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Scopus Author ID: 14030421600
ResearcherID: G-9547-2012

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Works (44)

Ligand Binding Free Energy Evaluation by Monte Carlo Recursion

2022-08-03 | Preprint
DOI: 10.1101/2022.08.01.502202
Contributors: Joao Victor de Souza; Victor H. R. Nogueira; Alessandro S. Nascimento
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Crossref

A scalable screening of E. coli strains for recombinant protein expression

PLOS ONE
2022-07-25 | Journal article
DOI: 10.1371/journal.pone.0271403
Contributors: Luana G. Morão; Travis Beddoe; Lívia R. Manzine; Lívia Oliveira D. Clementino; Carsten Wrenger; Alessandro S. Nascimento
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The β-lactam Ticarcillin is a Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase binder

2021-11-05 | Preprint
DOI: 10.1101/2021.11.05.467346
Contributors: Erika Chang de Azevedo; Alessandro S. Nascimento
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Crossref

Tetrazoles as PPARγ ligands: A structural and computational investigation

Journal of Molecular Graphics and Modelling
2021-07 | Journal article
DOI: 10.1016/j.jmgm.2021.107932
Contributors: Karina de Paula; Jademilson C. Santos; Ana Carolina Mafud; Alessandro S. Nascimento
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Crossref

A Scalable Screening ofE. coliStrains for Recombinant Protein Expression

2021-03-09 | Preprint
DOI: 10.1101/2021.03.09.434560
Contributors: Luana G. Morão; Lívia R. Manzine; Lívia Oliveira D. Clementino; Carsten Wrenger; Alessandro S. Nascimento
Source: check_circle
Crossref

Tetrazoles as PPARγ ligands: A Structural and Computational Investigation

2021-02-17 | Preprint
DOI: 10.1101/2021.02.17.431624
Contributors: Karina de Paula; Jademilson C. Santos; Ana Carolina Mafud; Alessandro S. Nascimento
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Crossref

Essential Metabolic Routes as a Way to ESKAPE from Antibiotic Resistance

2019-10-25 | Other
DOI: 10.1101/817015
Contributors: Angélica Luana C. Barra; Lívia de Oliveira C. Dantas; Luana Galvão Morão; Raíssa F. Gutierrez; Igor Polikarpov; Carsten Wrenger; Alessandro S. Nascimento
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Crossref

Comparative Analysis of Electrostatic Models for Ligand Docking

2019-03-14 | Other
DOI: 10.1101/577643
Contributors: Geraldo Rodrigues Sartori; Alessandro S. Nascimento
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Crossref

Energy Landscape of the Domain Movement in Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase

2019-01-30 | Other
DOI: 10.1101/535138
Contributors: Erika Chang de Azevedo; Alessandro S. Nascimento
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Structural insights into β-glucosidase transglycosylation based on biochemical, structural and computational analysis of two GH1 enzymes from Trichoderma harzianum

New Biotechnology
2018 | Journal article
DOI: 10.1016/j.nbt.2017.08.012
EID:

2-s2.0-85029599895
Contributors: Florindo, R.N.; Souza, V.P.; Mutti, H.S.; Camilo, C.; Manzine, L.R.; Marana, S.R.; Polikarpov, I.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Structure, computational and biochemical analysis of PcCel45A endoglucanase from Phanerochaete chrysosporium and catalytic mechanisms of GH45 subfamily C members

Scientific Reports
2018 | Journal article
DOI: 10.1038/s41598-018-21798-9
EID:

2-s2.0-85042803847
Contributors: Godoy, A.S.; Pereira, C.S.; Ramia, M.P.; Silveira, R.L.; Camilo, C.M.; Kadowaki, M.A.; Lange, L.; Busk, P.K.; Nascimento, A.S.; Skaf, M.S. et al.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Low-resolution envelope, biophysical analysis and biochemical characterization of a short-chain specific and halotolerant carboxylesterase from Bacillus licheniformis

International Journal of Biological Macromolecules
2018-12 | Journal article
DOI: 10.1016/j.ijbiomac.2018.10.003
Contributors: Aline M. Nakamura; Marco Antonio Seiki Kadowaki; André Godoy; Alessandro S. Nascimento; Igor Polikarpov
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GH43 endo-arabinanase from Bacillus licheniformis: Structure, activity and unexpected synergistic effect on cellulose enzymatic hydrolysis

International Journal of Biological Macromolecules
2018-10 | Journal article
DOI: 10.1016/j.ijbiomac.2018.05.157
Contributors: Erick Giancarlo S. Farro; Ana Elisa T. Leite; Isabela A. Silva; Jefferson G. Filgueiras; Eduardo R. de Azevedo; Igor Polikarpov; Alessandro S. Nascimento
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Crossref

Structural and biochemical characterization of a GH3 β-glucosidase from the probiotic bacteria Bifidobacterium adolescentis

Biochimie
2018-05 | Journal article
DOI: 10.1016/j.biochi.2018.03.007
Contributors: Renata N. Florindo; Valquiria P. Souza; Lívia R. Manzine; Cesar M. Camilo; Sandro R. Marana; Igor Polikarpov; Alessandro S. Nascimento
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Crossref

An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position

Scientific Reports
2017 | Journal article
DOI: 10.1038/s41598-017-03774-x
EID:

2-s2.0-85020710359
Contributors: Souza, P.C.T.; Textor, L.C.; Melo, D.C.; Nascimento, A.S.; Skaf, M.S.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Structural and biochemical data of Trichoderma harzianum GH1 β-glucosidases

Data in Brief
2017 | Journal article
DOI: 10.1016/j.dib.2017.09.044
EID:

2-s2.0-85030715631
Contributors: Florindo, R.N.; Souza, V.P.; Mutti, H.S.; Margarido, L.R.M.; Camilo, C.; Marana, S.R.; Polikarpov, I.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Towards a critical evaluation of an empirical and volume-based solvation function for ligand docking

PLOS ONE
2017-03-21 | Journal article
DOI: 10.1371/journal.pone.0174336
Contributors: Heloisa S. Muniz; Danilo Roccatano; Alessandro S. Nascimento
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Crossref

Crystal structure of β1→6-galactosidase from Bifidobacterium bifidum S17: trimeric architecture, molecular determinants of the enzymatic activity and its inhibition by α-galactose

FEBS Journal
2016 | Journal article
DOI: 10.1111/febs.13908
EID:

2-s2.0-84991666278
Contributors: Godoy, A.S.; Camilo, C.M.; Kadowaki, M.A.; Muniz, H.D.S.; Espirito Santo, M.; Murakami, M.T.; Nascimento, A.S.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Structure-based virtual screening and discovery of new PPARδ/γ dual agonist and PPARδ and γ agonists

PLoS ONE
2015 | Journal article
DOI: 10.1371/journal.pone.0118790
EID:

2-s2.0-84929493665
Contributors: Maltarollo, V.G.; Togashi, M.; Nascimento, A.S.; Honorio, K.M.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Successes and pitfalls in scoring molecular interactions

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
2015 | Book
EID:

2-s2.0-84925280131
Contributors: Muniz, H.S.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Ligand- and receptor-based docking with LiBELa

Journal of Computer-Aided Molecular Design
2015-08 | Journal article
DOI: 10.1007/s10822-015-9856-1
Contributors: Heloisa dos Santos Muniz; Alessandro S. Nascimento
Source: check_circle
Crossref

Identification of a new hormone-binding site on the surface of thyroid hormone receptor

Molecular Endocrinology
2014 | Journal article
DOI: 10.1210/me.2013-1359
EID:

2-s2.0-84897940546
Contributors: Souza, P.C.T.; Puhl, A.C.; Martínez, L.; Aparício, R.; Nascimento, A.S.; Figueira, A.C.M.; Nguyen, P.; Webb, P.; Skaf, M.S.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Insights into the structure and function of fungal β-mannosidases from glycoside hydrolase family 2 based on multiple crystal structures of the Trichoderma harzianum enzyme

The FEBS journal
2014 | Journal article
DOI: 10.1111/febs.12894
EID:

2-s2.0-84909955528
Contributors: Nascimento, A.S.; Muniz, J.R.; Aparício, R.; Golubev, A.M.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

2-({1-[2-(Methylsulfanyl)phenyl]-1H-tetrazol-5-yl}sulfanyl)acetic acid

Acta Crystallographica Section E: Structure Reports Online
2013 | Journal article
DOI: 10.1107/S160053681300980X
EID:

2-s2.0-84877255569
Contributors: Mafud, A.C.; Mascarenhas, Y.P.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

4-{5-[(2-Bromobenzyl)sulfanyl]-1H-tetrazol-1-yl}benzoic acid

Acta Crystallographica Section E: Structure Reports Online
2013 | Journal article
DOI: 10.1107/S1600536813014840
EID:

2-s2.0-84879936590
Contributors: Mafud, A.C.; Mascarenhas, Y.P.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

MolShaCS: A free and open source tool for ligand similarity identification based on Gaussian descriptors

European Journal of Medicinal Chemistry
2013 | Journal article
DOI: 10.1016/j.ejmech.2012.11.013
EID:

2-s2.0-84870662439
Contributors: Vaz De Lima, L.A.C.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier
grade
Preferred source (of 2)‎

Structure-based identification of novel PPAR gamma ligands

Bioorganic and Medicinal Chemistry Letters
2013 | Journal article
DOI: 10.1016/j.bmcl.2013.09.010
EID:

2-s2.0-84885152258
Contributors: Da Silva, F.M.C.; Dos Santos, J.C.; Campos, J.L.O.; Mafud, A.C.; Polikarpov, I.; Figueira, A.C.M.; Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Medium chain fatty acids are selective peroxisome proliferator activated receptor (PPAR) γ activators and Pan-PPAR partial agonists

PLoS ONE
2012 | Journal article
DOI: 10.1371/journal.pone.0036297
EID:

2-s2.0-84861381281
Contributors: Liberato, M.V.; Nascimento, A.S.; Ayers, S.D.; Lin, J.Z.; Cvoro, A.; Silveira, R.L.; Martínez, L.; Souza, P.C.T.; Saidemberg, D.; Deng, T. et al.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Molecular basis of the thermostability and thermophilicity of laminarinases: X-ray structure of the hyperthermostable laminarinase from rhodothermus marinus and molecular dynamics simulations

Journal of Physical Chemistry B
2011 | Journal article
DOI: 10.1021/jp200330z
EID:

2-s2.0-79959369421
Contributors: Bleicher, L.; Prates, E.T.; Gomes, T.C.F.; Silveira, R.L.; Nascimento, A.S.; Rojas, A.L.; Golubev, A.; Martínez, L.; Skaf, M.S.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Crystal structure and statistical coupling analysis of highly glycosylated peroxidase from royal palm tree (Roystonea regia)

Journal of Structural Biology
2010 | Journal article
DOI: 10.1016/j.jsb.2009.10.009
EID:

2-s2.0-74849110815
Contributors: Watanabe, L.; de Moura, P.R.; Bleicher, L.; Nascimento, A.S.; Zamorano, L.S.; Calvete, J.J.; Sanz, L.; Pérez, A.; Bursakov, S.; Roig, M.G. et al.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

On the denaturation mechanisms of the ligand binding domain of thyroid hormone receptors

Journal of Physical Chemistry B
2010 | Journal article
DOI: 10.1021/jp911554p
EID:

2-s2.0-76249104052
Contributors: Martínez, L.; Souza, P.C.T.; Garcia, W.; Batista, F.A.H.; Portugal, R.V.; Nascimento, A.S.; Nakahira, M.; Lima, L.M.T.R.; Polikarpov, I.; Skaf, M.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Structural requirement for PPARγ binding revealed by a meta analysis of holo-crystal structures

Biochimie
2010 | Journal article
DOI: 10.1016/j.biochi.2010.01.018
EID:

2-s2.0-77951024557
Contributors: Nascimento, A.S.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier
grade
Preferred source (of 2)‎

Crystallization and preliminary X-ray diffraction analysis of human IL-22 bound to its soluble decoy receptor IL-22BP

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2009 | Journal article
DOI: 10.1107/S1744309108042309
EID:

2-s2.0-59749089081
Contributors: Watanabe, L.; De Moura, P.R.; Nascimento, A.S.; Colau, D.; Dumoutier, L.; Renauld, J.-C.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Gaining ligand selectivity in thyroid hormone receptors via entropy

Proceedings of the National Academy of Sciences of the United States of America
2009 | Journal article
DOI: 10.1073/pnas.0911024106
EID:

2-s2.0-73949144655
Contributors: Martínez, L.; Nascimento, A.S.; Nunes, F.M.; Phillips, K.; Aparicio, R.; Dias, S.M.G.; Figueira, A.C.M.; Lin, J.H.; Nguyen, P.; Apriletti, J.W. et al.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Catalytic mechanism of inulinase from Arthrobacter sp. S37

Biochemical and Biophysical Research Communications
2008 | Journal article
DOI: 10.1016/j.bbrc.2008.03.126
EID:

2-s2.0-44149116967
Contributors: Kim, K.-Y.; Nascimento, A.S.; Golubev, A.M.; Polikarpov, I.; Kim, C.-S.; Kang, S.-I.; Kim, S.-I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Interleukin-22 forms dimers that are recognized by two interleukin-22R1 receptor chains

Biophysical Journal
2008 | Journal article
DOI: 10.1529/biophysj.107.112664
EID:

2-s2.0-41449114478
Contributors: De Neto, M.O.; Ferreira Jr, J.R.; Colau, D.; Fischer, H.; Nascimento, A.S.; Craievich, A.F.; Dumoutier, L.; Renauld, J.-C.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Statistical Coupling Analysis of Aspartic Proteinases Based on Crystal Structures of the Trichoderma reesei Enzyme and Its Complex with Pepstatin A

Journal of Molecular Biology
2008 | Journal article
DOI: 10.1016/j.jmb.2008.07.043
EID:

2-s2.0-50149090211
Contributors: Nascimento, A.S.; Krauchenco, S.; Golubev, A.M.; Gustchina, A.; Wlodawer, A.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

The MX2 macromolecular crystallography beamline: A wiggler X-ray source at the LNLS

Journal of Synchrotron Radiation
2008 | Journal article
DOI: 10.1107/S0909049508034870
EID:

2-s2.0-57849118819
Contributors: Guimarães, B.G.; Sanfelici, L.; Neuenschwander, R.T.; Rodrigues, F.; Grizolli, W.C.; Raulik, M.A.; Piton, J.R.; Meyer, B.C.; Nascimento, A.S.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Crystal structures of Leptospira interrogans FAD-containing ferredoxin-NADP<sup>+</sup> reductase and its complex with NADP<sup>+</sup>

BMC Structural Biology
2007 | Journal article
DOI: 10.1186/1472-6807-7-69
EID:

2-s2.0-37349085779
Contributors: Nascimento, A.S.; Catalano-Dupuy, D.L.; Bernardes, A.; Neto, M.D.O.; Santos, M.A.M.; Ceccarelli, E.A.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Purification, crystallization and preliminary X-ray diffraction analysis of royal palm tree (Roystonea regia) peroxidase

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2007 | Journal article
DOI: 10.1107/S174430910703984X
EID:

2-s2.0-34548437720
Contributors: Watanabe, L.; Nascimento, A.S.; Zamorano, L.S.; Shnyrov, V.L.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Crystallization and preliminary X-ray diffraction analysis of rat protein tyrosine phosphatase η

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2006 | Journal article
DOI: 10.1107/S1744309106031058
EID:

2-s2.0-33748515940
Contributors: Matozo, H.C.; Nascimento, A.S.; Santos, M.A.M.; Iuliano, R.; Fusco, A.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Crystallization and preliminary X-ray diffraction studies of ferredoxin reductase from Leptospira interrogans

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2006 | Journal article
DOI: 10.1107/S1744309106020136
EID:

2-s2.0-33745727134
Contributors: Nascimento, A.S.; Ferrarezi, T.; Catalano-Dupuy, D.L.; Ceccarelli, E.A.; Polikarpov, I.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Structural Rearrangements in the Thyroid Hormone Receptor Hinge Domain and Their Putative Role in the Receptor Function

Journal of Molecular Biology
2006 | Journal article
DOI: 10.1016/j.jmb.2006.05.008
EID:

2-s2.0-33745670369
Contributors: Nascimento, A.S.; Dias, S.M.G.; Nunes, F.M.; Aparício, R.; Ambrosio, A.L.B.; Bleicher, L.; Figueira, A.C.M.; Santos, M.A.M.; Neto, M.d.O.; Fischer, H. et al.
Source: Self-asserted source
Alessandro Nascimento via Scopus - Elsevier

Crystallization and Preliminary Crystallographic Analysis of Laminarinase from Rhodothermus marinus: A Case of Pseudomerohedral Twinning

Journal article
DOI:

10.2174/092986608786071139
Source: Self-asserted source
Alessandro Nascimento
grade
Preferred source (of 2)‎

Peer review (25 reviews for 11 publications/grants)

Review activity for Biophysical reviews. (2)
Review activity for Brazilian journal of microbiology. (2)
Review activity for ChemBioChem. (1)
Review activity for Computational biology and chemistry. (1)
Review activity for International journal of biological macromolecules. (1)
Review activity for Journal of chemical information and modeling. (10)
Review activity for Journal of chemical theory and computation : (1)
Review activity for Journal of molecular graphics & modelling. (1)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
Review activity for The journal of physical chemistry. (4)
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