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Employment (2)

University of Michigan Medical School: Ann Arbor, MI, US

2017 to present | Assistant Professor (Biological Chemistry)
Employment
Source: Self-asserted source
Ryan Baldridge

Harvard Medical School: Boston, MA, US

2013 to 2017 | Postdoctoral Fellow (Cell Biology)
Employment
Source: Self-asserted source
Ryan Baldridge

Education and qualifications (3)

Vanderbilt University: Nashville, TN, US

2007 to 2013 | Ph.D. (Biological Sciences)
Education
Source: Self-asserted source
Ryan Baldridge

Northern Kentucky University: Highland Heights, KY, US

2003 to 2007 | B.S. (Biological Sciences)
Education
Source: Self-asserted source
Ryan Baldridge

Northern Kentucky University: Highland Heights, KY, US

2003 to 2007 | B.S. (Chemistry)
Education
Source: Self-asserted source
Ryan Baldridge

Funding (3)

Protein quality control at eukaryotic membranes.

2018-08-15 to 2023-07-31 | Grant
National Institute of General Medical Sciences (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.7725924
GRANT_NUMBER: R35GM128592
Source: Self-asserted source
Ryan Baldridge via DimensionsWizard

Investigating the mechanism of retro-translocation by ERAD

2018 to 2019 | Award
Damon Runyon Cancer Research Foundation (NY, NY, US)
Source: Self-asserted source
Ryan Baldridge

Investigating the mechanism of retro-translocation by ERAD

2014 to 2017 | Award
Damon Runyon Cancer Research Foundation (NY, NY, US)
GRANT_NUMBER:

DRG2184-14
Source: Self-asserted source
Ryan Baldridge

Works (18)

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

eLife
2024-11-12 | Journal article
DOI: 10.7554/eLife.89606.3
Contributors: Rachel Sharninghausen; Jiwon Hwang; Devon D Dennison; Ryan D Baldridge
Source: check_circle
Crossref

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

eLife
2024-11-12 | Journal article
DOI: 10.7554/eLife.89606
Contributors: Rachel Sharninghausen; Jiwon Hwang; Devon D Dennison; Ryan D Baldridge
Source: check_circle
Crossref

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

2024-09-30 | Preprint
DOI: 10.7554/eLife.89606.2
Contributors: Rachel Sharninghausen; Jiwon Hwang; Devon D Dennison; Ryan D Baldridge
Source: check_circle
Crossref

Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD

Nature Communications
2024-02-13 | Journal article
DOI: 10.1038/s41467-024-45541-3
Contributors: Basila Moochickal Assainar; Kaushik Ragunathan; Ryan D. Baldridge
Source: check_circle
Crossref

Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function

Cell Reports
2023-11 | Journal article
DOI: 10.1016/j.celrep.2023.113451
Contributors: Brian G. Peterson; Jiwon Hwang; Jennifer E. Russ; Jeremy W. Schroeder; P. Lydia Freddolino; Ryan D. Baldridge
Source: check_circle
Crossref

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

2023-09-05 | Preprint
DOI: 10.7554/eLife.89606.1
Contributors: Rachel Sharninghausen; Jiwon Hwang; Devon Dennison; Ryan D. Baldridge
Source: check_circle
Crossref

Direct observation of autoubiquitination for an integral membrane ubiquitin ligase in ERAD

2023-06-22 | Preprint
DOI: 10.1101/2023.06.20.545802
Contributors: Basila Moochickal Assainar; Kaushik Ragunathan; Ryan D. Baldridge
Source: check_circle
Crossref

Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen

2023-06-22 | Preprint
DOI: 10.1101/2023.06.21.546000
Contributors: Rachel Sharninghausen; Jiwon Hwang; Devon D. Dennison; Ryan D. Baldridge
Source: check_circle
Crossref

Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function

2023-04-03 | Preprint
DOI: 10.1101/2023.04.03.535444
Contributors: Brian G. Peterson; Jiwon Hwang; Jennifer E. Russ; Jeremy Schroeder; Peter L. Freddolino; Ryan D. Baldridge
Source: check_circle
Crossref

The ERAD system is restricted by elevated ceramides

Science Advances
2023-01-13 | Journal article
DOI: 10.1126/sciadv.add8579
Contributors: Jiwon Hwang; Brian G. Peterson; Jeffrey Knupp; Ryan D. Baldridge
Source: check_circle
Crossref

Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1

eLife
2019-11-12 | Journal article
DOI: 10.7554/eLife.50903
Contributors: Brian G Peterson; Morgan L Glaser; Tom A Rapoport; Ryan D Baldridge
Source: check_circle
Crossref

Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD

Cell
2016-07 | Journal article
DOI: 10.1016/j.cell.2016.05.048
Part of ISSN: 0092-8674
Source: Self-asserted source
Ryan Baldridge

Role of Flippases, Scramblases and Transfer Proteins in Phosphatidylserine Subcellular Distribution

Traffic
2015-01 | Journal article
DOI: 10.1111/tra.12233
Part of ISSN: 1398-9219
Source: Self-asserted source
Ryan Baldridge

Phosphatidylserine flipping enhances membrane curvature and negative charge required for vesicular transport

The Journal of Cell Biology
2013-09-16 | Journal article
DOI: 10.1083/jcb.201305094
Part of ISSN: 0021-9525
Part of ISSN: 1540-8140
Source: Self-asserted source
Ryan Baldridge

Type IV P-type ATPases Distinguish Mono-versusDiacyl Phosphatidylserine Using a Cytofacial Exit Gate in the Membrane Domain

Journal of Biological Chemistry
2013-07-05 | Journal article
DOI: 10.1074/jbc.m113.476911
Part of ISSN: 0021-9258
Part of ISSN: 1083-351X
Source: Self-asserted source
Ryan Baldridge

Two-gate mechanism for phospholipid selection and transport by type IV P-type ATPases

Proceedings of the National Academy of Sciences
2013-01-29 | Journal article
DOI: 10.1073/pnas.1216948110
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Ryan Baldridge

Phospholipid flippases: Building asymmetric membranes and transport vesicles

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2012-08 | Journal article
DOI: 10.1016/j.bbalip.2011.12.007
Part of ISSN: 1388-1981
Source: Self-asserted source
Ryan Baldridge

Identification of residues defining phospholipid flippase substrate specificity of type IV P-type ATPases

Proceedings of the National Academy of Sciences
2012-02-07 | Journal article
DOI: 10.1073/pnas.1115725109
Part of ISSN: 0027-8424
Part of ISSN: 1091-6490
Source: Self-asserted source
Ryan Baldridge

Peer review (13 reviews for 7 publications/grants)

Review activity for ACS chemical biology. (4)
Review activity for Cell. (1)
Review activity for Molecular cell. (1)
Review activity for Nature communications (4)
Review activity for PloS one. (1)
Review activity for The Journal of cell biology. (1)
Review activity for Trends in cell biology. (1)
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