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Employment (1)

University of Cologne: Cologne, DE

2010-05-01 to present | Professor (Institute for Genetics)
Employment
Source: Self-asserted source
Niels Gehring

Professional activities (1)

RNA Society: Bethesda, Maryland, US

Membership
Source: Self-asserted source
Niels Gehring

Works (22)

Modulation of UPF1 catalytic activity upon interaction of SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense mediated-mRNA decay

Nucleic Acids Research
2024-11-27 | Journal article
Contributors: Megha Mallick; Volker Boehm; Guangpu Xue; Mark Blackstone; Niels H Gehring; Sutapa Chakrabarti
Source: check_circle
Crossref

NMDtxDB: data-driven identification and annotation of human NMD target transcripts

RNA
2024-10 | Journal article
Contributors: Thiago Britto-Borges; Niels H. Gehring; Volker Boehm; Christoph Dieterich
Source: check_circle
Crossref

Functional implications of the interaction of the SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense-mediated mRNA decay

2024-07-16 | Preprint
Contributors: Megha Mallick; Volker Boehm; Guangpu Xue; Mark Blackstone; Niels H. Gehring; Sutapa Chakrabarti
Source: check_circle
Crossref

SMG1:SMG8:SMG9-complex integrity maintains robustness of nonsense-mediated mRNA decay

2024-04-15 | Preprint
Contributors: Sabrina Kueckelmann; Sophie Theunissen; Jan-Wilm Lackmann; Marek Franitza; Kerstin Becker; Volker Boehm; Niels H. Gehring
Source: check_circle
Crossref

NMDtxDB: Data-driven identification and annotation of human NMD target transcripts

2024-02-02 | Preprint
Contributors: Thiago Britto-Borges; Niels Gehring; Volker Boehm; Christoph Dieterich
Source: check_circle
Crossref

A two-step mitochondrial import pathway couples the disulfide relay with matrix complex I biogenesis

Journal of Cell Biology
2023-07-03 | Journal article
Contributors: Esra Peker; Konstantin Weiss; Jiyao Song; Christine Zarges; Sarah Gerlich; Volker Boehm; Aleksandra Trifunovic; Thomas Langer; Niels H. Gehring; Thomas Becker et al.
Source: check_circle
Crossref

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance

Nucleic Acids Research
2022-06-10 | Journal article
Contributors: Lena P Schlautmann; Jan-Wilm Lackmann; Janine Altmüller; Christoph Dieterich; Volker Boehm; Niels H Gehring
Source: check_circle
Crossref

Human UPF3A and UPF3B enable fault‐tolerant activation of nonsense‐mediated mRNA decay

The EMBO Journal
2022-05-16 | Journal article
Contributors: Damaris Wallmeroth; Jan‐Wilm Lackmann; Sabrina Kueckelmann; Janine Altmüller; Christoph Dieterich; Volker Boehm; Niels H Gehring
Source: check_circle
Crossref

Baltica: integrated splice junction usage analysis

2021-12-23 | Preprint
Contributors: Thiago Britto-Borges; Volker Boehm; Niels H. Gehring; Christoph Dieterich
Source: check_circle
Crossref

Exon junction complex-associated multi-adapter RNPS1 nucleates splicing regulatory complexes to maintain transcriptome surveillance

2021-08-20 | Other
Contributors: Lena P. Schlautmann; Volker Boehm; Jan-Wilm Lackmann; Janine Altmüller; Christoph Dieterich; Niels H. Gehring
Source: check_circle
Crossref

UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells

2021-07-07 | Preprint
Contributors: Damaris Wallmeroth; Volker Boehm; Jan-Wilm Lackmann; Janine Altmüller; Christoph Dieterich; Niels H. Gehring
Source: check_circle
Crossref

SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity

Nature Communications
2021-06-25 | Journal article
Contributors: Volker Boehm; Sabrina Kueckelmann; Jennifer V. Gerbracht; Sebastian Kallabis; Thiago Britto-Borges; Janine Altmüller; Marcus Krüger; Christoph Dieterich; Niels H. Gehring
Source: check_circle
Crossref

Ecd promotes U5 snRNP maturation and Prp8 stability

Nucleic Acids Research
2021-02-22 | Journal article
Contributors: Steffen Erkelenz; Dimitrije Stanković; Juliane Mundorf; Tina Bresser; Ann-Katrin Claudius; Volker Boehm; Niels H Gehring; Mirka Uhlirova
Source: check_circle
Crossref

Nonsense-mediated mRNA decay relies on “two-factor authentication” by SMG5-SMG7

2020-07-07 | Preprint
Contributors: Volker Boehm; Sabrina Kueckelmann; Jennifer V. Gerbracht; Thiago Britto-Borges; Janine Altmüller; Christoph Dieterich; Niels H. Gehring
Source: check_circle
Crossref

A Day in the Life of the Exon Junction Complex

Biomolecules
2020-06-05 | Journal article
Contributors: Lena P. Schlautmann; Niels H. Gehring
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain

Nature Communications
2019-08-15 | Journal article
Contributors: Annie M. Sriramachandran; Katrin Meyer-Teschendorf; Stefan Pabst; Helle D. Ulrich; Niels H. Gehring; Kay Hofmann; Gerrit J. K. Praefcke; R. Jürgen Dohmen
Source: check_circle
Crossref

Detection and quantification of RNA decay intermediates using XRN1-resistant reporter transcripts

Nature Protocols
2019-05-24 | Journal article
Contributors: Franka Voigt; Jennifer V. Gerbracht; Volker Boehm; Ivana Horvathova; Jan Eglinger; Jeffrey A. Chao; Niels H. Gehring
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Crossref

The exon junction complex: structural insights into a faithful companion of mammalian mRNPs

Biochemical Society Transactions
2018-02-19 | Journal article
Contributors: Jennifer V. Gerbracht; Niels H. Gehring
Source: check_circle
Crossref

Plasmid transfection influences the readout of nonsense-mediated mRNA decay reporter assays in human cells

Scientific Reports
2017-09-06 | Journal article
Contributors: Jennifer V. Gerbracht; Volker Boehm; Niels H. Gehring
Source: check_circle
Crossref

Transcript-specific characteristics determine the contribution of endo- and exonucleolytic decay pathways during the degradation of nonsense-mediated decay substrates

RNA
2017-08-01 | Journal article
Contributors: Franziska Ottens; Volker Boehm; Christopher R. Sibley; Jernej Ule; Niels H. Gehring
Source: check_circle
Crossref

Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences

Nature Communications
2016-12-05 | Journal article
Contributors: Volker Boehm; Jennifer V. Gerbracht; Marie-Charlotte Marx; Niels H. Gehring
Source: check_circle
Crossref

Mechanism, factors, and physiological role of nonsense-mediated mRNA decay

Cellular and Molecular Life Sciences
2015-12 | Journal article
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Crossref

Peer review (21 reviews for 15 publications/grants)

Review activity for BMC biology. (1)
Review activity for Cell death and differentiation. (1)
Review activity for Cell genomics. (1)
Review activity for Cell reports. (3)
Review activity for Communications biology. (1)
Review activity for Current opinion in genetics & development. (1)
Review activity for EMBO journal. (3)
Review activity for F1000Research. (1)
Review activity for Nature aging. (1)
Review activity for Nature cell biology (2)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
Review activity for Review Commons (1)
Review activity for Trends in biochemical sciences. (1)
Review activity for Trends in pharmacological sciences. (2)