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Moderate protein intake percentage in mice for maintaining metabolic health during approach to old age

GeroScience
2023-04-28 | Journal article
Contributors: Yoshitaka Kondo; Hitoshi Aoki; Masato Masuda; Hiroki Nishi; Yoshihiro Noda; Fumihiko Hakuno; Shin-Ichiro Takahashi; Takuya Chiba; Akihito Ishigami
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Accuracy of Therapeutic Drug Monitoring of Teicoplanin at the Onset of Febrile Neutropenia

Medicina
2023-04-13 | Journal article
Contributors: Masaki Takigawa; Hiroyuki Tanaka; Junichi Suwa; Tomoya Obara; Yohei Maeda; Mamoru Sato; Yoshitomo Shimazaki; Toshihisa Onoda; Akihito Ishigami; Toshihiro Ishii
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Oxidative Stress Inhibits Endotoxin Tolerance and May Affect Periodontitis

Journal of Dental Research
2023-03 | Journal article
Contributors: T. Yamaguchi; Y. Yamamoto; K. Egashira; A. Sato; Y. Kondo; S. Saiki; M. Kimura; T. Chikazawa; Y. Yamamoto; A. Ishigami et al.
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Determination of tissue-specific interaction between vitamin C and vitamin E in vivo using senescence marker protein-30 knockout mice as a vitamin C synthesis deficiency model

British Journal of Nutrition
2022-09-28 | Journal article
Contributors: Ayami Sato; Yuka Takino; Tomohiro Yano; Koji Fukui; Akihito Ishigami
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Vitamin C Is Essential for the Maintenance of Skeletal Muscle Functions

Biology
2022-06-23 | Journal article
Contributors: Shoko Takisawa; Yuka Takino; Jaewon Lee; Shuichi Machida; Akihito Ishigami
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Compartmentalized citrullination in Muller glial endfeet during retinal degeneration

Proceedings of the National Academy of Sciences
2022-03 | Journal article
Contributors: Sarah I. Palko; Nicholas J. Saba; Elias Mullane; Benjamin D. Nicholas; Yosuke Nagasaka; Jayakrishna Ambati; Bradley D. Gelfand; Akihito Ishigami; Paola Bargagna-Mohan; Royce Mohan
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Reduced Plasma Ascorbate and Increased Proportion of Dehydroascorbic Acid Levels in Patients Undergoing Hemodialysis

Life
2021-09-28 | Journal article
Contributors: Yuta Doshida; Mitsuyo Itabashi; Takashi Takei; Yuka Takino; Ayami Sato; Wako Yumura; Naoki Maruyama; Akihito Ishigami
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Specific Increase in Joint Neutrophil Extracellular Traps and Its Relation to Interleukin 6 in Autoimmune Arthritis

International Journal of Molecular Sciences
2021-07-16 | Journal article
Contributors: Ayako Ohyama; Atsumu Osada; Hoshimi Kawaguchi; Izumi Kurata; Taihei Nishiyama; Tamaki Iwai; Akihito Ishigami; Yuya Kondo; Hiroto Tsuboi; Takayuki Sumida et al.
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Neuroprotective and Anti-Inflammatory Effects of Evernic Acid in an MPTP-Induced Parkinson’s Disease Model

International Journal of Molecular Sciences
2021-02-20 | Journal article
Contributors: Seulah Lee; Yeon Ji Suh; Seonguk Yang; Dong Geun Hong; Akihito Ishigami; Hangun Kim; Jae-Seoun Hur; Seung-Cheol Chang; Jaewon Lee
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Radiation-induced gastrointestinal syndrome is exacerbated in vitamin C–insufficient SMP30/GNL knockout mice

Nutrition
2021-01 | Journal article
Contributors: Reina Saga; Takahiro Uchida; Yuka Takino; Yoshitaka Kondo; Hiroaki Kobayashi; Manabu Kinoshita; Daizoh Saitoh; Akihito Ishigami; Makoto Makishima
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Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis

PLOS ONE
2020-11-25 | Journal article
Contributors: Yuta Doshida; Ezio Laconi; Haruka Sano; Sadahiro Iwabuchi; Toshiro Aigaki; Masayuki Yoshida; Shinichi Hashimoto; Akihito Ishigami
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Age-related dysfunction of p53-regulated phagocytic activity in macrophages

Biochemical and Biophysical Research Communications
2020-08 | Journal article
Contributors: Yohko Yamaguchi; Kohei Kaida; Yusuke Suenaga; Akihito Ishigami; Yoshiro Kobayashi; Kisaburo Nagata
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Evaluating extremely low plasma ascorbate levels and reduction of plasma ascorbate levels by dialysis in Japanese hemodialysis patients

2020-05-21 | Other
Contributors: Yuta Doshida; Mitsuyo Itabashi; Takashi Takei; Yuka Takino; Ayami Sato; Tomofumi Yatsu; Wako Yumura; Naoki Maruyama; Akihito Ishigami
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Dibutyl phthalate impairs neural progenitor cell proliferation and hippocampal neurogenesis

Food and Chemical Toxicology
2019-07 | Journal article
Contributors: Wonjong Lee; Jung-Hyun Cho; Yujeong Lee; Seulah Lee; Dae Hyun Kim; Sugyeong Ha; Yoshitaka Kondo; Akihito Ishigami; Hae Young Chung; Jaewon Lee
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Dietary ascorbic acid restriction in GNL/SMP30-knockout mice unveils the role of ascorbic acid in regulation of somatic and visceral pain sensitivity

Biochemical and Biophysical Research Communications
2019-04 | Journal article
Contributors: Maho Tsubota; Kenta Uebo; Koki Miki; Fumiko Sekiguchi; Akihiko Ishigami; Atsufumi Kawabata
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Vitamin C and vitamin E double-deficiency increased neuroinflammation and impaired conditioned fear memory

Archives of Biochemistry and Biophysics
2019-03 | Journal article
Contributors: Keita Takahashi; Shuichi Yanai; Shoko Takisawa; Nozomu Kono; Hiroyuki Arai; Yoichiro Nishida; Takanori Yokota; Shogo Endo; Akihito Ishigami
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Vitamin C deficiency causes muscle atrophy and a deterioration in physical performance

Scientific Reports
2019-03-20 | Journal article
Contributors: Shoko Takisawa; Tomoko Funakoshi; Tomofumi Yatsu; Kisaburo Nagata; Toshiro Aigaki; Shuichi Machida; Akihito Ishigami
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Reduced aqueous humour ascorbic-acid concentration in women with smaller anterior chamber depth

Scientific Reports
2019-01-23 | Journal article
Contributors: Sakae Ito; Toshimi Sairenchi; Takehisa Machida; Yuka Takino; Yoshitaka Kondo; Koichiro Mukai; Gen Kobashi; Akihito Ishigami; Tadashi Senoo
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Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage

Scientific Reports
2018-11-01 | Journal article
Contributors: Saki Kawashima; Tomoko Funakoshi; Yasunori Sato; Norikatsu Saito; Hajime Ohsawa; Katsumi Kurita; Kisaburo Nagata; Masayuki Yoshida; Akihito Ishigami
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The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells

International Journal of Molecular Sciences
2017-10 | Journal article
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Multidisciplinary Digital Publishing Institute
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Coffee consumption in aged mice increases energy production and decreased hepatic mTOR levels

Nutrition
2017-01 | Journal article
Contributors: Keita Takahashi; Shuichi Yanai; Kentaro Shimokado; Akihito Ishigami
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Acerola (Malpighia emarginata DC.) Juice Intake Suppresses UVB-Induced Skin Pigmentation in SMP30/GNL Knockout Hairless Mice

PLOS ONE
2017-01-23 | Journal article
Contributors: Yasunori Sato; Andrzej T Slominski; Eriko Uchida; Hitoshi Aoki; Takayuki Hanamura; Kenichi Nagamine; Hisanori Kato; Takeshi Koizumi; Akihito Ishigami
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Attenuated phagocytosis of secondary necrotic neutrophils by macrophages in aged and SMP30 knockout mice

Geriatrics & Gerontology International
2015-01 | Journal article
DOI:

10.1111/ggi.12436

Contributors: Rei Takahashi; Sayuri Totsuka; Akihito Ishigami; Yoshiro Kobayashi; Kisaburo Nagata
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High dietary intake of vitamin C suppresses age-related thymic atrophy and contributes to the maintenance of immune cells in vitamin C-deficient senescence marker protein-30 knockout mice

Br J Nutr
2015-01 | Journal article
DOI:

10.1017/s0007114514003857

Contributors: Ryusei Uchio; Yoshitaka Hirose; Shinji Murosaki; Yoshihiro Yamamoto; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Senescence marker protein-30/superoxide dismutase 1 double knockout mice exhibit increased oxidative stress and hepatic steatosis

FEBS Open Bio
2014 | Journal article
DOI:

10.1016/j.fob.2014.05.003

Contributors: Yoshitaka Kondo; Hirofumi Masutomi; Yoshihiro Noda; Yusuke Ozawa; Keita Takahashi; Setsuko Handa; Naoki Maruyama; Takahiko Shimizu; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Vitamin C and Physical Performance in the Elderly

Aging
2014 | Other
DOI:

10.1016/b978-0-12-405933-7.00012-3

Contributors: Kyoko Saito; Erika Hosoi; Akihito Ishigami; Tetsuji Yokoyama
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Akihito Ishigami via Crossref Metadata Search

Anti-inflammatory activity of SMP30 modulates NF-κB through protein tyrosine kinase/phosphatase balance

J Mol Med
2014-11 | Journal article
DOI:

10.1007/s00109-014-1219-1

Contributors: Kyung Jin Jung; Eun Kyeong Lee; Su Jin Kim; Chang Woo Song; Naoki Maruyama; Akihito Ishigami; Nam Deuk Kim; Dong-Soon Im; Byung Pal Yu; Hae Young Chung
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Akihito Ishigami via Crossref Metadata Search

Age-associated decrease of senescence marker protein-30/gluconolactonase in individual mouse liver cells: Immunohistochemistry and immunofluorescence

Geriatrics & Gerontology International
2014-10 | Journal article
DOI:

10.1111/ggi.12347

Contributors: Akihito Ishigami; Hirofumi Masutomi; Setsuko Handa; Naoki Maruyama
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Akihito Ishigami via Crossref Metadata Search

Potato Chip Intake Increases Ascorbic Acid Levels and Decreases Reactive Oxygen Species in SMP30/GNL Knockout Mouse Tissues

J. Agric. Food Chem.
2014-09 | Journal article
DOI:

10.1021/jf502587j

Contributors: Yoshitaka Kondo; Rui Sakuma; Megumi Ichisawa; Katsuyuki Ishihara; Misako Kubo; Setsuko Handa; Hiroyuki Mugita; Naoki Maruyama; Hidenori Koga; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Ascorbic acid deficiency affects genes for oxidation–reduction and lipid metabolism in livers from SMP30/GNL knockout mice

Biochimica et Biophysica Acta (BBA) - General Subjects
2014-07 | Journal article
DOI:

10.1016/j.bbagen.2014.03.019

Contributors: Keita Takahashi; Yuki Kishimoto; Tomokazu Konishi; Yasunori Fujita; Masafumi Ito; Kentaro Shimokado; Naoki Maruyama; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Senescence marker protein-30/gluconolactonase deficiency exacerbates diabetic nephropathy through tubular injury in a mouse model of type 1 diabetes

J Diabetes Invest
2014-07-07 | Journal article
DOI:

10.1111/jdi.12252

Contributors: Hiroshi Okada; Takafumi Senmaru; Michiaki Fukui; Yoshitaka Kondo; Akihito Ishigami; Naoki Maruyama; Hiroshi Obayashi; Masahiro Yamazaki; Naoto Nakamura; Goji Hasegawa
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Akihito Ishigami via Crossref Metadata Search

P43 Ascorbic acid deficiency augments hyperalgesia induced by hydrogen sulfide in mice

Nitric Oxide
2014-05 | Journal article
DOI:

10.1016/j.niox.2014.03.093

Contributors: Maho Tsubota; Kenta Uebo; Koki Miki; Fumiko Sekiguchi; Yoshitaka Kondo; Keita Takahashi; Hirofumi Masutomi; Akihito Ishigami; Atsufumi Kawabata
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Akihito Ishigami via Crossref Metadata Search

Age-related oxidant stress with senescence marker protein-30 deficiency plays a pivotal role in coronary artery spasm

Coronary Artery Disease
2013 | Journal article
DOI:

10.1097/mca.0b013e32835c8f96

Contributors: Yasuto Hoshino; Shinya Yamada; Shu-ichi Saitoh; Hirofumi Machii; Hiroyuki Mizukami; Makiko Miyata; Tomofumi Misaka; Akihito Ishigami; Yasuchika Takeishi
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Effects of Ascorbic Acid Deficiency on Protein and Lipid Oxidation in Livers from SMP30/GNL Knockout Mice

JNSV
2013 | Journal article
DOI:

10.3177/jnsv.59.489

Contributors: Akiko AMANO; Yasunori SATO; Yuki KISHIMOTO; Keita TAKAHASHI; Setsuko HANDA; Toshiro AIGAKI; Naoki MARUYAMA; Akihito ISHIGAMI
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Akihito Ishigami via Crossref Metadata Search

Exome sequencing of senescence-accelerated mice (SAM) reveals deleterious mutations in degenerative disease-causing genes

BMC Genomics
2013 | Journal article
DOI:

10.1186/1471-2164-14-248

Contributors: Kumpei Tanisawa; Eri Mikami; Noriyuki Fuku; Yoko Honda; Shuji Honda; Ikuro Ohsawa; Masafumi Ito; Shogo Endo; Kunio Ihara; Kinji Ohno et al.
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Akihito Ishigami via Crossref Metadata Search

Senescence Marker Protein 30 Has a Cardio-Protective Role in Doxorubicin-Induced Cardiac Dysfunction

PLoS ONE
2013 | Journal article
DOI:

10.1371/journal.pone.0079093

Contributors: Makiko Miyata; Satoshi Suzuki; Tomofumi Misaka; Tetsuro Shishido; Shu-ichi Saitoh; Akihito Ishigami; Isao Kubota; Yasuchika Takeishi; Rakesh Kukreja
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Akihito Ishigami via Crossref Metadata Search

Senescence Marker Protein-30/Gluconolactonase Expression in the Mouse Ovary during Gestation

Biol. Pharm. Bull.
2013 | Journal article
DOI:

10.1248/bpb.b13-00309

Contributors: Yayoi Kagami; Yoshitaka Kondo; Setsuko Handa; Naoki Maruyama; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Smad3 Deficiency Ameliorates Hepatic Fibrogenesis through the Expression of Senescence Marker Protein-30, an Antioxidant-Related Protein

IJMS
2013 | Journal article
DOI:

10.3390/ijms141223700

Contributors: Da-Hee Jeong; Meeyul Hwang; Jin-Kyu Park; Moon-Jung Goo; Il-Hwa Hong; Mi-Ran Ki; Akihito Ishigami; Ah-Young Kim; Eun-Mi Lee; Eun-Joo Lee et al.
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Akihito Ishigami via Crossref Metadata Search

SMP30/GNL ノックアウトマウスを用いたビタミン C 摂取が酸化ストレス防御系におよぼす影響

JJCAM
2013 | Journal article
DOI:

10.1625/jcam.10.63

Contributors: Hiroshi MARUOKA; Yuki KISHIMOTO; Akihito ISHIGAMI
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Akihito Ishigami via Crossref Metadata Search

Coronary Artery Spasm Related to Thiol Oxidation and Senescence Marker Protein-30 in Aging

Antioxidants & Redox Signaling
2013-10 | Journal article
DOI:

10.1089/ars.2012.4903

Contributors: Shinya Yamada; Shu-ichi Saitoh; Hirofumi Machii; Hiroyuki Mizukami; Yasuto Hoshino; Tomofumi Misaka; Akihito Ishigami; Yasuchika Takeishi
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Ascorbic acid prevents protein oxidation in livers of senescence marker protein-30/gluconolactonase knockout mice

Geriatrics & Gerontology International
2013-10-10 | Journal article
DOI:

10.1111/ggi.12162

Contributors: Yasunori Sato; Akiko Amano; Yuki Kishimoto; Keita Takahashi; Setsuko Handa; Naoki Maruyama; Akihito Ishigami
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Akihito Ishigami via Crossref Metadata Search

Effects of Vitamin C on Cytotherapy-Mediated Muscle Regeneration

cell transplant
2013-10-04 | Journal article
DOI:

10.3727/096368912x657846

Contributors: Ah-Young Kim; Eun-Mi Lee; Eun-Joo Lee; Chang-Woo Min; Kyung-Ku Kang; Jin-Kyu Park; Il-Hwa Hong; Akihito Ishigami; Jacques P. Tremblay; Kyu-Shik Jeong
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Deimination in Alzheimer’s Disease

Protein Deimination in Human Health and Disease
2013-09 | Other
DOI:

10.1007/978-1-4614-8317-5_13

Contributors: Akihito Ishigami; Eun-Kyoung Choi; Yong-Sun Kim; Naoki Maruyama
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Deimination in Prion Diseases

Protein Deimination in Human Health and Disease
2013-09 | Other
DOI:

10.1007/978-1-4614-8317-5_12

Contributors: Eun-Kyoung Choi; Byungki Jang; Akihito Ishigami; Naoki Maruyama; Richard I. Carp; Yong-Sun Kim
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Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction

Biochemical and Biophysical Research Communications
2013-09 | Journal article
DOI:

10.1016/j.bbrc.2013.08.002

Contributors: Tomofumi Misaka; Satoshi Suzuki; Makiko Miyata; Atsushi Kobayashi; Akihito Ishigami; Tetsuro Shishido; Shu-ichi Saitoh; Isao Kubota; Yasuchika Takeishi
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Vitamin C Prevents Cigarette Smoke-Induced Pulmonary Emphysema in Mice and Provides Pulmonary Restoration

Am J Respir Cell Mol Biol
2013-09 | Journal article
DOI:

10.1165/rcmb.2013-0121oc

Contributors: Kengo Koike; Akihito Ishigami; Yasunori Sato; Toyohiro Hirai; Yiming Yuan; Etsuko Kobayashi; Kazunori Tobino; Tadashi Sato; Mitsuaki Sekiya; Kazuhisa Takahashi et al.
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Two novel sandwich ELISAs identify PAD4 levels and PAD4 autoantibodies in patients with rheumatoid arthritis

Mod Rheumatol
2013-07 | Journal article
DOI:

10.3109/s10165-012-0748-0

Contributors: Akihito Ishigami; Yoshiaki Uchida; Tsuyoshi Miyazaki; Setsuko Handa; Eun-Kyoung Choi; Yong-Sun Kim; Yasushi Kasahara; Naoki Maruyama
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Akihito Ishigami via Crossref Metadata Search

Leprdb/db Mice with Senescence Marker Protein-30 Knockout (Leprdb/dbSmp30Y/−) Exhibit Increases in Small Dense-LDL and Severe Fatty Liver Despite Being Fed a Standard Diet

PLoS ONE
2013-06-03 | Journal article
DOI:

10.1371/journal.pone.0065698

Contributors: Yoshitaka Kondo; Goji Hasegawa; Hiroshi Okada; Takafumi Senmaru; Michiaki Fukui; Naoto Nakamura; Morio Sawada; Jo Kitawaki; Takeshi Okanoue; Yuki Kishimoto et al.
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Akihito Ishigami via Crossref Metadata Search

Senescence marker protein 30 deficiency increases Parkinson's pathology by impairing astrocyte activation

Neurobiology of Aging
2013-04 | Journal article
DOI:

10.1016/j.neurobiolaging.2012.10.008

Contributors: Hyun Soo Kim; Tae Gen Son; Hee Ra Park; Yonghyun Lee; Yunjin Jung; Akihito Ishigami; Jaewon Lee
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Akihito Ishigami via Crossref Metadata Search

Senescence Marker Protein-30 (SMP30) Deficiency Impairs Myocardium-Induced Dilation of Coronary Arterioles Associated with Reactive Oxygen Species

IJMS
2013-04 | Journal article
DOI:

10.3390/ijms14059408

Contributors: Hiroyuki Mizukami; Shu-ichi Saitoh; Hirofumi Machii; Shinya Yamada; Yasuto Hoshino; Tomofumi Misaka; Akihito Ishigami; Yasuchika Takeishi
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Akihito Ishigami via Crossref Metadata Search
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