2015-06-08 | Journal article
DOI: 10.1371/journal.pone.0129882
PMID: 26053483
PMC: PMC4460042
Source: Self-asserted source
Díaz-Vegas A
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Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet.

2013 | Journal article
DOI:

10.3390/ijms140815740

PMID:

23899788
Contributors: Bucarey JL; Campos C; Contreras-Ferrat A; Díaz-Vegas A; Espinosa A; Galgani JE; Jaimovich E; Juretic N; Llanos P; Osorio-Fuentealba C et al.
Source: Self-asserted source
Díaz-Vegas A via Europe PubMed Central
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