Personal information

Activities

Employment (2)

University of Ljubljana: Ljubljana, SI

2021-04-01 to present | Postdoctoral Research Associate (Faculty of Pharmacy)
Employment
Source: Self-asserted source
ALEN KRAJNC

Actelion Pharmaceuticals Ltd: Allschwil, Basel-Landschaft, CH

2015-01-08 to 2016-07-31 | Trainee in Anti-Infectives (Synthetic medicinal chemistry) (DD Chemistry)
Employment
Source: Self-asserted source
ALEN KRAJNC

Education and qualifications (2)

University of Oxford: Oxford, Oxfordshire, GB

(Linacre College; Organic Chemistry)
Education
Source: check_circle
ORCID Integration at the University of Oxford

University of Nottingham: Nottingham, Nottingham, GB

2013-09-23 to 2017-07-18 | MSci Hons Medicinal and Biological Chemistry with an Assessed year in Industry (School of Chemistry)
Education
Source: Self-asserted source
ALEN KRAJNC

Works (11)

Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s)

Acta Pharmaceutica
2024-09-01 | Journal article
Contributors: Katarina Grabrijan; Nika Strašek Benedik; Alen Krajnc; Krištof Bozovičar; Damijan Knez; Matic Proj; Irena Zdovc; Izidor Sosič; Carlos Contreras-Martel; Andréa Dessen et al.
Source: check_circle
Crossref

Conjugates of monocyclic β-lactams and siderophore mimetics: a patent evaluation (WO2023023393)

Expert Opinion on Therapeutic Patents
2023-08-03 | Journal article
Contributors: Alen Krajnc; Stanislav Gobec
Source: check_circle
Crossref

Reaction of nitrocefin with two serines of Pseudomonas aeruginosa penicillin-binding-protein 3

2022-06-17 | Preprint
Contributors: Hector Newman; Dom Bellini; Alen Krajnc; Anthony Tumber; Julie Tod; Adrian Lloyd; Christopher Schofield; Christopher Dowson
Source: check_circle
Crossref

High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes

Journal of Medicinal Chemistry
2021-08-12 | Journal article
Contributors: Hector Newman; Alen Krajnc; Dom Bellini; Charles J. Eyermann; Grant A. Boyle; Neil G. Paterson; Katherine E. McAuley; Robert Lesniak; Mukesh Gangar; Frank von Delft et al.
Source: check_circle
Crossref

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat

ChemMedChem
2021-07-06 | Journal article
Contributors: William D. Figg, Jr; Michael A. McDonough; Rasheduzzaman Chowdhury; Yu Nakashima; Zhihong Zhang; James P. Holt‐Martyn; Alen Krajnc; Christopher J. Schofield
Source: check_circle
Crossref

Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition

RSC Medicinal Chemistry
2020 | Journal article
Contributors: Catherine L. Tooke; Philip Hinchliffe; Alen Krajnc; Adrian J. Mulholland; Jürgen Brem; Christopher J. Schofield; James Spencer
Source: check_circle
Crossref

The impact of COVID‐19 on the cancer care of adolescents and young adults and their well‐being: Results from an online survey conducted in the early stages of the pandemic

Cancer
2020-10 | Journal article
Contributors: Urška Košir; Maria Loades; Jennifer Wild; Milan Wiedemann; Alen Krajnc; Sanja Roškar; Lucy Bowes
Source: check_circle
Crossref

Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

Biomolecules
2020-06-12 | Journal article
Contributors: Pauline A. Lang; Anete Parkova; Thomas M. Leissing; Karina Calvopiña; Ricky Cain; Alen Krajnc; Tharindi D. Panduwawala; Jules Philippe; Colin W. G. Fishwick; Peteris Trapencieris et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Broad Spectrum β-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate

ACS Infectious Diseases
2020-06-12 | Journal article
Contributors: Anete Parkova; Anka Lucic; Alen Krajnc; Jürgen Brem; Karina Calvopiña; Gareth W. Langley; Michael A. McDonough; Peteris Trapencieris; Christopher J. Schofield
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

Journal of Medicinal Chemistry
2019-09-26 | Journal article
Contributors: Alen Krajnc; Jürgen Brem; Philip Hinchliffe; Karina Calvopiña; Tharindi D. Panduwawala; Pauline A. Lang; Jos J. A. G. Kamps; Jonathan M. Tyrrell; Emma Widlake; Benjamin G. Saward et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Will morphing boron-based inhibitors beat the β-lactamases?

Current Opinion in Chemical Biology
2019-06 | Journal article
Contributors: Alen Krajnc; Pauline A Lang; Tharindi D Panduwawala; Jürgen Brem; Christopher J Schofield
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Peer review (2 reviews for 2 publications/grants)

Review activity for ChemBioChem. (1)
Review activity for Chemistry & biodiversity. (1)