Personal information

No personal information available

Activities

Collapse all

Works (50 of 111)

Items per page:
Page 1 of 3

Adaptive Proteomic Changes in Protein Metabolism and Mitochondrial Alterations Associated with Resistance to Trastuzumab and Pertuzumab Therapy in HER2-Positive Breast Cancer

International Journal of Molecular Sciences
2025-02-12 | Journal article
DOI: 10.3390/ijms26041559
Contributors: Juan Madoz-Gúrpide; Juana Serrano-López; Marta Sanz-Álvarez; Miriam Morales-Gallego; Socorro María Rodríguez-Pinilla; Ana Rovira; Joan Albanell; Federico Rojo
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Generation and Characterization of Trastuzumab/Pertuzumab-Resistant HER2-Positive Breast Cancer Cell Lines

International Journal of Molecular Sciences
2023-12-22 | Journal article
DOI: 10.3390/ijms25010207
Contributors: Marta Sanz-Álvarez; Melani Luque; Miriam Morales-Gallego; Ion Cristóbal; Natalia Ramírez-Merino; Yamileth Rangel; Yann Izarzugaza; Pilar Eroles; Joan Albanell; Juan Madoz-Gúrpide et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Deregulation of the miR-19b/PPP2R5E Signaling Axis Shows High Functional Impact in Colorectal Cancer Cells

International Journal of Molecular Sciences
2023-04-24 | Journal article
DOI: 10.3390/ijms24097779
Contributors: Andrea Santos; Ion Cristóbal; Cristina Caramés; Melani Luque; Marta Sanz-Álvarez; Juan Madoz-Gúrpide; Federico Rojo; Jesús García-Foncillas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

miR-146a-5p Promotes Angiogenesis and Confers Trastuzumab Resistance in HER2+ Breast Cancer

Cancers
2023-04-04 | Journal article
DOI: 10.3390/cancers15072138
Contributors: Paula Cabello; Sandra Torres-Ruiz; Anna Adam-Artigues; Jaume Forés-Martos; María Teresa Martínez; Cristina Hernando; Sandra Zazo; Juan Madoz-Gúrpide; Ana Rovira; Octavio Burgués et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

High VEGFR3 Expression Reduces Doxorubicin Efficacy in Triple-Negative Breast Cancer

International Journal of Molecular Sciences
2023-02-10 | Journal article
DOI: 10.3390/ijms24043601
Contributors: Sandra Torres-Ruiz; Eduardo Tormo; Iris Garrido-Cano; Ana Lameirinhas; Federico Rojo; Juan Madoz-Gúrpide; Octavio Burgués; Cristina Hernando; Begoña Bermejo; María Teresa Martínez et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Tumor-Infiltrating Lymphocytes and Immune Response in HER2-Positive Breast Cancer

Cancers
2022-12-08 | Journal article
DOI: 10.3390/cancers14246034
Contributors: Melani Luque; Marta Sanz-Álvarez; Miriam Morales-Gallego; Juan Madoz-Gúrpide; Sandra Zazo; Carolina Domínguez; Alicia Cazorla; Yann Izarzugaza; Juan Luis Arranz; Ion Cristóbal et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

MicroRNA-19b Plays a Key Role in 5-Fluorouracil Resistance and Predicts Tumor Progression in Locally Advanced Rectal Cancer Patients

International Journal of Molecular Sciences
2022-10-18 | Journal article
DOI: 10.3390/ijms232012447
Contributors: Andrea Santos; Ion Cristóbal; Jaime Rubio; Cristina Caramés; Melani Luque; Marta Sanz-Álvarez; Sandra Zazo; Juan Madoz-Gúrpide; Federico Rojo; Jesus García-Foncillas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

miR‐99a‐5p modulates doxorubicin resistance via the COX‐2/ABCG2 axis in triple‐negative breast cancer: from the discovery to in vivo studies

Cancer Communications
2022-08-23 | Journal article
DOI: 10.1002/cac2.12352
Part of ISSN: 2523-3548
Part of ISSN: 2523-3548
Contributors: JUAN MADOZ-GURPIDE
Source: Self-asserted source
JUAN MADOZ-GURPIDE

CIP2A as a Key Regulator for AKT Phosphorylation Has Partial Impact Determining Clinical Outcome in Breast Cancer

Journal of Clinical Medicine
2022-03-14 | Journal article
DOI: 10.3390/jcm11061610
Contributors: Melani Luque; Ion Cristóbal; Marta Sanz-Álvarez; Andrea Santos; Sandra Zazo; Pilar Eroles; Oriol Arpí; Ana Rovira; Joan Albanell; Juan Madoz-Gúrpide et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

MicroRNA-199b Deregulation Shows Oncogenic Properties and Promising Clinical Value as Circulating Marker in Locally Advanced Rectal Cancer Patients

International Journal of Molecular Sciences
2022-02-17 | Journal article
DOI: 10.3390/ijms23042203
Contributors: Andrea Santos; Ion Cristóbal; Jaime Rubio; Cristina Caramés; Melani Luque; Marta Sanz-Alvarez; Miriam Morales-Gallego; Juan Madoz-Gúrpide; Federico Rojo; Jesús García-Foncillas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Expression of Phosphorylated BRD4 Is Markedly Associated with the Activation Status of the PP2A Pathway and Shows a Strong Prognostic Value in Triple Negative Breast Cancer Patients

Cancers
2021 | Journal article
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Low MicroRNA‐19b Expression Shows a Promising Clinical Impact in Locally Advanced Rectal Cancer

Cancers
2021 | Journal article
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Targeted Therapy Modulates the Secretome of Cancer-Associated Fibroblasts to Induce Resistance in HER2-Positive Breast Cancer

International Journal of Molecular Sciences
2021-12 | Journal article | Author
DOI: 10.3390/ijms222413297
Contributors: Melani Luque; Marta Sanz-Álvarez; Andrea Santamaría; Sandra Zazo; Ion Cristobal; Lorena de la Fuente; Pablo Minguez; Pilar Eroles; Ana Rovira; Joan Albanell et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Validation of microRNA-199b as A Promising Predictor of Outcome and Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer Patients

Cancers
2021-10-05 | Journal article
DOI: 10.3390/cancers13195003
Contributors: Ion Cristóbal; Andrea Santos; Jaime Rubio; Cristina Caramés; Sandra Zazo; Marta Sanz-Álvarez; Melani Luque; Juan Madoz-Gúrpide; Federico Rojo; Jesús García-Foncillas
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

The Novel Oral mTORC1/2 Inhibitor TAK-228 Reverses Trastuzumab Resistance in HER2-Positive Breast Cancer Models

Cancers
2021-06-03 | Journal article
DOI: 10.3390/cancers13112778
Contributors: Marta Sanz-Álvarez; Ester Martín-Aparicio; Melani Luque; Sandra Zazo; Javier Martínez-Useros; Pilar Eroles; Ana Rovira; Joan Albanell; Juan Madoz-Gúrpide; Federico Rojo
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

MicroRNA-199b deregulation shows a strong SET-independent prognostic value in early-stage colorectal cancer

Journal of Clinical Medicine
2020 | Journal article
Source: Self-asserted source
JUAN MADOZ-GURPIDE

MicroRNA-199b Downregulation Confers Resistance to 5-Fluorouracil Treatment and Predicts Poor Outcome and Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Patients

Cancers
2020 | Journal article
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Autocrine CCL5 Effect Mediates Trastuzumab Resistance by ERK Pathway Activation in HER2-Positive Breast Cancer

Mol Cancer Ther
2020-08 | Journal article
DOI: 10.1158/1535-7163.MCT-19-1172
Part of ISSN: 1538-8514 (Electronic) 1535-7163 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

The Molecular Mechanisms Involved in the miR-29a-5p/STAT3 Signaling Loop in Ulcerative Colitis-Associated Colorectal Cancer Still Remain Unclear

Inflamm Bowel Dis
2020-07 | Journal article
DOI: 10.1093/ibd/izaa130
Part of ISSN: 1536-4844 (Electronic) 1078-0998 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Functional and Clinical Impact of CircRNAs in Oral Cancer

Cancers
2020-04 | Journal article
DOI: 10.3390/cancers12041041
Part of ISSN: 2072-6694 (Print) 2072-6694 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

The Hippo Pathway Transducers YAP1/TEAD Induce Acquired Resistance to Trastuzumab in HER2-Positive Breast Cancer

Cancers
2020-04 | Journal article
DOI: 10.3390/cancers12051108
Part of ISSN: 2072-6694 (Print) 2072-6694 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Deregulation of SET is associated with tumor progression and predicts adverse outcome in patients with early-stage colorectal cancer

Top 5 Contributions in Medical Research
2019 | Book chapter
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Deregulation of SET is Associated with Tumor Progression and Predicts Adverse Outcome in Patients with Early-Stage Colorectal Cancer

Journal of Clinical Medicine
2019 | Journal article
Part of ISSN: 2077-0383
Source: Self-asserted source
JUAN MADOZ-GURPIDE

The miRNA-449 family mediates doxorubicin resistance in triple-negative breast cancer by regulating cell cycle factors

Sci Rep
2019-03 | Journal article
DOI: 10.1038/s41598-019-41472-y
Part of ISSN: 2045-2322 (Electronic) 2045-2322 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

SET overexpression promotes colorectal cancer progression and determines poor outcome in patients with localized disease

ANNALS OF ONCOLOGY
2018 | Journal article
Part of ISSN: 0923-7534
Part of ISSN: 1569-8041
Contributors: Torrejon, B.; Pedregal Trujillo, M.; Santos, A.; Rubio, J.; Luque, M.; Sanz, M.; Carames, C.; Zazo, S.; Madoz-Gurpide, J.; Rojo, F. et al.
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Recent Insights into the Development of Preclinical Trastuzumab- Resistant HER2+ Breast Cancer Models

Current Medicinal Chemistry
2018-12 | Journal article
DOI: 10.2174/0929867323666161216144659
Part of ISSN: 1875-533X (Electronic) 0929-8673 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Analysis of Potential Alterations Affecting SETBP1 as a Novel Contributing Mechanism to Inhibit PP2A in Colorectal Cancer Patients

World J Surg
2018-11 | Journal article
DOI: 10.1007/s00268-018-4684-9
Part of ISSN: 1432-2323 (Electronic) 0364-2313 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

PP2A regulates signaling through hormonal receptors in breast cancer with important therapeutic implications

Biochim Biophys Acta
2017-09 | Journal article
DOI: 10.1016/j.bbcan.2017.08.005
Part of ISSN: 0006-3002 (Print) 0006-3002 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Defective cyclin B1 induction in trastuzumab-emtansine (T-DM1) acquired resistance in HER2-positive breast cancer

Clin Cancer Res
2017-08 | Journal article
DOI: 10.1158/1078-0432.CCR-17-0696
Part of ISSN: 1078-0432 (Print) 1078-0432 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Downregulation of microRNA-199b predicts unfavorable prognosis and emerges as a novel therapeutic target which contributes to PP2A inhibition in metastatic colorectal cancer

Oncotarget
2017-06 | Journal article
DOI: 10.18632/oncotarget.11174
Part of ISSN: 1949-2553 (Electronic) 1949-2553 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Letter to the Editor: Is miR-199b-3p really involved in the migration ability of bone marrow mesenchymal stem cells?

J Leukoc Biol
2017-05 | Journal article
DOI: 10.1189/jlb.2LT0117-034
Part of ISSN: 1938-3673 (Electronic) 0741-5400 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

PP2A plays a key role in inflammation and cancer through tristetraprolin activation

Ann Rheum Dis
2017-05 | Journal article
DOI: 10.1136/annrheumdis-2016-210684
Part of ISSN: 1468-2060 (Electronic) 0003-4967 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

CIP2A confirms its prognostic value in triple-negative breast cancer

Oncogene
2017-01 | Journal article
DOI: 10.1038/onc.2016.474
Part of ISSN: 1476-5594 (Electronic) 0950-9232 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Comment on 'MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells'

Br J Cancer
2017-01 | Journal article
DOI: 10.1038/bjc.2016.409
Part of ISSN: 1532-1827 (Electronic) 0007-0920 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Generation, characterization, and maintenance of trastuzumab-resistant HER2+ breast cancer cell lines

Am J Cancer Res
2016 | Journal article
Part of ISSN: 2156-6976 (Print) 2156-6976 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Proteomic Profiling of Ewing Sarcoma Reveals a Role for TRAF6 in Proliferation and Ribonucleoproteins/RNA Processing

Journal of Proteomics & Bioinformatics
2016 | Journal article
DOI: 10.4172/jpb.1000403
Part of ISSN: 0974-276X
Contributors: Juan Madoz Gurpide; David Herrero Martin
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Proteomic Profiling of Ewing Sarcoma Reveals a Role for TRAF6 in Proliferation and Ribonucleoproteins/RNA Processing

J Proteomics Bioinform
2016 | Journal article
DOI: 10.4172/jpb.1000403J
Part of ISSN: 0974-276X JPB
Source: Self-asserted source
JUAN MADOZ-GURPIDE

c-Jun N-Terminal Kinase Inactivation by Mitogen-Activated Protein Kinase Phosphatase 1 Determines Resistance to Taxanes and Anthracyclines in Breast Cancer

Mol Cancer Ther
2016-11 | Journal article
DOI: 10.1158/1535-7163.MCT-15-0920
Part of ISSN: 1538-8514 (Electronic) 1535-7163 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Potential therapeutic value of miR-425-5p in metastatic colorectal cancer

Journal of Cellular and Molecular Medicine
2016-11 | Journal article
DOI: 10.1111/jcmm.12902
Part of ISSN: 1582-4934 (Electronic) 1582-1838 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Deregulation of miR-92a in locally advanced rectal cancer

Genes Chromosomes Cancer
2016-07 | Journal article
DOI: 10.1002/gcc.22357
Part of ISSN: 1098-2264 (Electronic) 1045-2257 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Non-canonical NF-kappaB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma

Br J Cancer
2016-07 | Journal article
DOI: 10.1038/bjc.2016.204
Part of ISSN: 1532-1827 (Electronic) 0007-0920 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Comment on Goldsworthy et al. Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes. Diabetes 2016;65:1434-1446

Diabetes
2016-06 | Journal article
DOI: 10.2337/db16-0249
Part of ISSN: 1939-327X (Electronic) 0012-1797 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Cross Talk between Wnt/beta-Catenin and CIP2A/Plk1 Signaling in Prostate Cancer: Promising Therapeutic Implications

Mol Cell Biol
2016-06 | Journal article
DOI: 10.1128/MCB.00130-16
Part of ISSN: 1098-5549 (Electronic) 0270-7306 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Potential anti-tumor effects of FTY720 associated with PP2A activation: a brief review

Curr Med Res Opin
2016-06 | Journal article
DOI: 10.1185/03007995.2016.1162774
Part of ISSN: 1473-4877 (Electronic) 0300-7995 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Clinical Usefulness of 5-FU Metabolic Enzymes as Predictive Markers of Response to Chemotherapy in Colorectal Cancer

World J Surg
2016-04 | Journal article
DOI: 10.1007/s00268-015-3176-4
Part of ISSN: 1432-2323 (Electronic) 0364-2313 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Determination of True ERBB2 Gene Amplification in Breast Cancer by Quantitative PCR Using a Reference and a Novel Control Gene

APPL IMMUNOHISTOCHEM MOL MORPHOL
2016-03 | Journal article
DOI: 10.1097/PAI.0000000000000160
Part of ISSN: 1533-4058 (Electronic) 1533-4058 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Activation of MET pathway predicts poor outcome to cetuximab in patients with recurrent or metastatic head and neck cancer

J Transl Med
2015 | Journal article
DOI: 10.1186/s12967-015-0633-7
Part of ISSN: 1479-5876 (Electronic) 1479-5876 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Activation of the Tumor Suppressor PP2A Emerges as a Potential Therapeutic Strategy for Treating Prostate Cancer

Marine Drugs
2015 | Journal article
Part of ISSN: 1660-3397
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma

Int J Mol Sci
2015 | Journal article
DOI: 10.3390/ijms160819447
Part of ISSN: 1422-0067 (Electronic) 1422-0067 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE

Thymidylate synthase expression as a predictive biomarker of pemetrexed sensitivity in advanced non-small cell lung cancer

BMC Pulm Med
2015 | Journal article
DOI: 10.1186/s12890-015-0132-x
Part of ISSN: 1471-2466 (Electronic) 1471-2466 (Linking)
Source: Self-asserted source
JUAN MADOZ-GURPIDE
Items per page:
Page 1 of 3
How many people are using ORCID?