Personal information

Emails & domains

Verified email addresses

Other IDs

ResearcherID: IXW-6790-2023
Scopus Author ID: 56694812600
Loop profile: 2548305

Keywords

Neurosciences, Neuropharmacology, Electrophysiology, Neurodegenerative diseases

Countries

United States, Pakistan

Biography

As a Postdoctoral fellow at Feinberg School of Medicine, Northwestern University, Chicago, my research is focused on Alzheimer’s disease in aged rats involving electrophysiological and behavioral studies.

My PhD research was based on the molecular mechanisms of agmatine (a polyamine) as a neuromodulator that revealed a significant activity on GABA, glutamate, and monoamine (dopamine, norepinephrine, and serotonin) neurotransmitters at the NMDA and AMPA receptor levels.

I was a Research Associate at the Aga Khan University, Karachi, working on various cardiac and respiratory research projects related to experimental physiology and proteomics.

I've earned expertise in the electrophysiology and neuropharmacology of neurodegenerative diseases and has been involved in research based on animal modeling, clinical biochemistry, molecular biology, neurotoxicity, neurotransmitters, and behavioral sciences.

Activities

Collapse all

Employment (4)

Northwestern University: Chicago, IL, US

2023-05 to present | Postdoctoral fellow (Neuroscience)
Employment
Source: Self-asserted source
Hira Rafi

Aga Khan University: Karachi, PK

2021-09-01 to 2023-02-04 | Research Associate (Department of Biological and Biomedical Sciences)
Employment
Source: Self-asserted source
Hira Rafi

Aga Khan University: Karachi, PK

2019-10-28 to 2021-08-31 | Research Associate (Grant) (Department of Biological and Biomedical Sciences)
Employment
Source: Self-asserted source
Hira Rafi

University of Karachi: Karachi, PK

2017-01-01 to 2017-06-30 | Teaching Assistant (Department of Biochemistry)
Employment
Source: Self-asserted source
Hira Rafi

Education and qualifications (3)

University of Karachi: Karachi, Sindh, PK

2018-02-01 to 2022-11-23 | PhD (Department of Biochemistry)
Education
Source: Self-asserted source
Hira Rafi

University of Karachi: Karachi, PK

2015-07-24 to 2018-01-31 | MS (Department of Biochemistry)
Education
Source: Self-asserted source
Hira Rafi

University of Karachi: Karachi, PK

2013-01-01 to 2015-01-01 | Graduation (Department of Biochemistry)
Education
Source: Self-asserted source
Hira Rafi

Professional activities (1)

Society for Neuroscience: Washington D.C., District of Columbia, US

2023-08-01 to present | Individual Membership Postdoctoral
Membership
Source: Self-asserted source
Hira Rafi

Works (25)

Upregulation of Nrf2 in myocardial infarction and ischemia-reperfusion injury of the heart

Plos One
2024 | Journal article
DOI: 10.1371/JOURNAL.PONE.0299503
WOSUID: WOS:001190798000027
Contributors: Zuberi, Sahar; Rafi, Hira; Hussain, Azhar; Hashmi, Satwat
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Agmatine Improves Oxidative Stress Profiles in Rat Brain Tissues Induced by Sodium Azide

Current Chemical Biology
2024-12 | Journal article
DOI: 10.2174/0122127968308662240926114002
Contributors: Hira Rafi; Hamna Rafiq; Muhammad Farhan
Source: check_circle
Crossref

Peer Review of “Establishment of a Novel Fetal Ovine Heart Cell Line by Spontaneous Cell Fusion: Experimental Study” (Preprint)

2024-06-17 | Preprint
DOI: 10.2196/preprints.63336
Contributors: Hira Rafi
Source: check_circle
Crossref

Pharmacological profile of agmatine: An in-depth overview

Neuropeptides
2024-04 | Journal article
DOI: 10.1016/j.npep.2024.102429
Part of ISSN: 0143-4179
Contributors: Hira Rafi; Hamna Rafiq; Muhammad Farhan
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 2)‎

Agmatine alleviates brain oxidative stress induced by sodium azide

Research Square
2023 | Other
DOI: 10.21203/rs.3.rs-3244002
EID:

2-s2.0-85171346867
Contributors: Rafi, H.; Rafiq, H.; Farhan, M.
Source: Self-asserted source
Hira Rafi via Scopus - Elsevier

Role of Nrf2 in myocardial infarction and ischemia-reperfusion injury

Physiology
2023-05 | Journal article
DOI: 10.1152/physiol.2023.38.s1.5734743
Part of ISSN: 1548-9213
Part of ISSN: 1548-9221
Contributors: Sahar Zuberi; Hira Rafi; Azhar Hussain; Satwat Hashmi
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 2)‎

Inhibition of drug induced Parkinsonism by chronic supplementation of quercetin in haloperidol-treated wistars

Pakistan Journal of Pharmaceutical Sciences
2022 | Journal article
DOI: 10.36721/PJPS.2022.35.6.REG.1655-1662.1
WOSUID: WOS:000895376600019
Contributors: Rafiq, Hamna; Farhan, Muhammad; Rafi, Hira; Rehman, Sadia; Arshad, Maria; Shakeel, Sarah
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Quercetin impact against psychological disturbances induced by fat rich diet

Pakistan Journal of Pharmaceutical Sciences
2022 | Journal article
DOI: 10.36721/PJPS.2022.35.5.REG.1295-1300.1
WOSUID: WOS:000863318200002
Contributors: Farhan, Muhammad; Rafiq, Hamna; Rafi, Hira; Rehman, Sadia; Arshad, Maria
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Inhibition of drug induced Parkinsonism by chronic supplementation of quercetin in haloperidol-treated wistars.

Pakistan journal of pharmaceutical sciences
2022-11-01 | Journal article
PMID: 36789825
Contributors: Rafiq H; Farhan M; Rafi H; Rehman S; Arshad M; Shakeel S
Source: Self-asserted source
Hira Rafi

Quercetin impact against psychological disturbances induced by fat rich diet.

Pakistan journal of pharmaceutical sciences
2022-09-01 | Journal article
PMID: 36451556
Contributors: Farhan M; Rafiq H; Rafi H; Rehman S; Arshad M
Source: Self-asserted source
Hira Rafi

Impact of SARS-CoV2 Treatment on Development of Sensorineural Hearing Loss

Proceedings of the Pakistan Academy of Sciences:
2021 | Journal article
Contributors: Hira Rafi
Source: Self-asserted source
Hira Rafi

Antagonization of monoamine reuptake transporters by agmatine improves anxiolytic and locomotive behaviors commensurate with fluoxetine and methylphenidate

Beni-Suef University Journal of Basic and Applied Sciences
2021-12 | Journal article
DOI: 10.1186/s43088-021-00118-7
Part of ISSN: 2314-8543
Contributors: Hira Rafi; Hamna Rafiq; Muhammad Farhan
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 3)‎

Inhibition of NMDA receptors by agmatine is followed by GABA/glutamate balance in benzodiazepine withdrawal syndrome

Beni-Suef University Journal of Basic and Applied Sciences
2021-12 | Journal article
DOI: 10.1186/s43088-021-00125-8
Part of ISSN: 2314-8543
Contributors: Hira Rafi; Hamna Rafiq; Muhammad Farhan
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 3)‎

Chronic agmatine treatment modulates behavioral deficits induced by chronic unpredictable stress in wistar rats

Journal of Pharmaceutical and Biological Sciences
2020-12-28 | Journal article
DOI: 10.18231/2320-1924.2018.0019
Part of ISSN: 2320-1924
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 2)‎

Comparative Effectiveness of Agmatine and Choline Treatment in Rats with Cognitive Impairment Induced by AlCl3 and Forced Swim Stress

Current Clinical Pharmacology
2020-12-15 | Journal article
DOI: 10.2174/1574884714666191016152143
Part of ISSN: 1574-8847
Contributors: Hira Rafi; Fahad Ahmad; Javaria Anis; Ruba Khan; Hamna Rafiq; Muhammad Farhan
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 3)‎

Neuroethological Study of AlCl3 and Chronic Forced Swim Stress Induced Memory and Cognitive Deficits in Albino Rats.

The Journal of Neurobehavioral Sciences
2019 | Journal article
DOI: 10.5455/jnbs.1558487053
Part of ISSN: 2149-1909
Contributors: Hira Rafi; Hamna Rafiq; Ruba Khan; Fahad Ahmad; Javaria Anis; Muhammad Farhan
Source: Self-asserted source
Hira Rafi

Study of Mental Illness in Rat Model of Sodium Azide Induced Oxidative Stress

Journal of Pharmacy and Nutrition Sciences
2019-08-05 | Journal article
DOI: 10.29169/1927-5951.2019.09.04.3
Part of ISSN: 1927-5951
Part of ISSN: 2223-3806
Contributors: Muhammad Farhan; Hira Rafi; Hamna Rafiq; Fahad Siddiqui; Ruba Khan; Javeria Anis
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 3)‎

Determination of metabolic and psychological consequences of quercetin repeated administration in male rats: age dependent study

Malaysian Journal of Biochemistry and Molecular Biology
2019-04 | Journal article
EID:

2-s2.0-85068425343

Part of ISSN: 15112616
Contributors: Hira Rafi
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 2)‎

Neuroprotective role of quercetin against neurotoxicity induced by lead acetate in male rats

International Journal of Biology and Biotechnology
2019-02-16 | Journal article
Contributors: Hira Rafi
Source: Self-asserted source
Hira Rafi

Behavioral evidence of neuropsychopharmacological effect of imipramine in animal model of unpredictable stress induced depression

International Journal of Biology and Biotechnology
2018 | Journal article
Contributors: Hira Rafi
Source: Self-asserted source
Hira Rafi

Combined effect of soil amendment with oil cakes and seed priming in the control of root rot fungi of leguminous and non-leguminous crops

Pakistan Journal of Botany
2016 | Journal article
EID:

2-s2.0-84973639283

Part of ISSN: 05563321
Contributors: Rafi, H.; Dawar, S.; Tariq, M.
Source: Self-asserted source
Hira Rafi via Scopus - Elsevier

Dapoxetine: An Innovative Approach in the Therapeutic Management In Animal Model of Depression

2016-01 | Journal article
DOI: 10.22200/PJPR.2016115-22
Contributors: Hira Rafi
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 2)‎

Seed priming with extracts of Acacia nilotica (L.) Willd. ex Delile and Sapindus mukorossi (L.) plant parts in the control of root rot fungi and growth of plants

Pakistan Journal of Botany
2015 | Journal article
EID:

2-s2.0-84932082591

Part of ISSN: 05563321
Contributors: Rafi, H.; Dawar, S.; Javed Zaki, M.
Source: Self-asserted source
Hira Rafi via Scopus - Elsevier

Dapoxetine Treatment Leads to Attenuation of Chronic Unpredictable Stress Induced Behavioral Deficits in Rats Model of Depression

Journal of Pharmacy and Nutrition Sciences
2015-08-05 | Journal article
DOI: 10.6000/1927-5951.2015.05.04.2
Part of ISSN: 1927-5951
Part of ISSN: 2223-3806
Contributors: Muhammad Farhan; Hira Rafi; Hamna Rafiq
Source: Self-asserted source
Hira Rafi
grade
Preferred source (of 3)‎

Prevalence of Depression in Animal Model of High Fat Diet Induced Obesity

Journal of Pharmacy and Nutrition Sciences
2015-06-05 | Journal article
DOI: 10.6000/1927-5951.2015.05.03.6
Part of ISSN: 1927-5951
Part of ISSN: 2223-3806
Contributors: Muhammad Farhan; Hamna Rafiq; Hira Rafi
Source: Self-asserted source
Hira Rafi

Peer review (68 reviews for 17 publications/grants)

Review activity for American journal of psychiatry and neuroscience. (1)
Review activity for Brain research. (17)
Review activity for Brain research. (7)
Review activity for Cellular and molecular neurobiology. (2)
Review activity for Endocrine and metabolic science. (12)
Review activity for Frontiers in nutrition. (2)
Review activity for Gene & protein in disease. (1)
Review activity for JMIR diabetes. (1)
Review activity for JMIR formative research. (4)
Review activity for JMIR research protocols. (4)
Review activity for JMIR. (6)
Review activity for Metabolic brain disease. (1)
Review activity for Molecular neurobiology. (1)
Review activity for Naunyn-Schmiedeberg's archives of pharmacology. (1)
Review activity for PeerJ. (4)
Review activity for Qeios. (2)
Review activity for Toxicology mechanisms and methods. (2)
How many people are using ORCID?