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Karolinska University Hospital: Stockholm, SE

(Astrid Lindgren Children's Hospital)
Employment
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Karolinska Institutet

Karolinska Institutet: Stockholm, SE

(Department of Women's and Children's Health)
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Karolinska Institutet

Education and qualifications (1)

Karolinska Institutet: Stockholm, SE

1991-06-14 to present | MD
Education
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Anna Nilsson

Works (50 of 79)

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A distinct alternative mRNA splicing profile identifies the oncogenic CD44 transcript variant 3 in KMT2A-rearranged pediatric T-cell acute lymphoblastic leukemia cells

Experimental Hematology
2025-01 | Journal article
DOI: 10.1016/j.exphem.2025.104712
Contributors: Amanda Ramilo Amor; Sabina Enlund; Indranil Sinha; Qingfei Jiang; Ola Hermanson; Anna Nilsson; Shahrzad Shirazi Fard; Frida Holm
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Crossref

A Distinct Alternative mRNA Splicing Profile Identifies the Oncogenic CD44 Transcript Variant 3 in KMT2A-Rearranged Pediatric T-cell Acute Lymphoblastic Leukemia Cells

2024-09-06 | Preprint
DOI: 10.1101/2024.09.05.611385
Contributors: Amanda Ramilo Amor; Sabina Enlund; Indranil Sinha; Qingfei Jiang; Ola Hermanson; Anna Nilsson; Shahrzad Shirazi Fard; Frida Holm
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Crossref

Bone Marrow-Suppressive Treatment in Children Is Associated with Diminished IFN-γ Response from T Cells upon Polyclonal and Varicella Zoster Virus Peptide Stimulation

International Journal of Molecular Sciences
2024-06-26 | Journal article
DOI: 10.3390/ijms25136960
Contributors: Eva Tiselius; Emil Sundberg; Hanna Andersson; Anna Höbinger; Peter Jahnmatz; Arja Harila; Josefine Palle; Anna Nilsson; Shanie Saghafian-Hedengren
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The CNS microenvironment promotes leukemia cell survival by disrupting tumor suppression and cell cycle regulation in pediatric T-cell acute lymphoblastic leukemia

Experimental Cell Research
2024-04 | Journal article
DOI: 10.1016/j.yexcr.2024.114015
Contributors: Sabina Enlund; Indranil Sinha; Christina Neofytou; Amanda Ramilo Amor; Konstantinos Papadakis; Anna Nilsson; Qingfei Jiang; Ola Hermanson; Frida Holm
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Crossref

The CNS Microenvironment Promotes Leukemia Cell Survival by Disrupting Tumor Suppression and Cell Cycle Regulation in Pediatric T-cell Acute Lymphoblastic Leukemia

2023-09-05 | Preprint
DOI: 10.1101/2023.09.01.555887
Contributors: Sabina Enlund; Indranil Sinha; Christina Neofytou; Amanda Ramilo Amor; Konstantinos Papadakis; Anna Nilsson; Qingfei Jiang; Ola Hermanson; Frida Holm
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Crossref

The Applicability of a 2-Transcript Signature to Identify Bacterial Infections in Children with Febrile Neutropenia

Children
2023-05-29 | Journal article
DOI: 10.3390/children10060966
Contributors: Johannes Aasa; Eva Tiselius; Indranil Sinha; Gunnar Edman; Martina Wahlund; Shanie Saghafian Hedengren; Anna Nilsson; Anna Berggren
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Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T‐cell acute lymphoblastic leukemia

eJHaem
2023-02 | Journal article
DOI: 10.1002/jha2.634
Contributors: Sabina Enlund; Indranil Sinha; Amanda Ramilo Amor; Shahrzad Shirazi Fard; Ekaterina Pokrovskaja Tamm; Qingfei Jiang; Vanessa Lundin; Anna Nilsson; Frida Holm
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Crossref

Four-Parameter FluoroSpot Assay Reveals That the Varicella Zoster Virus Elicits a Robust Memory T Cell IL-10 Response throughout Childhood

Journal of Virology
2022-11-23 | Journal article
DOI: 10.1128/jvi.01310-22
Contributors: Anna Nilsson; Anna Höbinger; Peter Jahnmatz; Eva Tiselius; Åsa Laestadius; Erik Melén; Sophia Björkander; Shanie Saghafian-Hedengren; Rebecca Ellis Dutch
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Crossref

COVID‐19 seroprevalence and clinical picture in Swedish pediatric oncology and hematology patients

Pediatric Blood & Cancer
2022-10 | Journal article
DOI: 10.1002/pbc.29773
Contributors: Emil Sundberg; Tove Hoffman; Anna Nilsson; Simon Pahnke; Gunilla Enblad; Linda Kolstad; Bengt Rönnberg; Åke Lundkvist; Milla Torkki; Otto Zhou et al.
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Crossref

Low numbers of COVID‐19 in Swedish pediatric oncology patients during the first pandemic year despite an open society

Pediatric Blood & Cancer
2022-10 | Journal article
DOI: 10.1002/pbc.29750
Contributors: Emil Sundberg; Kleopatra Georgantzi; Cecilia Langenskiöld; Ladislav Król; Frans Nilsson; Hartmut Vogt; Josefine Palle; Torben Ek; Anna Nilsson
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Crossref

T Cell Subsets During Early Life and Their Implication in the Treatment of Childhood Acute Lymphoblastic Leukemia

Front. Immunol.
2021 | Journal article
DOI: 10.3389/fimmu.2021.582539
SOURCE-WORK-ID:

146159246

PMID: 33763058
Contributors: Saghafian-Hedengren, S; Sverremark-Ekstrom, E; Nilsson, A
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Karolinska Institutet

Capillary blood sampling increases the risk of preanalytical errors in pediatric hospital care: Observational clinical study

Journal for Specialists in Pediatric Nursing
2021-10 | Journal article
DOI: 10.1111/jspn.12337
Contributors: Henrik Hjelmgren; Anna Nilsson; Ida H. Myrberg; Nina Andersson; Britt‐Marie Ygge; Björn Nordlund
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Crossref

Human Bone Marrow Mesenchymal Stromal Cell-Derived CXCL12, IL-6 and GDF-15 and Their Capacity to Support IgG-Secreting Cells in Culture Are Divergently Affected by Doxorubicin

Hemato
2021-03-13 | Journal article
DOI: 10.3390/hemato2010009
Contributors: Gintare Lasaviciute; Anna Höbinger; Dorina Ujvari; Daniel Salamon; Aisha Yusuf; Mikael Sundin; Eva Sverremark-Ekström; Rayan Chikhi; Anna Nilsson; Shanie Saghafian-Hedengren
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Deficits in the IgG(+) memory B-cell recovery after anthracycline treatment is confined to the spleen of rhesus macaques

Clin. Transl. Immunol.
2020 | Journal article
DOI: 10.1002/cti2.1150
SOURCE-WORK-ID:

144361586

PMID: 32642064
Contributors: Lasaviciute, G; Bricaud, AL; Hellgren, F; Ingelman-Sundberg, HM; Eksborg, S; Jonker, M; Haanstra, KG; Myrberg, IH; Sverremark-Ekstrom, E; Lore, K et al.
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Karolinska Institutet

Early Antiretroviral Therapy May Preserve Vaccine Responses in Human Immunodeficiency Virus-Infected Patients by Preventing Damage to Long-Lived Plasma Cells

J Infect Dis
2020 | Journal article
DOI: 10.1093/infdis/jiz679
SOURCE-WORK-ID:

144503182

PMID: 31867631
Contributors: Nilsson, A; Chiodi, F
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Karolinska Institutet

Extracorporeal Membrane Oxygenation Support in Children With Hematological Malignancies in Sweden

J Pediatr Hematol Oncol
2020 | Journal article
DOI: 10.1097/MPH.0000000000001808
SOURCE-WORK-ID:

232287104

PMID: 32287104
Contributors: Ranta, S; Kalzén, H; Nilsson, A; von Schewelov, K; Broman, LM; Berner, J; Fläring, U; Norén-Nyström, U; Svahn, JE; Palle, J et al.
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Karolinska Institutet

Fatal encephalitis associated with coronavirus OC43 in an immunocompromised child

Infect. Dis.
2020 | Journal article
DOI: 10.1080/23744235.2020.1729403
SOURCE-WORK-ID:

143013556

PMID: 32067542
Contributors: Nilsson, A; Edner, N; Albert, J; Ternhag, A
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Karolinska Institutet

The Feasibility of Host Transcriptome Profiling as a Diagnostic Tool for Microbial Etiology in Childhood Cancer Patients with Febrile Neutropenia

Int. J. Mol. Sci.
2020 | Journal article
DOI: 10.3390/ijms21155305
SOURCE-WORK-ID:

144415382

PMID: 32722616
Contributors: Wahlund, M; Sinha, I; Broliden, K; Saghafian-Hedengren, S; Nilsson, A; Berggren, A
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Karolinska Institutet

The Role of TPMT, ITPA, and NUDT15 Variants during Mercaptopurine Treatment of Swedish Pediatric Patients with Acute Lymphoblastic Leukemia

J. Pediatr.
2020 | Journal article
DOI: 10.1016/j.jpeds.2019.09.024
SOURCE-WORK-ID:

142524304

PMID: 31635813
Contributors: Wahlund, M; Nilsson, A; Kahlin, AZ; Broliden, K; Myrberg, IH; Appell, ML; Berggren, A
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Karolinska Institutet

Trends of Pediatric Bloodstream Infections in Stockholm, Sweden: A 20-year Retrospective Study

Pediatr. Infect. Dis. J.
2020 | Journal article
DOI: 10.1097/INF.0000000000002850
SOURCE-WORK-ID:

145098951

PMID: 32773664
Contributors: Luthander, J; Bennet, R; Giske, CG; Eriksson, M; Nilsson, A
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Karolinska Institutet

Validation of the new Swedish vaccination register - Accuracy and completeness of register data

Vaccine
2020 | Journal article
DOI: 10.1016/j.vaccine.2020.04.020
SOURCE-WORK-ID:

143703825

PMID: 32359874
Contributors: Chrapkowska, C; Galanis, I; Kark, M; Lepp, T; Lindstrand, A; Roth, A; Nilsson, A
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Karolinska Institutet

Genetic Sequence Variants in TLR4, MBL or IL-1 Receptor Antagonist is not Associated to Increased Risk for Febrile Neutropenia in Children with ALL

Children
2020-12-16 | Journal article
DOI: 10.3390/children7120296
Contributors: Martina Wahlund; Malin Lindqvist Appell; Ida Hed Myrberg; Anna Berggren; Anna Nilsson
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Peripheral facial nerve palsy in children in a Borrelia high‐endemic area, a retrospective follow‐up study

Acta Paediatrica
2020-06 | Journal article
DOI: 10.1111/apa.15063
Contributors: Sigurdur Arnason; Malou Hultcrantz; Anna Nilsson; Åsa Laestadius
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Antimicrobial Use in a Swedish Pediatric Hospital Results From Eight Point-prevalence Surveys Over a 15-Year Period (2003-2017)

Pediatr. Infect. Dis. J.
2019 | Journal article
DOI: 10.1097/INF.0000000000002393
SOURCE-WORK-ID:

141745291

PMID: 31220043
Contributors: Luthander, J; Bennet, R; Nilsson, A; Eriksson, M
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Karolinska Institutet

Clostridium difficile Infection in Children: Epidemiology and Trend in a Swedish Tertiary Care Hospital

Pediatr. Infect. Dis. J.
2019 | Journal article
DOI: 10.1097/INF.0000000000002480
SOURCE-WORK-ID:

142412557

PMID: 31738336
Contributors: Malmqvist, L; Ullberg, M; Myrberg, IH; Nilsson, A
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Karolinska Institutet

Urinary PGE2 metabolite levels in hospitalised infants with infections compared to age‐matched controls

Acta Paediatrica
2019-10 | Journal article
DOI: 10.1111/apa.14807
Contributors: Johan Hamrin; Monica Perez‐Manzo; Helena Idborg; Per‐Johan Jakobsson; Lars Björk; Margareta Eriksson; Anna Nilsson; Eric Herlenius
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Altered proportions of circulating CXCR5+ helper T cells do not dampen influenza vaccine responses in children with rheumatic disease

Vaccine
2019-06 | Journal article
DOI: 10.1016/j.vaccine.2019.05.037
Contributors: Åsa Laestadius; Hanna M. Ingelman-Sundberg; Ida Hed Myrberg; Anna Verme; Erik Sundberg; Brunhilde Schweiger; Shanie Saghafian-Hedengren; Anna Nilsson
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Homing defects of B cells in HIV-1 infected children impair vaccination responses

Vaccine
2019-04 | Journal article
DOI: 10.1016/j.vaccine.2019.03.027
Contributors: Yonas Bekele; Mahlet Lemma; Kidist Bobosha; Desalegn Yibeltal; Aikaterini Nasi; Meseret Gebre; Anna Nilsson; Abraham Aseffa; Rawleigh Howe; Francesca Chiodi
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Retrospective study showed that blood sampling errors risked children's well‐being and safety in a Swedish paediatric tertiary care

Acta Paediatrica
2019-03 | Journal article
DOI: 10.1111/apa.14528
Contributors: Henrik Hjelmgren; Anna Nilsson; Nina Andersson‐Papadogiannakis; Carina Ritzmo; Britt‐Marie Ygge; Björn Nordlund
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Early central line‐associated blood stream infections in children with cancer pose a risk for premature catheter removal

Acta Paediatrica
2019-02 | Journal article
DOI: 10.1111/apa.14432
Contributors: Jacob Moell; Anna Svenningsson; Margareta Af Sandeberg; Magnus Larsson; Mats Heyman; Arja Harila‐Saari; Anna Nilsson
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Insights into defective serological memory after acute lymphoblastic leukaemia treatment: The role of the plasma cell survival niche, memory B-cells and gut microbiota in vaccine responses

Blood Rev
2018 | Journal article
DOI: 10.1016/j.blre.2017.08.009
SOURCE-WORK-ID:

137814059

PMID: 28886882
Contributors: Saghafian-Hedengren, S; Söderström, I; Sverremark-Ekström, E; Nilsson, A
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Karolinska Institutet

What benefits do immunocompromised children get from the varicella zoster virus vaccination?

Acta Paediatrica
2018-12 | Journal article
DOI: 10.1111/apa.14591
Contributors: Anna Nilsson
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[The child immunisation programme--effective but insufficient. Experiences from the Astrid Lindgren pediatric hospital, 2008–2013]

Lakartidningen
2017 | Journal article
SOURCE-WORK-ID:

228094831

PMID: 28094831
Contributors: Laestadius, Å; Nilsson, A; Bennet, R; Bogdanovic, G; Eriksson, M
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Karolinska Institutet

Antibiotic use during infectious episodes in the first 6 months of anticancer treatment-A Swedish cohort study of children aged 7-16 years

Pediatr Blood Cancer
2017 | Journal article
DOI: 10.1002/pbc.26397
SOURCE-WORK-ID:

135951080

PMID: 28074531
Contributors: Af Sandeberg, M; Johansson, E; Wettergren, L; Björk, O; Hertting, O; Nilsson, A
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Karolinska Institutet

Assessment of Cytokine and Chemokine Signatures as Potential Biomarkers of Childhood Community-acquired Pneumonia Severity: A Nested Cohort Study in India

Pediatr Infect Dis J
2017 | Journal article
DOI: 10.1097/INF.0000000000001364
SOURCE-WORK-ID:

134962400

PMID: 27956727
Contributors: Saghafian-Hedengren, S; Mathew, JL; Hagel, E; Singhi, S; Ray, P; Ygberg, S; Nilsson, A
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Karolinska Institutet

Changing diagnosis coding routines may confound the results of longitudinal childhood pneumonia studies

Acta Paediatr
2017 | Journal article
DOI: 10.1111/apa.13923
SOURCE-WORK-ID:

136743407

PMID: 28510985
Contributors: Eriksson, M; Nilsson, A; Bennet, R
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Karolinska Institutet

Epstein-Barr Virus, but Not Cytomegalovirus, Latency Accelerates the Decay of Childhood Measles and Rubella Vaccine Responses-A 10-Year Follow-up of a Swedish Birth Cohort

Front Immunol
2017 | Journal article
DOI: 10.3389/fimmu.2017.01865
SOURCE-WORK-ID:

137259720

PMID: 29312344
Contributors: Lasaviciute, G; Björkander, S; Carvalho-Queiroz, C; Hed Myrberg, I; Nussbaum, B; Nilsson, C; Bemark, M; Nilsson, A; Sverremark-Ekström, E; Saghafian-Hedengren, S
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Karolinska Institutet

Hepatitis B Virus Vaccination in HIV-1-Infected Young Adults: A Tool to Reduce the Size of HIV-1 Reservoirs?

Front Immunol
2017 | Journal article
DOI: 10.3389/fimmu.2017.01966
SOURCE-WORK-ID:

137429421

PMID: 29375579
Contributors: Bekele, Y; Graham, RL; Soeria-Atmadja, S; Nasi, A; Zazzi, M; Vicenti, I; Naver, L; Nilsson, A; Chiodi, F
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Karolinska Institutet

Hypertriglyceridemia during asparaginase treatment in children with acute lymphoblastic leukemia correlates with antithrombin activity in adolescents

Pediatr Blood Cancer
2017 | Journal article
DOI: 10.1002/pbc.26559
SOURCE-WORK-ID:

136483036

PMID: 28440015
Contributors: Persson, L; Harila-Saari, A; Hed Myrberg, I; Heyman, M; Nilsson, A; Ranta, S
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Karolinska Institutet

T follicular helper cells and antibody response to Hepatitis B virus vaccine in HIV-1 infected children receiving ART

Sci Rep
2017 | Journal article
DOI: 10.1038/s41598-017-09165-6
SOURCE-WORK-ID:

136487767

PMID: 28827754
Contributors: Bekele, Y; Yibeltal, D; Bobosha, K; Andargie, TE; Lemma, M; Gebre, M; Mekonnen, E; Habtewold, A; Nilsson, A; Aseffa, A et al.
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Karolinska Institutet

The impact of pneumococcal conjugate vaccine on community-acquired pneumonia hospitalizations in children with comorbidity

European Journal of Pediatrics
2017-03-09 | Journal article
DOI: 10.1007/s00431-016-2843-2
Contributors: Ellinor Sterky; Rutger Bennet; Ann Lindstrand; Margareta Eriksson; Anna Nilsson
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A ten-year retrospective case series of glucocorticoid treatment of bacterial meningitis in children

Acta Paediatr
2016 | Journal article
DOI: 10.1111/apa.13443
SOURCE-WORK-ID:

134096119

PMID: 27102576
Contributors: Ygberg, S; Brauner, A; Chambers, BJ; Wiklund, C; Nilsson, A
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Karolinska Institutet

Diverse effects on vaccine-specific serum IgG titres and memory B cells upon methotrexate and anti-TNF-α therapy in children with rheumatic diseases: A cross-sectional study

Vaccine
2016 | Journal article
DOI: 10.1016/j.vaccine.2016.01.027
SOURCE-WORK-ID:

133187919

PMID: 26827664
Contributors: Ingelman-Sundberg, HM; Laestadius, Å; Chrapkowska, C; Mördrup, K; Magnusson, B; Sundberg, E; Nilsson, A
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Karolinska Institutet

Etiology of community acquired pneumonia among children in India: prospective, cohort study

J Glob Health
2015 | Journal article
DOI: 10.7189/jogh.05.020418
SOURCE-WORK-ID:

133348054

PMID: 26528392
Contributors: Mathew, JL; Singhi, S; Ray, P; Hagel, E; Saghafian-Hedengren, S; Bansal, A; Ygberg, S; Sodhi, KS; Kumar, BV; Nilsson, A
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Karolinska Institutet

Impaired Phenotype and Function of T Follicular Helper Cells in HIV-1-Infected Children Receiving ART

Medicine (Baltimore)
2015 | Journal article
DOI: 10.1097/MD.0000000000001125
SOURCE-WORK-ID:

131933151

PMID: 26166114
Contributors: Bekele, Y; Amu, S; Bobosha, K; Lantto, R; Nilsson, A; Endale, B; Gebre, M; Aseffa, A; Rethi, B; Howe, R et al.
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Karolinska Institutet

Selective loss of vaccine-specific memory B cells in a rhesus macaque model of chemotherapy: influence of doxorubicin on immunological memory

Haematologica
2015 | Journal article
DOI: 10.3324/haematol.2014.116111
SOURCE-WORK-ID:

131294098

PMID: 25552706
Contributors: Ingelman-Sundberg, HM; Saghafian-Hedengren, S; Jahnmatz, M; Eksborg, S; Jonker, M; Nilsson, A
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Karolinska Institutet

The aetiology of paediatric bloodstream infections changes after pneumococcal vaccination and group B streptococcus prophylaxis

Acta Paediatr
2015 | Journal article
DOI: 10.1111/apa.13070
SOURCE-WORK-ID:

131774353

PMID: 26060088
Contributors: Luthander, J; Bennet, R; Giske, CG; Nilsson, A; Eriksson, M
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Karolinska Institutet

Age and risk factors influence the microbial aetiology of bloodstream infection in children

Acta Paediatr.
2013 | Journal article
DOI:

10.1111/apa.12077

SOURCE-WORK-ID:

125973036

PMID:

23121094
Contributors: Luthander, J; Bennet, R; Giske, CG; Nilsson, A; Eriksson, M
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Karolinska Institutet

Kinetics of antibody and memory B cell responses after MMR immunization in children and young adults

Vaccine
2013 | Journal article
DOI:

10.1016/j.vaccine.2012.11.031

SOURCE-WORK-ID:

126144767

PMID:

23174196
Contributors: Kakoulidou, M; Ingelman-Sundberg, H; Johansson, E; Cagigi, A; Farouk, SE; Nilsson, A; Johansen, K
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Karolinska Institutet

Relation of activation-induced deaminase (AID) expression with antibody response to A(H1N1)pdm09 vaccination in HIV-1 infected patients

Vaccine
2013 | Journal article
DOI:

10.1016/j.vaccine.2013.03.002

SOURCE-WORK-ID:

126699128

PMID:

23499520
Contributors: Cagigi, A; Pensieroso, S; Ruffin, N; Sammicheli, S; Thorstensson, R; Pan-Hammarström, Q; Hejdeman, B; Nilsson, A; Chiodi, F
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Karolinska Institutet
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