Personal information

United States

Activities

Employment (4)

Genentech Inc: South San Francisco, CA, US

2022-06-21 to present | Scientist III (Small Molecule Process Chemistry)
Employment
Source: Self-asserted source
Kyle Clagg

Genentech Inc: South San Francisco, CA, US

2017-10-04 to 2022-06-20 | Scientist II (Small Molecule Process Chemistry)
Employment
Source: Self-asserted source
Kyle Clagg

Genentech Inc: South San Francisco, CA, US

2013-06-01 to 2017-10-03 | Scientist 1 (Small Molecule Process Chemistry)
Employment
Source: Self-asserted source
Kyle Clagg

University of California Berkeley: Berkeley, CA, US

2011-08-01 to 2013-05-31 | Undergraduate Research Assistant (College of Chemistry - Sarpong Lab)
Employment
Source: Self-asserted source
Kyle Clagg

Education and qualifications (1)

University of California: CA, CA, US

2009 to 2013 | Biochemistry
Education
Source: Self-asserted source
Kyle Clagg

Works (13)

C1 Functionalization of β-Carboline via Knochel–Hauser Base-Directed Metalation and Negishi Coupling

The Journal of Organic Chemistry
2024-12-06 | Journal article
Contributors: Jin Tan; Kyle Clagg; Haiming Zhang
Source: check_circle
Crossref

Data Science-Enabled Palladium-Catalyzed Enantioselective Aryl-Carbonylation of Sulfonimidamides

Journal of the American Chemical Society
2023-09-01 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Contributors: Lucy Van Dijk; Brittany C. Haas; Ngiap-Kie Lim; Kyle Clagg; Jordan J. Dotson; Sean M. Treacy; Katarzyna A. Piechowicz; Vladislav A. Roytman; Haiming Zhang; F. Dean Toste et al.
Source: Self-asserted source
Kyle Clagg

Second-Generation Atroposelective Synthesis of KRAS G12C Covalent Inhibitor GDC-6036

Organic Letters
2023-05-19 | Journal article
Contributors: Jie Xu; Ngiap-Kie Lim; Jacob C. Timmerman; Jeff Shen; Kyle Clagg; Ugo Orcel; Raphael Bigler; Etienne Trachsel; Roland Meier; Nicholas A. White et al.
Source: check_circle
Crossref

Atroposelective Negishi Coupling Optimization Guided by Multivariate Linear Regression Analysis: Asymmetric Synthesis of KRAS G12C Covalent Inhibitor GDC-6036

Journal of the American Chemical Society
2022-11-16 | Journal article
Contributors: Jie Xu; Samantha Grosslight; Kyle A. Mack; Sierra C. Nguyen; Kyle Clagg; Ngiap-Kie Lim; Jacob C. Timmerman; Jeff Shen; Nicholas A. White; Lauren E. Sirois et al.
Source: check_circle
Crossref

Efficient Manufacturing Process for the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) via a Crystallization-Driven Diastereoselective Pictet–Spengler Condensation

Organic Process Research & Development
2022-03-18 | Journal article
Contributors: Jie Xu; Cheol K. Chung; Andrew McClory; Kyle A. Mack; Michael E. Dalziel; Alec Fettes; Kyle Clagg; Ngiap-Kie Lim; Georg Wuitschik; Christian Jenny et al.
Source: check_circle
Crossref

First-Generation Asymmetric Synthesis of the Selective Estrogen Receptor Degrader GDC-9545 (Giredestrant) Featuring a Highly Efficient Pictet–Spengler Reaction and a C–N Coupling Reaction

Organic Process Research & Development
2022-03-18 | Journal article
Contributors: Jie Xu; Kyle Clagg; Ngiap-Kie Lim; Georg Wuitschik; Cheol K. Chung; Haiming Zhang; Francis Gosselin
Source: check_circle
Crossref

Practical Synthesis of a Stable Precursor for Positron Emission Tomography Imaging Agent 18F-GTP1

Organic Process Research & Development
2020-07-28 | Journal article
Part of ISSN: 1083-6160
Part of ISSN: 1520-586X
Source: Self-asserted source
Kyle Clagg

Phosphoramidates as Steering Elements for Highly Selective Access to Complementary Imidazo[1,2-a]pyrimidine Isomers

Organic Letters
2019-12-06 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Kyle Clagg

A telescoped Knochel-Hauser/Kumada-Corriu coupling strategy to functionalized aromatic heterocycles

Tetrahedron Letters
2019-01 | Journal article
Part of ISSN: 0040-4039
Source: Self-asserted source
Kyle Clagg

A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine)

Journal of the American Chemical Society
2018-07-05 | Journal article
Part of ISSN: 0002-7863
Part of ISSN: 1520-5126
Source: Self-asserted source
Kyle Clagg

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)

Journal of Medicinal Chemistry
2017-11-22 | Journal article
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Source: Self-asserted source
Kyle Clagg

Synthesis of Indole-2-carboxylate Derivatives via Palladium-Catalyzed Aerobic Amination of Aryl C–H Bonds

Organic Letters
2016-08-05 | Journal article
Part of ISSN: 1523-7060
Part of ISSN: 1523-7052
Source: Self-asserted source
Kyle Clagg

Experimental and Computational Studies of the Diastereoselective Alkylations of 3-Substituted γ-Sultams

The Journal of Organic Chemistry
2015-01-02 | Journal article
Part of ISSN: 0022-3263
Part of ISSN: 1520-6904
Source: Self-asserted source
Kyle Clagg