Personal information

United States

Activities

Employment (1)

University of Pennsylvania: Philadelphia, PA, US

PI
Employment
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University of Pennsylvania via ORCID Member Portal

Education and qualifications (2)

Case Western Reserve University: Cleveland, OH, US

1992 to 1999 | M.D.,Ph.D.
Education
Source: Self-asserted source
Todd Ridky

University of North Carolina at Chapel Hill: NC, NC, US

1988 to 1992 | B.S. (Chemistry)
Education
Source: Self-asserted source
Todd Ridky

Works (50 of 56)

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Page 1 of 2

LNS8801: An enantiomerically pure agonist of the G protein-coupled estrogen receptor suitable for clinical development

2024-12-01 | Preprint
Contributors: Christopher A. Natale; Sophia Mercado; Richard Zhuang; Cristina Aguirre-Portolés; Israel Olayide; Christopher K. Arnatt; John T. Seykora; Tina K. Garyantes; Wayne Luke; Todd W. Ridky
Source: check_circle
Crossref

Data from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Data from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 1 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 1 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 2 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 2 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 3 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 3 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 4 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 4 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 5 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 5 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 6 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 6 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 7 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 7 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 8 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Supplementary Figure 8 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S1 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S1 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S2 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S2 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S3 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S3 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S4 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Table S4 from ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

2023-03-31 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression

Nature Communications
2022-12-23 | Journal article
Contributors: Jaskaren Kohli; Chen Ge; Eleni Fitsiou; Miriam Doepner; Simone M. Brandenburg; William J. Faller; Todd W. Ridky; Marco Demaria
Source: check_circle
Crossref

ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma

Cancer Research
2021-12-01 | Journal article
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Drug Resistant Melanoma May Be Vulnerable to Inhibitors of Serine Synthesis

Journal of Investigative Dermatology
2020-11 | Journal article
Contributors: Miriam Doepner; In Young Lee; Todd W. Ridky
Source: check_circle
Crossref

Pharmacologic Activation of the G Protein–Coupled Estrogen Receptor Inhibits Pancreatic Ductal Adenocarcinoma

Cellular and Molecular Gastroenterology and Hepatology
2020-05 | Journal article
Contributors: Christopher A. Natale; Jinyang Li; Jason R. Pitarresi; Robert J. Norgard; Tzvete Dentchev; Brian C. Capell; John T. Seykora; Ben Z. Stanger; Todd W. Ridky
Source: check_circle
Crossref

ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

2020-03-13 | Preprint
Contributors: Cristina Aguirre-Portolés; Riley Payne; Aspen Trautz; J. Kevin Foskett; Christopher A. Natale; John T. Seykora; Todd W. Ridky
Source: check_circle
Crossref

Exophilin-5 Supports Lysosome-Mediated Trafficking Required for Epidermal Differentiation

Journal of Investigative Dermatology
2019-10 | Journal article
Contributors: Christine L. Monteleon; In Young Lee; Todd W. Ridky
Source: check_circle
Crossref

Pharmacologic activation of the G protein-coupled estrogen receptor inhibits pancreatic ductal adenocarcinoma

2018-07-09 | Other
Contributors: Christopher A. Natale; Jinyang Li; Tzvete Dentchev; Brian C. Capell; John T. Seykora; Ben Z. Stanger; Todd W. Ridky
Source: check_circle
Crossref

Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade

eLife
2018-01-16 | Journal article
Contributors: Christopher A Natale; Jinyang Li; Junqian Zhang; Ankit Dahal; Tzvete Dentchev; Ben Z Stanger; Todd W Ridky
Source: check_circle
Crossref

Non-classical estrogen signaling inhibits melanoma and improves response to PD-1 blockade

2017-06-06 | Preprint
Contributors: Christopher A. Natale; Jinyang Li; Junqian Zhang; Ankit Dahal; Ben Z. Stanger; Todd W. Ridky
Source: check_circle
Crossref

Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors

eLife
2016-04-26 | Journal article
Contributors: Christopher A Natale; Elizabeth K Duperret; Junqian Zhang; Rochelle Sadeghi; Ankit Dahal; Kevin Tyler O'Brien; Rosa Cookson; Jeffrey D Winkler; Todd W Ridky
Source: check_circle
Crossref

CDKN2B loss promotes progression from benign melanocytic nevus to melanoma

Cancer Discovery
2015-07 | Journal article
Contributors: A. S. McNeal; K. Liu; V. Nakhate; C. A. Natale; E. K. Duperret; B. C. Capell; T. Dentchev; S. L. Berger; M. Herlyn; J. T. Seykora et al.
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

IQGAP1 and IQGAP3 Serve Individually Essential Roles in Normal Epidermal Homeostasis and Tumor Progression

J Investig Dermatol
2015-04-07 | Journal article
DOI:

10.1038/jid.2015.140

Contributors: Christine L Monteleon; Andrew McNeal; Elizabeth K Duperret; Seung J Oh; Emily Schapira; Todd W Ridky
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Vismodegib Resistance in Basal Cell Carcinoma: Not a Smooth Fit

Cancer Cell
2015-03 | Journal article
DOI:

10.1016/j.ccell.2015.02.009

Contributors: Todd W. Ridky; George Cotsarelis
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Kindler syndrome in mice and men

Cancer Biology & Therapy
2014-06-11 | Journal article
DOI:

10.4161/cbt.29482

Contributors: Elizabeth K Duperret; Todd W Ridky
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Activating FGFR3 mutations cause mild hyperplasia in human skin, but are insufficient to drive benign or malignant skin tumors

Cell Cycle
2014-03 | Journal article
DOI:

10.4161/cc.28492

Contributors: Elizabeth K Duperret; Seung Ja Oh; Andrew McNeal; Stephen M Prouty; Todd W Ridky
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Rous Sarcoma Virus Retropepsin and Avian Myeloblastosis Virus Retropepsin

Handbook of Proteolytic Enzymes
2013 | Other
DOI:

10.1016/b978-0-12-382219-2.00048-x

Contributors: Todd W. Ridky; Jonathan Leis
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Focal adhesion complex proteins in epidermis and squamous cell carcinoma

Cell Cycle
2013-10 | Journal article
DOI:

10.4161/cc.26385

Contributors: Elizabeth Duperret; Todd W Ridky
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma

J. Clin. Invest.
2012-02-01 | Journal article
DOI:

10.1172/jci57415

Contributors: Vladimir Ratushny; Michael D. Gober; Ryan Hick; Todd W. Ridky; John T. Seykora
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia

Nat Med
2010-11 | Journal article
DOI:

10.1038/nm.2265

Contributors: Todd W Ridky; Jennifer M Chow; David J Wong; Paul A Khavari
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Skin Nodules in a Patient With Acute Myeloid Leukemia and Neurological Deterioration—Quiz Case

Arch Dermatol
2010-09-01 | Journal article
DOI:

10.1001/archdermatol.2010.216-a

Contributors: Kerri E. Rieger; Todd W. Ridky; Uma N. Sundram
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

The Hair Follicle Bulge Stem Cell Niche Resists Transformation by the Hedgehog Pathway

Cell Stem Cell
2010-04 | Journal article
DOI:

10.1016/j.stem.2010.03.009

Contributors: Todd W. Ridky; Paul A. Khavari
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Module Map of Stem Cell Genes Guides Creation of Epithelial Cancer Stem Cells

Cell Stem Cell
2008-04 | Journal article
DOI:

10.1016/j.stem.2008.02.009

Contributors: David J. Wong; Helen Liu; Todd W. Ridky; David Cassarino; Eran Segal; Howard Y. Chang
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search

Nonmelanoma skin cancer

Journal of the American Academy of Dermatology
2007-09 | Journal article
DOI:

10.1016/j.jaad.2007.01.033

Contributors: Todd W. Ridky
Source: Self-asserted source
Todd Ridky via Crossref Metadata Search
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Page 1 of 2

Peer review (2 reviews for 2 publications/grants)

Review activity for Nature communications (1)
Review activity for Oncogene. (1)