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Scopus Author ID: 7003522944

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Employment (4)

Sprouse Consulting LLC: Stonington, CT, US

2011 to present | Consultant / Owner
Employment
Source: Self-asserted source
Jeffrey Sprouse

Lundbeck Research USA Inc: Paramus, NJ, US

2007 to 2010 | Research Fellow (among others) (Neuroscience)
Employment
Source: Self-asserted source
Jeffrey Sprouse

Pfizer Global Research and Development: Groton, CT, US

1992 to 2007 | Associate Research Fellow (among others) (Neuroscience)
Employment
Source: Self-asserted source
Jeffrey Sprouse

Merrell Dow Research Institute: Cincinnati, OH, US

1989 to 1992 | Senior Research Pharmacologist (Neuroscience)
Employment
Source: Self-asserted source
Jeffrey Sprouse

Education and qualifications (4)

Yale University School of Medicine: New Haven, CT, US

1984 to 1989 | Postdoctoral Fellow (Psychiatry)
Education
Source: Self-asserted source
Jeffrey Sprouse

Weill Cornell Medical College: NY, NY, US

1978 to 1983 | PhD (Pharmacology)
Education
Source: Self-asserted source
Jeffrey Sprouse

Graduate School, Pennsylvania State University: PA, PA, US

1975 to 1977 | MS (Pharmacology)
Education
Source: Self-asserted source
Jeffrey Sprouse

University of Delaware: Newark, DE, US

1971 to 1975 | BA (Psychology / Chemistry)
Education
Source: Self-asserted source
Jeffrey Sprouse

Works (50 of 54)

Items per page:
Page 1 of 2

Small-molecule antagonists of melanopsin-mediated phototransduction

Nature Chemical Biology
2013 | Journal article
DOI: 10.1038/nchembio.1333
EID:

2-s2.0-84884532992
Contributors: Jones, K.A.; Hatori, M.; Mure, L.S.; Bramley, J.R.; Artymyshyn, R.; Hong, S.-P.; Marzabadi, M.; Zhong, H.; Sprouse, J.; Zhu, Q. et al.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

The effects of combining serotonin reuptake inhibition and 5-HT<inf>7</inf> receptor blockade on circadian rhythm regulation in rodents

Physiology and Behavior
2013 | Journal article
DOI: 10.1016/j.physbeh.2012.12.009
EID:

2-s2.0-84872394086
Contributors: Westrich, L.; Sprouse, J.; Sánchez, C.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Chronic treatment with a selective inhibitor of casein kinase I δ/ε yields cumulative phase delays in circadian rhythms

Psychopharmacology
2010 | Journal article
DOI: 10.1007/s00213-010-1860-5
EID:

2-s2.0-77954099912
Contributors: Sprouse, J.; Reynolds, L.; Kleiman, R.; Tate, B.; Swanson, T.A.; Pickard, G.E.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Circadian rhythm dysregulation in bipolar disorder

Current Opinion in Investigational Drugs
2010 | Journal article
EID:

2-s2.0-77954112466
Contributors: Westrich, L.; Sprouse, J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Serotonin and the Regulation of Mammalian Circadian Rhythms

Encyclopedia of Neuroscience
2010 | Book
DOI: 10.1016/B978-008045046-9.01607-7
EID:

2-s2.0-84882882926
Contributors: Sollars, P.J.; Pickard, G.E.; Sprouse, J.S.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Antagonism of 5-HT<inf>1A</inf> receptors uncovers an excitatory effect of SSRIs on 5-HT neuronal activity, an action probably mediated by 5-HT<inf>7</inf> receptors

Journal of Neurochemistry
2009 | Journal article
DOI: 10.1111/j.1471-4159.2008.05850.x
EID:

2-s2.0-59449083416
Contributors: Bosker, F.J.; Folgering, J.H.A.; Gladkevich, A.V.; Schmidt, A.; Van Der Hart, M.C.G.; Sprouse, J.; Den Boer, J.A.; Westerink, B.H.C.; Cremers, T.I.F.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Inhibition of casein kinase i ε/δ produces phase shifts in the circadian rhythms of Cynomolgus monkeys

Psychopharmacology
2009 | Journal article
DOI: 10.1007/s00213-009-1503-x
EID:

2-s2.0-67349160213
Contributors: Sprouse, J.; Reynolds, L.; Swanson, T.A.; Engwall, M.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

2-Aryloxy-4-alkylaminopyridines: Discovery of novel corticotropin-releasing factor 1 antagonists

Journal of Medicinal Chemistry
2008 | Journal article
DOI: 10.1021/jm070579c
EID:

2-s2.0-41649117497
Contributors: Chen, Y.L.; Obach, R.S.; Braselton, J.; Corman, M.L.; Forman, J.; Freeman, J.; Gallaschun, R.J.; Mansbach, R.; Schmidt, A.W.; Sprouse, J.S. et al.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

NAN-190 potentiates the circadian response to light and speeds re-entrainment to advanced light cycles

Neuroscience
2008 | Journal article
DOI: 10.1016/j.neuroscience.2008.04.054
EID:

2-s2.0-45849101678
Contributors: Kessler, E.J.; Sprouse, J.; Harrington, M.E.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists

Journal of Medicinal Chemistry
2008 | Journal article
DOI: 10.1021/jm070578k
EID:

2-s2.0-41649099236
Contributors: Chen, Y.L.; Braselton, J.; Forman, J.; Gallaschun, R.J.; Mansbach, R.; Schmidt, A.W.; Seeger, T.F.; Sprouse, J.S.; Tingley III, F.D.; Winston, E. et al.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

An inhibitor of casein kinase Iε induces phase delays in circadian rhythms under free-running and entrained conditions

Journal of Pharmacology and Experimental Therapeutics
2007 | Journal article
DOI: 10.1124/jpet.107.122846
EID:

2-s2.0-34547111542
Contributors: Badura, L.; Swanson, T.; Adamowicz, W.; Adams, J.; Cianfrogna, J.; Fisher, K.; Holland, J.; Kleiman, R.; Nelson, F.; Reynolds, L. et al.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Fluoxetine Modulates the Circadian Biological Clock via Phase Advances of Suprachiasmatic Nucleus Neuronal Firing

Biological Psychiatry
2006 | Journal article
DOI: 10.1016/j.biopsych.2006.03.003
EID:

2-s2.0-33748770420
Contributors: Sprouse, J.; Braselton, J.; Reynolds, L.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Circadian rhythm phenotype of 5-HT7 receptor knockout mice: 5-HT and 8-OH-DPAT-induced phase advances of SCN neuronal firing

Journal of Biological Rhythms
2005 | Journal article
DOI: 10.1177/0748730404273432
EID:

2-s2.0-15244345538
Contributors: Sprouse, J.; Li, X.; Stock, J.; McNeish, J.; Reynolds, L.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Potential Targets for the Treatment of Depressive Disorders

Mood Disorders: Clinical Management and Research Issues
2005 | Book
DOI: 10.1002/0470094281.ch14
EID:

2-s2.0-84889430538
Contributors: Rollema, H.M.; Sprouse, J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

8-OH-DPAT as a 5-HT7 agonist: Phase shifts of the circadian biological clock through increases in cAMP production

Neuropharmacology
2004 | Journal article
DOI: 10.1016/j.neuropharm.2003.08.007
EID:

2-s2.0-0345550330
Contributors: Sprouse, J.; Reynolds, L.; Li, X.; Braselton, J.; Schmidt, A.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Novel 5-HT<inf>7</inf> receptor inverse agonists. Synthesis and molecular modeling of arylpiperazine- and 1,2,3,4-tetrahydroisoquinoline-based arylsulfonamides

Journal of Medicinal Chemistry
2004 | Journal article
DOI: 10.1021/jm049743b
EID:

2-s2.0-6044276744
Contributors: Vermeulen, E.S.; Van Smeden, M.; Schmidt, A.W.; Sprouse, J.S.; Wikström, H.V.; Grol, C.J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Pharmacological modulation of circadian rhythms: A new drug target in psychotherapeutics

Expert Opinion on Therapeutic Targets
2004 | Journal article
DOI: 10.1517/14728222.8.1.25
EID:

2-s2.0-1242352528
Contributors: Sprouse, J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Serotonin-induced phase advances of SCN neuronal firing in vitro: A possible role for 5-HT5A receptors?

Synapse
2004 | Journal article
DOI: 10.1002/syn.20070
EID:

2-s2.0-4744365749
Contributors: Sprouse, J.; Reynolds, L.; Braselton, J.; Schmidt, A.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Characterization of the 5-HT7 Receptor. Determination of the Pharmacophore for 5-HT7 Receptor Agonism and CoMFA-Based Modeling of the Agonist Binding Site

Journal of Medicinal Chemistry
2003 | Journal article
DOI: 10.1021/jm030826m
EID:

2-s2.0-0344550379
Contributors: Vermeulen, E.S.; Schmidt, A.W.; Sprouse, J.S.; Wikström, H.V.; Grol, C.J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Activation of postsynaptic 5-HT1Areceptors by fluoxetine despite the loss of firing-dependent serotonergic input: Electrophysiological and neurochemical studies

Synapse
2001 | Journal article
DOI: 10.1002/syn.1059
EID:

2-s2.0-0035008660
Contributors: Sprouse, J.; Braselton, J.; Reynolds, L.; Clarke, T.; Rollema, H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

5-HT(1A) agonist potential of pindolol: Electrophysiologic studies in the dorsal raphe nucleus and hippocampus

Biological Psychiatry
2000 | Journal article
DOI: 10.1016/S0006-3223(99)00322-4
EID:

2-s2.0-0034110625
Contributors: Sprouse, J.; Braselton, J.; Reynolds, L.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex

Biological Psychiatry
2000 | Journal article
DOI: 10.1016/S0006-3223(00)00850-7
EID:

2-s2.0-0034254353
Contributors: Rollema, H.; Lu, Y.; Schmidt, A.W.; Sprouse, J.S.; Zorn, S.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Comparison of the novel antipsychotic ziprasidone with clozapine and olanzapine: Inhibition of dorsal raphe cell firing and the role of 5-HT(1A) receptor activation

Neuropsychopharmacology
1999 | Journal article
DOI: 10.1016/S0893-133X(99)00057-3
EID:

2-s2.0-0032845187
Contributors: Sprouse, J.S.; Reynolds, L.S.; Braselton, J.P.; Rollema, H.; Zorn, S.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

5-HT(1A) agonist activity of pindolol: Reversal of the inhibitory effects on cell firing in the dorsal raphe nucleus but not in the hippocampus by WAY-100,635

Annals of the New York Academy of Sciences
1998 | Book
DOI: 10.1111/j.1749-6632.1998.tb10221.x
EID:

2-s2.0-0032216597
Contributors: Sprouse, J.; Braselton, J.; Reynolds, L.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Consequences of 5-HT re-uptake blockade on postsynaptic 5-HT(1A) receptor activation: An electrophysiological and neurochemical study in guinea pig dorsal raphe and hippocampus

Annals of the New York Academy of Sciences
1998 | Book
DOI: 10.1111/j.1749-6632.1998.tb10220.x
EID:

2-s2.0-0032447586
Contributors: Sprouse, J.; Braselton, J.; Reynolds, L.; Clarke, T.; Rollema, H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Do 5-HT(1B/1D) autoreceptors modualte dorsal raphe cel firing? In vivo electrophysiological studies in guinea pigs with GR127935

Neuropharmacology
1997 | Journal article
DOI: 10.1016/S0028-3908(97)00028-2
EID:

2-s2.0-0030610863
Contributors: Sprouse, J.; Reynolds, L.; Rollema, H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Combined administration of a 5-hydroxytryptamine (5-HT)(1D) antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo

Journal of Neurochemistry
1996 | Journal article
EID:

2-s2.0-0029823246
Contributors: Rollema, H.; Clarke, T.; Sprouse, J.S.; Schulz, D.W.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Comparison of the effects of sertraline and its metabolite desmethylsertraline on blockade of central 5-HT reuptake in vivo

Neuropsychopharmacology
1996 | Journal article
DOI: 10.1016/0893-133X(95)00112-Q
EID:

2-s2.0-0029936825
Contributors: Sprouse, J.; Clarke, T.; Reynolds, L.; Heym, J.; Rollema, H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

CP-154,526: A potent and selective nonpeptide antagonist of corticotropin releasing factor receptors

Proceedings of the National Academy of Sciences of the United States of America
1996 | Journal article
DOI: 10.1073/pnas.93.19.10477
EID:

2-s2.0-0013522651
Contributors: Schulz, D.W.; Mansbach, R.S.; Sprouse, J.; Braselton, J.P.; Collins, J.; Corman, M.; Dunaiskis, A.; Faraci, S.; Schmidt, A.W.; Seeger, T. et al.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Innovative therapeutic actions by targeting serotonin 1a receptors selectively

International Review of Psychiatry
1995 | Journal article
DOI: 10.3109/09540269509022971
EID:

2-s2.0-0029032947
Contributors: Sprouse, J.S.; Wilkinson, L.O.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Electrophysiological evidence that desmethylsertraline is inactive at blocking central 5-HT uptake in vivo

European Neuropsychopharmacology
1994 | Journal article
EID:

2-s2.0-43949157125
Contributors: Sprouse, J.; Reynolds, L.; Heym, J.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity

Biochemical Pharmacology
1994 | Journal article
DOI: 10.1016/0006-2952(94)90576-2
EID:

2-s2.0-0028020419
Contributors: Iyer, R.N.; Sprouse, J.S.; Aghajanian, G.K.; Roth, R.H.; Bradberry, C.W.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Apparent regional differences in 5-HT1A binding may reflect [3H]8-OH-DPAT labeling of serotonin uptake sites

Brain Research
1993 | Journal article
DOI: 10.1016/0006-8993(93)90629-2
EID:

2-s2.0-0027162789
Contributors: Sprouse, J.S.; McCarty, D.R.; Dudley, M.W.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements

Journal of Neuroscience Methods
1991 | Journal article
DOI: 10.1016/0165-0270(91)90141-L
EID:

2-s2.0-0025967640
Contributors: Bradberry, C.W.; Sprouse, J.S.; Sheldon, P.W.; Aghajanian, G.K.; Roth, R.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Inhibition of dorsal raphe cell firing by MDL 73005EF, a novel 5-HT1A receptor ligand

European Journal of Pharmacology
1991 | Journal article
DOI: 10.1016/0014-2999(91)90340-V
EID:

2-s2.0-0025783402
Contributors: Sprouse, J.S.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release

Advances in Experimental Medicine and Biology
1991 | Journal article
EID:

2-s2.0-0026094505
Contributors: Bradberry, C.W.; Sprouse, J.S.; Aghajanian, G.K.; Roth, R.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

3,4-methylenedioxymethamphetamine (MDMA)-induced release of endogenous serotonin from the rat dorsal raphe nucleus in vitro: Effects of fluoxetine and tryptophan

Neurochemistry International
1990 | Journal article
DOI: 10.1016/0197-0186(90)90037-T
EID:

2-s2.0-0025185361
Contributors: Bradberry, C.W.; Sprouse, J.S.; Aghajanian, G.K.; Roth, R.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

3,4-methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan

European Journal of Pharmacology
1990 | Journal article
DOI: 10.1016/0014-2999(90)90110-R
EID:

2-s2.0-0025255548
Contributors: Sprouse, J.S.; Bradberry, C.W.; Roth, R.H.; Aghajanian, G.K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Electrophysiology of the Central Serotonin System: Receptor Subtypes and Transducer Mechanisms

Annals of the New York Academy of Sciences
1990 | Book
DOI: 10.1111/j.1749-6632.1990.tb16875.x
EID:

2-s2.0-0025606874
Contributors: AGHAJANIAN, G.K.; SPROUSE, J.S.; SHELDON, P.; RASMUSSEN, K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

MDMA (3,4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin

European Journal of Pharmacology
1989 | Journal article
DOI: 10.1016/0014-2999(89)90446-9
EID:

2-s2.0-0024449871
Contributors: Sprouse, J.S.; Bradberry, C.W.; Roth, R.H.; Aghajanian, G.K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: A comparative study with dorsal raphe neurons

Neuropharmacology
1988 | Journal article
DOI: 10.1016/0028-3908(88)90079-2
EID:

2-s2.0-0023948326
Contributors: Sprouse, J.S.; Aghajanian, G.K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Electrophysiological responses of serotoninergic dorsal raphe neurons to 5‐HT<inf>1A</inf> and 5‐HT<inf>1B</inf> agonists

Synapse
1987 | Journal article
DOI: 10.1002/syn.890010103
EID:

2-s2.0-0023165062
Contributors: Sprouse, J.S.; Aghajanian, G.K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists

European Journal of Pharmacology
1986 | Journal article
DOI: 10.1016/0014-2999(86)90782-X
EID:

2-s2.0-0022491475
Contributors: Sprouse, J.S.; Aghajanian, G.K.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Measurement of Fasciculations as Motor Nerve Ending Discharges in the Rat: A Dose Related Effect of Neostigmine (42014)

Proceedings of the Society for Experimental Biology and Medicine
1985 | Journal article
DOI: 10.3181/00379727-178-42014
EID:

2-s2.0-0021927349
Contributors: Sprouse, J.S.; Baker, T.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Pharmacologic excitability of rat motor nerve endings: The effect of adrenalectomy on neostigmine-induced fasciculations

Journal of Pharmacology and Experimental Therapeutics
1985 | Journal article
EID:

2-s2.0-0022404521
Contributors: Sprouse, J.S.; Baker, T.; Riker Jr., W.F.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Differential effects of mineralo- and glucocorticoids on mammalian motor nerve terminals

Federation Proceedings
1982 | Journal article
EID:

2-s2.0-0019967029
Contributors: Sprouse, J.; Baker, T.; Riker, W.F.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Effect of coadministration of procainamide and isoniazid on each other’s acetylation pathway

Pharmacology
1979 | Journal article
DOI: 10.1159/000137227
EID:

2-s2.0-0018409069
Contributors: Schneck, D.W.; Sprouse, J.S.; Shiroff, R.A.; Vary, J.E.; Dewitt, F.O.; Hayes, A.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

Plasma levels of free and acid-labile hydralazine: Effects of multiple dosing and of procainamide

Clinical Pharmacology and Therapeutics
1978 | Journal article
EID:

2-s2.0-0018215603
Contributors: Schneck, D.W.; Sprouse, J.S.; Miller, K.; Vary, J.E.; DeWitt, F.O.; Hayes Jr., A.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

The effect of hydralazine and other drugs on the kinetics of procainamide acetylation by rat liver and kidney N acetyltransferase

Journal of Pharmacology and Experimental Therapeutics
1978 | Journal article
EID:

2-s2.0-0018137317
Contributors: Schneck, D.W.; Sprouse, J.S.; Shiroff, R.A.; Hayes Jr., A.H.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier

The effect of hydralazine on procainamide acetylation in normal subjects

Clinical Pharmacology and Therapeutics
1978 | Journal article
EID:

2-s2.0-0017797728
Contributors: Sprouse, J.S.; Schneck, D.W.; Shiroff, R.
Source: Self-asserted source
Jeffrey Sprouse via Scopus - Elsevier
Items per page:
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