Personal information

Verified email addresses

Verified email domains

Immunology, Infectious Diseases, Molecular and cellular Biology, Serodiagnostic assays,, Malaria, COVID-19, field-based studies, multidisciplinarity, Immune correlates of protection, Humoral and cellular immunity
Senegal

Biography

As Senior and Expert Research Scientist (Research Director) at Institut Pasteur since 2013, I bring extensive expertise in molecular and cellular biology, immunology, and infectious diseases, with a specialized focus on malaria and host immune responses. My carrier began with a University Degree of Technology in Biological Analyses (DUT, ENSUT, Dakar-Senegal) in 1994, followed by a PhD in Molecular and Cellular Biology and Immunology from Joseph FOURIER University, Grenoble, France, in 2001. This robust academic foundation propelled me into a pioneering research career at Institut Pasteur, where I broke new ground in host-parasite interactions during malaria.

Over the last two decades, as PI and co-PI of multiple high-impact multidisciplinary research projects, I have played a world-leading role in malaria research. My contributions span (1) advanced phenotypic, functional, structural, and immunological characterizations of receptor-ligand interactions driving P. falciparum cytoadherence, (2) innovative field-based malaria studies, and (3) the development of cutting-edge serological tools for monitoring malaria control strategies and elucidating host-parasite dynamics during Plasmodium falciparum and P. vivax infections. These efforts have significantly influenced malaria control and elimination strategies.

Following temporary career interruptions due to family obligations (2005-2006 & 2010-2011), I returned to lead groundbreaking research at Institut Pasteur in Paris, successfully reintegrating as a key member of the research staff. My commitment to leveraging scientific expertise for public health impact led me to join the Institut Pasteur International Network in 2013, where I assumed leadership of the Immunology of Infectious Diseases Unit at Institut Pasteur de Madagascar.

In Madagascar (2013-2019), I established an advanced immunological research platform, driving transformative research programs to address pressing public health challenges, including stunting, malaria, taeniasis/cysticercosis, leptospirosis, and plague. I led the development of innovative serological and molecular diagnostic tools, significantly enhancing disease surveillance and public health interventions. My strategic vision extended to capacity building, where I championed mentorship and training programs for emerging scientists, particularly in immunology and malaria, fostering sustainable scientific growth in low-resource settings. I also spearheaded the acquisition of a state-of-the-art microbiology mobile laboratory, revolutionizing epidemic-prone disease surveillance and public health responses in remote areas.

My exceptional leadership and commitment to advancing global health were recognized in 2019 when I was named among the 200 Francophone Women Leaders in Global Health worldwide. This honor reflects my unwavering dedication to research, public health, and capacity building to improve health outcomes in underserved communities.

Since September 1, 2019, I have served as Head of the Immunophysiopathology and Infectious Diseases Department at Institut Pasteur de Dakar, Senegal. In this role, I lead a high-performing, multidisciplinary team driving cutting-edge research on malaria and COVID-19. I am currently leading the CEPI Reference Laboratory at IPD, supporting vaccine validation during clinical trials, thereby accelerating the development of safe and effective vaccines for global health security. I strategically oversee immunological and single-cell analysis platforms, pioneering studies that integrate local pathogen genomic surveillance with immunological data to accelerate diagnostics and vaccine discovery. My work continues to influence global health policies and advance public health strategies across Africa.

Activities

Employment (4)

Institut Pasteur de Dakar: Dakar, Dakar, SN

2019-09-01 to present | Head of Research Department (Immuphysiopathology and Infectious Diseases )
Employment
Source: Self-asserted source
VIGAN-WOMAS Ines

Institut Pasteur: Paris, Île-de-France, FR

2006-09-01 to present | Research Director (Pasteur Network )
Employment
Source: Self-asserted source
VIGAN-WOMAS Ines

Institut Pasteur de Madagascar: Antananarivo, Océan Indien, MG

2013-10-01 to 2019-08-31 | Head of Unit (Immunology of Infectious Diseases)
Employment
Source: Self-asserted source
VIGAN-WOMAS Ines

Institut Pasteur: Paris, Île-de-France, FR

2001-11-01 to 2006-07-31 | Postdoctoral Fellow (Unité d'Immunologie Moléculaire des Parasites )
Employment
Source: Self-asserted source
VIGAN-WOMAS Ines

Education and qualifications (6)

Université de la Réunion: Saint-Denis , RE

2016-01-26 to present | Habilitation à Diriger les Recherches (HDR) / Authorization to conduct Research Programs (Pôle Recherche - UFR Santé (Immunologie/Parasitologie))
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Université de Grenoble I: Grenoble, Rhône-Alpes, FR

1998-01-01 to 2001-09-24 | PhD (Cellular and Molecular Biology / Immunology and Infectious Diseases, )
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Université de Grenoble I: Grenoble, Rhône-Alpes, FR

1995-09-01 to 1997-07-31 | Master of Science (MSc) (Molecular and Cellular Biology, Immunology)
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Université Grenoble Alpes: Grenoble, Rhône-Alpes, FR

1994-09-01 to 1995-06-30 | Bachelor of Science (BSc) (Cellular Biology and Physiology)
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Université Cheikh Anta Diop: Dakar, Dakar, SN

1992-09-01 to 1994-07-31 | Diploma of Higher Education (Ecole National Supérieur de Technologie (ENSUT))
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Institution Notre-Dame de Dakar: Dakar , SN

1991-09-01 to 1992-07-31 | High School Diploma
Education
Source: Self-asserted source
VIGAN-WOMAS Ines

Funding (20)

CEPI-CLN-IPD: Coalition for Epidemic Preparedness and Innovations (CEPI) Reference Laboratory

2023-06 to 2028-12 | Grant
Coalition for Epidemic Preparedness Innovations (Oslo, Oslo, NO)
Source: Self-asserted source
VIGAN-WOMAS Ines

PIU-IMMUNO: : Deciphering adaptative immune responses to emerging and epidemic-prone infectious diseases (COVID-19 – Dengue – Disease X), IP Dakar, IP Cambodia & IP Madagascar.

2023-06 to 2028-12 | Grant
Pasteur Network / IP Dakar (Dakar, SN)
GRANT_NUMBER:

PIU-Immuno

Source: Self-asserted source
VIGAN-WOMAS Ines

Integrated SeroSurveillance of pathogens in Senegal

2023-06 to 2025-12 | Grant
Gates Foundation (Seattle, Washington, US)
Part of GRANT_NUMBER:

INV-050589

Source: Self-asserted source
VIGAN-WOMAS Ines

RO1VAC - Evaluating the Functional Impact of Genetic Diversity on Malaria Vaccine Candidates

2022-09 to 2026-12 | Grant
National Institutes of Health (Bethesda, Maryland, US)
Part of GRANT_NUMBER:

R01AI168238

Source: Self-asserted source
VIGAN-WOMAS Ines

VE-SEN-SARI: Evaluation of vaccine effectiveness (VE) against SARS-CoV-2 infections through surveillance activities for severe acute respiratory infections in Senega

2022-02 to 2023-12 | Grant
World Health Organization (Geneva, CH)
Source: Self-asserted source
VIGAN-WOMAS Ines

EFA-SEN - Etiology and risk factors associated with non-Plasmodial acute febrile illness (AFI) in the Sentinel Syndromic Surveillance Network of Senegal (4S Network)

2022-01 to 2025-12 | Grant
Centers for Disease Control and Prevention (Atlanta, Georgia, US)
Part of GRANT_NUMBER:

# RFA-GH-19-003

Source: Self-asserted source
VIGAN-WOMAS Ines

MultiSeroSurV - Algorithms and multiplex assays for integrated serological surveillance of malaria and neglected tropical diseases

2022-01 to 2025-12 | Grant
European Research Council (Brussels, Brussels Capital, BE)
Part of GRANT_NUMBER:

ERC starting Grant/ #852373

Source: Self-asserted source
VIGAN-WOMAS Ines

GIISER-SEnegal: Accelerate the connection of local pathogen genomic surveillance and immunological data for vaccine development

2021-09 to 2024-08 | Grant
Gates Foundation (Seattle, Washington, US)
GRANT_NUMBER:

INV-030776

Source: Self-asserted source
VIGAN-WOMAS Ines

Action-PALU : Towards the elimination of malaria in Senegal: targeting the parasite reservoir and tracking antimalarial drug resistance

2021-06 to 2022-12 | Grant
Rotary International (USA, Paris/Versailles and Dakar-Senegal, Paris - Versailles , FR)
Source: Self-asserted source
VIGAN-WOMAS Ines

COV-PIM: Screening of T and B cellular immune responses against SARS-COV-2 virus peptides in patients with COVID-19 (Peptide mapping and ELISPOT)

2020-09 to 2022-06 | Contract
Institut Pasteur (France , FR)
Source: Self-asserted source
VIGAN-WOMAS Ines

REPAIR: Institut Pasteur International Network Research program in Response to Coronavirus in Africa” (REPAIR): Multidisciplinary investigation of the COVID-19 pandemic in Africa.

2020-07 to 2022-12 | Contract
French Ministry of Foreign Affairs (MEAE) & Pasteur Institut (France, FR)
Source: Self-asserted source
VIGAN-WOMAS Ines

SeroSEN-SARS: Analysis of the spread of the SARS-CoV-2 virus in Senegal: Seroepidemiological study in blood donors and populations living in areas of low and high incidence of COVID-19

2020-06 to 2021-12 | Contract
Fondation SUEZ (France, FR)
Source: Self-asserted source
VIGAN-WOMAS Ines

SEN-COV et SEN-COV-FADJ: Assessment of the clinical forms and evolution of SARS-COV-2 infection in Senegal.

2020-04 to 2021-12 | Contract
Multi-Funding (FRANCE, FR)
Source: Self-asserted source
VIGAN-WOMAS Ines

“Mucosal and systemic immune responses in children suffering from malnutrition and environmental enteropathy

2017-01 to 2019-12 | Grant
Institut Pasteur (Paris , FR)
GRANT_NUMBER:

PTR 08-16

Source: Self-asserted source
VIGAN-WOMAS Ines

Strengthen the Immunomonitoring Platform of Institut Pasteur de Madagascar

2016-04 to 2016-09 | Award
Institut Pasteur (Paris , FR)
GRANT_NUMBER:

Y-SCI14017

Source: Self-asserted source
VIGAN-WOMAS Ines

Beyond Artemisinin Resistance Associated to Plasmodium K13: towards insights on K13 biological function (Be-ARTR)

2015-10 to 2017-09 | Grant
Institut Pasteur (Pasris, FR)
GRANT_NUMBER:

PTR 535

Source: Self-asserted source
VIGAN-WOMAS Ines

Analysis of receptor-ligand interactions involved in host cell invasion by Plasmodium vivax merozoites: Building the rationale for a blood stage malaria vaccine

2014-10 to 2017-05 | Grant
Institut Pasteur (Paris, FR)
GRANT_NUMBER:

PTR 490

Source: Self-asserted source
VIGAN-WOMAS Ines

Characterization of new invasive pathways of Duffy-negative red blood cells or reticulocytes by Plasmodium vivax

2014-02 to 2016-01 | Grant
Institut Pasteur de Madagascar (Antan, Antananarivo, MG)
Source: Self-asserted source
VIGAN-WOMAS Ines

School-Based Malaria Survey - SBS” grant: Use of Serology to Validate Health Facility-Based Data for Prioritizing IRS in the Central Highlands of Madagascar

2013-11 to 2015-09 | Grant
United States Agency for International Development & President's Malaria Initiative (DC, DC, US)
GRANT_NUMBER:

AID-687-G-13-00003

Source: Self-asserted source
VIGAN-WOMAS Ines

Operational Evaluation of Integrated Malaria Control program

2013-05 to 2016-04 | Grant
Global Fund to Fight AIDS, Tuberculosis and Malaria (Geneva , CH)
GRANT_NUMBER:

12INI210

Source: Self-asserted source
VIGAN-WOMAS Ines