Gerald Mboowa (0000-0001-8445-9414)

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Biography

Gerald Mboowa is a scientist committed to advancing the integration and application of genome sequencing technologies to address critical challenges in health and disease. His work spans outbreak investigation, pathogen characterization, and antimicrobial resistance (AMR) surveillance, employing cutting-edge sequencing and bioinformatics tools. In AMR research, Gerald focuses on uncovering the genomic determinants of resistance and virulence, elucidating the mechanisms underlying these traits to inform better diagnostics, treatments, and policies.

By leveraging data science, genomics, and bioinformatics, his research contributes to improving our understanding of complex biological systems and translating genomic insights into actionable strategies for enhancing global health outcomes.

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Broad Institute: Cambridge, US

2024-10-01 to present | Senior Data Engineer (Global Pathogen Genomics)

Employment

Gerald Mboowa

https://orcid.org/0000-0001-8445-9414

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Biography

Activities

Employment (5)

Broad Institute: Cambridge, US

Africa Centres for Disease Control and Prevention: Addis Ababa, ET

The African Center of Excellence in Bioinformatics & Data-Intensive Sciences, Infectious Diseases Institute, McKinnell Knowledge Centre, Makerere University: Kampala, Uganda, UG

Infectious Diseases Institute: Kampala, Central Region, UG

Makerere University College of Health Sciences: Kampala, UG

Education and qualifications (3)

Makerere University : Kampala, UG

University of Cambridge: Cambridge, Cambridgeshire, GB

Baylor College of Medicine: Houston, Texas, US

Professional activities (5)

BMC Genomics: London, GB

Journal of Global Health, Epidemiology and Genomics: Cambridge, GB

Public Health Alliance for Genomic Epidemiology (PHA4GE): Cape Town, ZA

BMC Infectious Diseases: London, GB

African Association for research and control of Anti-Microbial Resistance "AAAMR": Bamako, ML

Funding (5)

Trends in the antimicrobial resistance profiles in the surgical wards at Mulago National Referral Hospital, Uganda

Assessing knowledge, attitudes, perceptions, and skills towards the use of face masks: A community- level perspective in Uganda

Understanding transmission dynamics and acquisition of Antimicrobial Resistance at referral hospitals and community settings in East Africa

Training Health Researchers into Vocational Excellence in East Africa

Collaborative African Genomics Network (CAfGEN)

Works (50 of 132)

Molecular epidemiology of recurrent zoonotic transmission of mpox virus in West Africa

Table 3. The different pathogens that have been sequenced and publicly shared via SRA:NCBI from different countries in Africa (at least 12 Terabytes of sequence data).xlsx

Extracellular Hydrolytic Enzyme Activities and Biofilm Formation in Candida species Isolated from People Living with Human Immunodeficiency Virus with Oropharyngeal Candidiasis at HIV/AIDS Clinics in Uganda

Whole genome-based characterization of extended-spectrum β-lactamase-producing Enterobacter cloacae from orthopedic patients and environment of a tertiary referral hospital in Tanzania

Unlocking the future of complex human diseases prediction: multi-omics risk score breakthrough

High KIR diversity in Uganda and Botswana children living with HIV

Machine learning-based prediction of antibiotic resistance in Mycobacterium tuberculosis clinical isolates from Uganda.

Reported prevalence and comparison of diagnostic approaches for Candida africana: a systematic review with meta-analysis.

Multicountry genomic analysis underscores regional cholera spread in Africa

Inclusiveness of the All of Us Research Program improves polygenic risk scores and fosters genomic medicine for all

Lack of Candida africana in Ugandan pregnant women: results from a pilot study using MALDI-ToF.

Serological Status of Vaccine and Hepatitis B Virus Exposure Among Children Under 5 and Aged 15–17 Years in Kampala, Uganda

Africa in the era of pathogen genomics: Unlocking data barriers.

The rise of pathogen genomics in Africa

Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda

HIV-DRIVES: HIV drug resistance identification, variant evaluation, and surveillance pipeline.

The pandemic agreement: an African perspective.

Metagenomics insights into the microbial resistome and virulome composition of Kampala’s wastewater

CDC Trioplex diagnostic assay underperforms in detection of circulating Chikungunya West African genotype

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline

Molecular epidemiology of recurrent zoonotic transmission of mpox virus in West Africa

Genomic epidemiology uncovers the timing and origin of the emergence of mpox in humans

Prevalence of Oropharyngeal Candidiasis and distribution of Candida species among People Living with Human Immunodeficiency Virus in Africa: a systematic review and meta-analysis

In Vitro Evaluation of the Virulence Attributes of Oropharyngeal Candida Species Isolated from People Living with Human Immunodeficiency Virus with Oropharyngeal Candidiasis on Antiretroviral Therapy

The rise of pathogen genomics in Africa

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline

The dawn of a cure for sickle cell disease through CRISPR‐based treatment: A critical test of equity in public health genomics

Generalizability of machine learning in predicting antimicrobial resistance in E. coli: a multi-country case study in Africa.

Climate-influenced vector-borne diseases in Africa: a call to empower the next generation of African researchers for sustainable solutions.

Distribution and antifungal susceptibility profile of oropharyngeal <i>Candida</i> species isolated from people living with HIV in the era of universal test and treat policy in Uganda.

A Digital One Health framework to integrate data for public health decision-making

A systematic review reveals that African children of 15-17 years demonstrate low hepatitis B vaccine seroprotection rates.

First outbreak of Dengue virus fever in Chad, 2023

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline

Reviewing the journey to the clinical application of bacteriophages to treat multi-drug-resistant bacteria.

Reviewing the journey to the clinical application of bacteriophages to treat multi- drug-resistant bacteria

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance Pipeline

Virulence genes and plasmid replicon profiles of selected β-Lactamases producing Acinetobacter baumannii from orthopedic patients and environment in a tertiary referral hospital in Tanzania, East Africa.

Unraveling virulence determinants in extended-spectrum beta-lactamase-producing Escherichia coli from East Africa using whole-genome sequencing

Impact of high human genetic diversity in Africa on immunogenicity and efficacy of RTS,S/AS01 vaccine

Genomic analysis of selected Vibrio cholerae isolates from the 2023 Cholera outbreak in Zambia: A use-case for integration of whole-genome sequencing in cholera outbreak response

Unlocking the Potential of Genomic Data to Inform Typhoid Fever Control Policy: Supportive Resources for Genomic Data Generation, Analysis, and Visualization

A pan-African pathogen genomics data sharing platform to support disease outbreaks

Reduced CCR5 expression among Uganda HIV controllers

Metatranscriptomic analysis of the gut microbiome of black soldier fly larvae reared on lignocellulose-rich fiber diets unveils key lignocellulolytic enzymes.

No association of a Vascular endothelial growth factor A (VEGFA) gene polymorphism with pre-eclampsia among pregnant women in Uganda.

Antimicrobial susceptibility surveillance and antimicrobial resistance in Neisseria gonorrhoeae in Africa from 2001 to 2020: A mini-review

No association of a Vascular endothelial growth factor A (VEGFA) gene polymorphism with pre-eclampsia among pregnant women in Uganda.

Molecular Epidemiology and Diversity of SARS-CoV-2 in Ethiopia, 2020-2022.