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Works (18)

Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets

Clinical and Translational Medicine
2023-04 | Journal article
DOI: 10.1002/ctm2.1232
Contributors: Susanne N. Wijesinghe; Amel Badoume; Dominika E. Nanus; Archana Sharma‐Oates; Hussein Farah; Michelangelo Certo; Fawzeyah Alnajjar; Edward T. Davis; Claudio Mauro; Mark A. Lindsay et al.
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Crossref

Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges

Pharmaceutics
2023-01 | Journal article | Author
DOI: 10.3390/pharmaceutics15010237
Contributors: Thomas Nicholson; Michael Sagmeister; Susanne N. Wijesinghe; Hussein Farah; Rowan Hardy; Simon Jones
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Multidisciplinary Digital Publishing Institute

Long Non-coding RNAs in Rheumatology

Advances in Experimental Medicine and Biology
2022 | Book chapter
DOI: 10.1007/978-3-030-92034-0_4
EID:

2-s2.0-85125553548

Part of ISSN: 22148019 00652598
Contributors: Wijesinghe, S.N.; Lindsay, M.A.; Jones, S.W.
Source: Self-asserted source
Susanne N. Wijesinghe via Scopus - Elsevier

Differential Metabotypes in Synovial Fibroblasts and Synovial Fluid in Hip Osteoarthritis Patients Support Inflammatory Responses

International Journal of Molecular Sciences
2022-03 | Journal article | Author
DOI: 10.3390/ijms23063266
Contributors: Hussein Farah; Susanne N. Wijesinghe; Thomas Nicholson; Fawzeyah Alnajjar; MICHELANGELO CERTO; Abdullah Alghamdi; Edward T. Davis; Stephen P Young; Claudio Mauro; Simon Jones
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Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1

iScience
2021 | Journal article
DOI: 10.1016/j.isci.2021.102273
EID:

2-s2.0-85102863455

Part of ISSN: 25890042
Contributors: Jones, R.; Wijesinghe, S.; Wilson, C.; Halsall, J.; Liloglou, T.; Kanhere, A.
Source: Self-asserted source
Susanne N. Wijesinghe via Scopus - Elsevier

Involvements of long noncoding RNAs in obesity-associated inflammatory diseases

Obesity Reviews
2021 | Journal article
DOI: 10.1111/OBR.13156
WOSUID: WOS:000582152400001
Contributors: Wijesinghe, Susanne N.; Nicholson, Thomas; Tsintzas, Kostas; Jones, Simon W.
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Web of Science Researcher Profile Sync
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Preferred source (of 2)‎

Novel gene variants in patients with platelet-based bleeding using combined exome sequencing and RNAseq murine expression data

Journal of Thrombosis and Haemostasis
2021 | Journal article
DOI: 10.1111/JTH.15119
WOSUID: WOS:000585891000001
Contributors: Khan, Abdullah O.; Stapley, Rachel J.; Pike, Jeremy A.; Wijesinghe, Susanne N.; Reyat, Jasmeet S.; Almazni, Ibrahim; Machlus, Kellie R.; Morgan, Neil, V
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Web of Science Researcher Profile Sync
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Preferred source (of 2)‎

Synovial tissue from sites of joint pain in knee osteoarthritis patients exhibits a differential phenotype with distinct fibroblast subsets

EBioMedicine
2021 | Journal article
DOI: 10.1016/j.ebiom.2021.103618
EID:

2-s2.0-85116644986

Part of ISSN: 23523964
Contributors: Nanus, D.E.; Badoume, A.; Wijesinghe, S.N.; Halsey, A.M.; Hurley, P.; Ahmed, Z.; Botchu, R.; Davis, E.T.; Lindsay, M.A.; Jones, S.W.
Source: Self-asserted source
Susanne N. Wijesinghe via Scopus - Elsevier

The expression and function of metastases associated lung adenocarcinoma transcript-1 long non-coding rna in subchondral bone and osteoblasts from patients with osteoarthritis

Cells
2021 | Journal article
DOI: 10.3390/cells10040786
EID:

2-s2.0-85105236763

Part of ISSN: 20734409
Contributors: Alnajjar, F.A.; Sharma-Oates, A.; Wijesinghe, S.N.; Farah, H.; Nanus, D.E.; Nicholson, T.; Davis, E.T.; Jones, S.W.
Source: Self-asserted source
Susanne N. Wijesinghe via Scopus - Elsevier

Oligonucleotide Therapies in the Treatment of Arthritis: A Narrative Review

Biomedicines
2021-07 | Journal article | Author
DOI: 10.3390/biomedicines9080902
Contributors: Susanne N. Wijesinghe; Mark A. Lindsay; Simon Jones
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Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Oligonucleotide Therapies in the Treatment of Inflammatory Joint Disease

2021-06-28 | Preprint
DOI: 10.20944/preprints202106.0683.v1
Contributors: Susanne N Wijesinghe; Mark A Lindsay; Simon W Jones
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Crossref

A long intergenic non-coding RNA regulates nuclear localisation of DNA methyl transferase-1

bioRxiv
2020 | Other
DOI: 10.1101/2020.03.11.985705
EID:

2-s2.0-85102608827

Part of ISSN: 26928205
Contributors: Jones, R.; Wijesinghe, S.; Halsall, J.; Kanhere, A.
Source: Self-asserted source
Susanne N. Wijesinghe via Scopus - Elsevier

IDENTIFICATION OF SYNOVIAL FIBROBLASTS SUBSETS ASSOCIATED WITH PAIN AND PROGRESSION OF KNEE OSTEOARTHRITIS BY SINGLE CELL SEQUENCING

Osteoarthritis and Cartilage
2020 | Journal article
DOI: 10.1016/J.JOCA.2020.02.220
WOSUID: WOS:000527813600206
Contributors: Nanus, D. E.; Badoume, A.; Wijesinghe, S. N.; Hurley, P.; Davis, E. T.; Lindsay, M. A.; Jones, S. W.
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Web of Science Researcher Profile Sync

OBESE SYNOVIAL FIBROBLASTS EXHIBIT SINGLE CELL SUBSETS WITH SPECIFIC PATHOLOGICAL INFLAMMATORY FUNCTIONS IN OSTEOARTHRITIS PATIENTS

Osteoarthritis and Cartilage
2020 | Journal article
DOI: 10.1016/J.JOCA.2020.02.128
WOSUID: WOS:000527813600117
Contributors: Wijesinghe, S. N.; Badoume, A.; Nanus, D. E.; Davis, E. T.; Lindsay, M. A.; Jones, S. W.
Source: check_circle
Web of Science Researcher Profile Sync

Regulation of the Inflammatory Synovial Fibroblast Phenotype by Metastasis-Associated Lung Adenocarcinoma Transcript 1 Long Noncoding RNA in Obese Patients With Osteoarthritis.

Arthritis & rheumatology
2019-11-04 | Journal article
DOI: 10.1002/art.41158
PMID: 31682073
Source: Self-asserted source
Susanne N. Wijesinghe
grade
Preferred source (of 3)‎

The combination of local infiltration analgesia reagents increases their detrimental effect on human hip OA patient osteoblast viability and function.

Journal of orthopaedics
2019-06-10 | Journal article
DOI: 10.1016/j.jor.2019.06.014
PMID: 31516213
Source: Self-asserted source
Susanne N. Wijesinghe
grade
Preferred source (of 3)‎

A novel form of JARID2 is required for differentiation in lineage-committed cells.

The EMBO journal
2018-12-20 | Journal article
DOI: 10.15252/embj.201798449
PMID: 30573669
PMC: PMC6356158
Source: Self-asserted source
Susanne N. Wijesinghe
grade
Preferred source (of 3)‎

Oligonucleotide Therapeutics for Age-Related Musculoskeletal Disorders: Successes and Challenges
Source: check_circle
Multidisciplinary Digital Publishing Institute

Peer review (7 reviews for 5 publications/grants)

Review activity for Biological Research. (1)
Review activity for Biotechnology and applied biochemistry. (1)
Review activity for Molecular and cellular biochemistry. (1)
Review activity for Molecular biology reports. (1)
Review activity for Rheumatology (3)
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