Erico Tosoni Costa (0000-0001-7413-4675)

Personal information

Biography

Bachelor in Biological Sciences from the University of São Paulo (USP, 2000, São Paulo, Brazil);
Ph.D. in Biochemistry and Molecular Biology from the Institute of Chemistry (USP, 2005, São Paulo, Brazil);
Postdoctoral fellow in Molecular Biology and Genetics of Cancer at the Ludwig Institute for Cancer Research (ILPC, located at AC Camargo Hospital, São Paulo, Brazil) (2006-2009);
Visiting researcher at the Ludwig Institute for Cancer Research & University of California (San Diego, USA) (2011).
Assistant Researcher in the Molecular Biology and Genomics group at ILPC (2009 - 2016, São Paulo, Brazil);
Senior Researcher at the Institute of Education and Research of the Hospital Sírio-Libanês (IEP-HSL) with the Molecular Oncology Center (MOC), São Paulo, Brazil.
Recent studies range from basic research with tumor cell cultures to preclinical screenings using fish (zebrafish) and mouse models.

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Hospital Sirio-Libanes: Sao Paulo, Sao Paulo, BR

2016-01-01 to present | Principal Investigator (Instituto de Ensino e Pesquisa)

Employment

Erico Tosoni Costa

https://orcid.org/0000-0001-7413-4675

Personal information

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Biography

Activities

Employment (1)

Hospital Sirio-Libanes: Sao Paulo, Sao Paulo, BR

Education and qualifications (3)

Ludwig Institute For Cancer Research: Sao Paulo, BR

University of Sao Paulo: São Paulo, BR

Universidade de São Paulo: São Paulo, São Paulo, BR

Works (32)

Basic Concepts of Carcinogenesis and Immunopathology

Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors

A novel program of infiltrative control in astrocytomas: ADAM23 depletion promotes cell invasion by activating ?-Secretase complex

l-carvone decreases breast cancer cells adhesion, migration, and invasion by suppressing FAK activation

Review of anticancer activity of monoterpenoids: Geraniol, nerol, geranial and neral

PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state

Antitumoral activity of liraglutide, a new DNMT inhibitor in breast cancer cells in vitro and in vivo

FRC-QE: a robust and comparable 3D microscopy image quality metric for cleared organoids

A Key Pathway to Cancer Resilience: The Role of Autophagy in Glioblastomas

Metformin as an Alternative Radiosensitizing Agent to 5-Fluorouracil During Neoadjuvant Treatment for Rectal Cancer

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

METFORMIN AS AN ALTERNATIVE TO 5FU AS RADIOSENSITIZER FOR RECTAL CANCER MANAGEMENT - RESULTS OF IN VITRO AND IN VIVO TREATMENT OF COLORECTAL CANCER CELL LINES

NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients

ADAM23 effects in proliferative and invasive phenotype of glioblastoma cells

Beyond the Proteolytic Activity: Examining the Functional Relevance of the Ancillary Domains Using Tri-Dimensional (3D) Spheroid Invasion Assay

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity

Membrane damage by betulinic acid provides insights into cellular aging

Inhibition of the RhoA GTPase activity increases sensitivity of melanoma cells to UV radiation effects

Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals

Parallel damage in mitochondrial and lysosomal compartments promotes efficient cell death with autophagy: The case of the pentacyclic triterpenoids

Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines

Intratumoral Societies - Subpopulations of Tumor Cells Expressing Different Levels of ADAM23 Seems Responsible for Different Aspects of Malignancy

Targeting MAGE-C1/CT7 expression increases cell sensitivity to the proteasome inhibitor bortezomib in multiple myeloma cell lines

<i>MAGE-C1/CT7</i> Inhibition Increases Myeloma Cell Line Sensitivity to Bortezomib-Induced Apoptosis: New Target for Myeloma Therapy?

ADAM23 splicing isoforms: distinct roles on the modulation of avb3 integrin activity

The functional role of ADAM23 on SKMel-37 melanoma cells

ADAM23 negatively modulates α<inf>v</inf>β<inf>3</inf>integrin activation during metastasis

Fibroblast growth factor 2 restrains Ras-driven proliferation of malignant cells by triggering RhoA-mediated senescence

c-Ki-ras oncogene amplification and FGF2 signaling pathways in the mouse Y1 adrenocortical cell line

c-Ki-ras oncogene amplification and FGF2 signaling pathways in the mouse Y1 adrenocortical cell line

Molecular mechanisms of cell cycle control in the mouse Y1 adrenal cell line

Role of ERK/MAP kinase in mitogenic interaction between ACTH and FGF2 in mouse Y1 adrenocortical tumor cells